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Standard operating procedures (SOP) for the management of tuberculosis in children

National Tuberculosis, Leprosy and Lung Disease Program (NTLD-Program), Kenya Ministry of Health, Kenya (2017) C1

2nd edition. Children with TB comprise about 10-12% of the total TB cases diagnosed in the country. This burden is likely to be higher given the challenges in diagnosing TB in children. The symptoms of TB in children mimic those of other childhood diseases. Children do not readily expectorate and th... more

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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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How COVID-19 is changing the world. Vol.III

UN Department of Economic and Social Affairs (2021) C1

Since the release of the first volume in May 2020, the COVID-19 pandemic has continued to rage around the world. By mid-March, 2021, countries around the globe had reported over 123 million cases—a nearly five-fold increase since this report’s previous volume—and over 2.7 million deaths attrib... more

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Asthma Action Plan - U.S. Centers for disease Control an Prevention

U. S. Centers for Disease Control and Prevention (2024) CC2

Asthma Action Plan Doctor’s Name: Doctor’s Phone Number: Main Emergency Contact: Backup Emergency Contact: Green Zone: No coughing, wheezing, chest tightness, or shortness of breath. Can do usual activities: Every day: Take these medicines, even if you’re not having any symptoms. Av... more

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Interim guidance on COVID-19 Rapid Antigen self-testing to African Union Member States

African Union; Africa CDC Centres for Disease Control and Prevention (2022) C1

This guidance addresses rationale, risk-based scenarios, practical considerations prior to adoption of the self-testing products, quality assurance, safety and ethical considerations, and data management considerations for COVID-19 self-testing. The Africa CDC recommends the use of rapid antigen sel... more

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Coronavirus Disease 2019 (COVID-19) Discharge Instructions

Wolters Kluwer; Clinical Drug Information, Inc. and its affiliates andor licensors (2020) C2

Coronavirus disease 2019 is also known as COVID-19. It is a viral illness that infects the lungs. It is caused by a virus called SARS-associated coronavirus (SARS-CoV-2). This illness was first seen in late 2019 in China and has spread across the world. The signs of COVID-19 are like the flu, and y... more

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Module: Depression

World Health Organization WHO (2017) C_WHO

Overview Learning objectives • Promote respect and dignity for people with depression. • Recognize common symptoms of depression. • Know the assessment principles of depression. • Know the management principles of depression. • Perform an assessment for depression. • Use effective... more

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Factsheet - World Hypertension Day 2023

Pan American Health Organization (PAHO) (2023) C_WHO

Hypertension, or high blood pressure, is a condition which generally has no symptoms and if left untreated, can lead to heart attacks, heart failure, stroke, kidney failure and blindness. Risk factors include older age, overweight or obesity, lack of physical activity, high salt/sodium intake, and h... more

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TOOLKIT: ANGINA

World Heart Federation (2023) CC

This campaign by Servier and the World Heart Federation builds on the success of the USE TO ACT NOW ON ANGINA campaign. In addition to raising awareness of the importance of acting now, this campaign explores some about the common, but less well-known signs of angina, and explains why it’s key to ... more

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Review on palliative care with focus on 18 high tuberculosis priority countries

World Health Organization WHO, Regional Office of Europe (2021) C_WHO

Tuberculosis (‎TB)‎ is, and should be, a curable disease; however, each year significant numbers of patients acquire or develop drug-resistant TB, which has a much lower cure rate. Patients with drug-resistant TB have a high prevalence of symptoms; hence, staff caring for these patients should h... more

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COVID-19 rapid guideline: managing the long-term effects of COVID-19

NICE (2021) CC

This guideline covers identifying, assessing and managing the long-term effects of COVID-19, often described as ‘long COVID’. It makes recommendations about care in all healthcare settings for adults, children and young people who have new or ongoing symptoms 4 weeks or more after the start of a... more

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Epidemiological Update - Dengue - 9 August 2019

World Health Organization, Pan American Health Organization (2019) C_WHO

In the Region of the Americas, between epidemiological week (EW) 1 and EW 52 of 2018, a total of 560,586 cases of dengue were reported (incidence rate of 57.3 cases per 100,000 population), including 336 deaths. Of the total cases, 209,192 (37.3%) were laboratoryconfirmed and 3,535 (0.63%) were clas... more

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Primary Care 101
recommended

Dept. of Health, Republic of South Africa (2013) C1

Symptom-based integrated approach to the adult in primary care. Primary Care 101 is a comprehensive clinical practice guideline that aims to equip nurses and other clinicians to diagnose and manage common adult conditions at primary level. Tb; HIV; Asthma/COPD; cardiovascular disease; diabetes; M... more

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Pediatric Asthma: A Global Epidemic

Serebrisky, D.; Wiznia, A. Annals of Global Health (2019) CC

The global prevalence, morbidity and mortality related to childhood asthma among children has increased significantly over the last 40 years. Although asthma is recognized as the most common chronic disease in children, issues of underdiagnosis and undertreatment persist. There are substantial globa... more

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What is stigma? A guide to understandingmental health stigma

SeeChange (2010) C2

People with mental health conditions are challenged in dealing with the symptoms that result from the condition but are also challenged by the prejudice and stereotypes that result from misconception and misunderstanding about mental health. But what is mental health stigma and why is it a cent... more

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In the wake of the pandemic. Preparing for Long COVID-19

Rajan, S.; et al. World Health Organization WHO, Regional Office of Europe (2021) C_WHO

Policy Brief. Our understanding of how to diagnose and manage Long COVID is still evolving but the condition can be very debilitating. It is associated with a range of overlapping symptoms including generalized chest and muscle pain, fatigue, shortness of breath, and cognitive dysfunction, and the ... more

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Rabies Frequently Asked Questions

National Institute for Communicable Disease NICD (2021) CC

Rabies is a zoonotic, vaccine-preventable viral disease that causes damage to the brain and spinal cord in infected animals and humans. A zoonotic disease is a disease that can be transmitted between animals and humans. Rabies is nearly 100% fatal once symptoms appear.

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Apart Together survey

World Health Organization WHO (2021) C_WHO

Preliminary overview of refugees and migrants self-reported impact of COVID-19 The study surveyed over 30,000 refugees and migrants living in 170 countries. Many of the respondents had fled war or dire economic conditions in their home country only to be faced with the additional challenges posed b... more

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Optimized Supportive Care for Ebola Virus Disease
recommended

World Health Organization WHO (2019) C_WHO

Clinical management standard operating procedures. Ebola virus disease (EVD) is a life-threatening multisystem illness associated with fever and gastrointestinal (GI) symptoms that frequently leads to hypovolaemia, metabolic acidosis, hypoglycaemia, and multi-organ failure. The prolonged 2013–201... more

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The ‘jigsaw puzzle’ approach to building a diagnostic picture of asthma in primary care over time

Ryan, D.; Kocks, J.; Correia de Sousa, J. et al. International Primary Care Respiratory Group (2023) CC

Since there is no single objective diagnostic test for asthma this study suggests an approach of collecting and assembling pieces of clinical information to create a diagnostic picture, like making a jigsaw puzzle. These pieces should include demonstration of symptom and airway variability and/or br... more

Primary Care 101 recommended

Optimized Supportive Care for Ebola Virus Disease recommended

Primary Care 101
recommended

Optimized Supportive Care for Ebola Virus Disease
recommended