This 2011 update of Guidelines for the programmatic management of drug-resistant tuberculosis is intended as a tool for use by public health professionals working in response
to the Sixty-second World Health Assembly’s resolution on prevention and control of multidrug-resistant tuberculosis and e...xtensively drug-resistant tuberculosis.
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WHO/CDS/CSR/EDC/99.2 Plague Manual
Epidemiology, Distribution, Surveillance and Control
À l’heure où des techniques innovantes de dépistage sur le lieu de soins (POC) sont mises sur le marché, le présent rapport soumet à l’attention des gouvernements un examen des principaux aspects relatifs à leur introduction et à leur extension au sein des programmes publics nationaux. L...’élargissement de la portée de cette stratégie aux réseaux nationaux de dépistage des laboratoires conventionnels contribuerait à la réalisation des objectifs d’accélération de la riposte visant à mettre fin à l’épidémie de sida d’ici à 2030.
Le dépistage sur le lieu de soins, lorsqu’il est stratégiquement mis en place et intégré dans les réseaux nationaux de dépistage, peut contribuer à promouvoir des changements et à améliorer la prestation des services cliniques et de dépistage. Le présent document s’inspire de l’expérience acquise en matière d’introduction, par le biais de financements catalysateurs, de techniques de dépistage sur le lieu de soin dans les programmes et les marchés de nombreux pays d’Afrique subsaharienne pour défendre ce point de vue.
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Part of the CBM Prevention Toolkit on “Recognising Impairments at Birth”
Investigación original / Original research
Rev Panam Salud Publica 35(1), 2014
Antimicrobial Resistance (AMR) occurs when organisms that cause disease are no longer susceptible/responsive to antimicrobial agents that previously were effective in combating them. AMR is a global problem with particularly dire consequences for Africa which is already grappling with high levels ...of infection in the face of limited resources.
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Version: 2.0 Date: 19.3.2020
This document is a guide for national authorities who are responsible for managing public health responses to COVID-19
The WHO country office for Ghana, began the year 2019 with a 4-day staff retreat at the Busua Beach Resort in the Western Region from 04 to 08 March 2019. The theme for the retreat was ‘Impacting the Health and Lives of the people of Ghana through the Triple Billion Goal”. The staff outlined pri...orities and strategies to strengthen WHO’s contribution to the national health agenda during the year. Working in collaboration with the Ministry of Health/Ghana Health Service and other allied health institutions and stakeholders, the WHO country office, provided support aimed at achieving its
mission which is attaining the highest level of health by the people in the country though its six operational areas which are (i) Communicable Diseases (ii) Non-Communicable Diseases, (iii) Promoting Health through the Life Course (iv), Health Systems, (v) Preparedness, Surveillance and Response (vi) Corporate services and enabling functions.
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Objective: To review the effectiveness of antibiotic stewardship interventions in hospitals in low- and middle-income countries.
Glob Heart . 2020 Oct 13;15(1):69. doi: 10.5334/gh.891.
The Ministry of Health (MoH) of Syria officially declared a cholera outbreak on 10 September 2022, with the majority of cases reported from Aleppo, Deir-ez-Zor and Al-Hasakeh governorates. Since the situation report issued on 26 September 2022, the number of confirmed and suspected cases continues t...o rise. A total of 13 of 14 governorates are now affected, compared with 10 during the last reporting period.
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Nat Commun 9, 5370 (2018). https://doi.org/10.1038/s41467-018-07804-8. Mycobacterium ulcerans is the causative agent of Buruli ulcer, a neglected tropical skin disease that is most commonly found in children from West and Central Africa. Despite the severity of the infection, therapeutic options are... limited to antibiotics with severe side effects. Here, we show that M. ulcerans is susceptible to the anti-tubercular drug Q203 and related compounds targeting the respiratory cytochrome bc1:aa3. While the cytochrome bc1:aa3 is the primary terminal oxidase in Mycobacterium tuberculosis, the presence of an alternate bd-type terminal oxidase limits the bactericidal and sterilizing potency of Q203 against this bacterium. M. ulcerans strains found in Buruli ulcer patients from Africa and Australia lost all alternate terminal electron acceptors and rely exclusively on the cytochrome bc1:aa3 to respire. As a result, Q203 is bactericidal at low dose against M. ulcerans replicating in vitro and in mice, making the drug a promising candidate for Buruli ulcer treatment.
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