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The ongoing global pandemic of SARS-CoV-2 (Covid-19) poses unique diagnostic and clinical management challenges in regions where seasonal epidemic-prone diseases are endemic. Diseases such as dengue, malaria, seasonal influenza, leptospirosis, chikungunya, scrub typhus and bacterial infections often
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This guidance synthesizes current evidence on dengue laboratory testing and diagnostics and provides practical recommendations for laboratories, clinicians, public health officials, and programme managers involved in dengue diagnosis, surveillance, and control, in the context of the global emergency
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PHSM are vital in reducing the risk and scale of infectious disease transmission and lowering hospitalization and deaths. Examples include contact tracing, quarantine and isolation, mask use, ventilation, school or workplace measures, mobility restrictions and travel requirements.
While these mea
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Strengthening global health security to protect the world against future epidemics and pandemics requires well-tested and decentralized capacities for the local detection and rapid containment of outbreaks of infectious disease. For such capacities to translate into effective response actions, ind
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Building true health security in a global age. Findings and recommendations of the Global Council. In landmark findings based on two years of research and convenings around the world, the new report shows that high levels of inequality are linked to outbreaks becoming pandemics and that inequality i
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Developed through broad and inclusive consultation, and aligned with the WHO Global Health Sector Strategies and the Sustainable Development Goals, the framework promotes a people-centred approach and antimicrobial stewardship across 5 key domains: prevention and response, surveillance, research and
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Measles is one of the most contagious diseases for humans. It is caused by a paramyxovirus virus, manifesting as a febrile rash illness. The incubation period for measles usually is 10–14 days (range 7–23 days) from exposure to symptom onset. Initial symptoms (prodrome) generally consist of feve
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A primer for health centers
Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV
recommended
The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and
Adolescents With HIV document is published in an electronic format and updated as relevant changes
in prevention and treatment recommendations occur.
Topics in Antiviral Medicine, volume 33 Issue 2 May 2025
This is the 2025 draft Malawi Guidelines for Syndromic Management of Sexually Transmitted Infections which is yet to be approved by the SMT.
The document “Strategic Framework for Strengthening Cross-Border Surveillance and Information Sharing in Africa” outlines a coordinated strategy developed by Africa CDC to improve public health surveillance and collaboration across national borders in Africa. It addresses the challenge that infe
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Populations affected by emergencies are continually at risk of outbreaks of epidemic-prone diseases and other public health hazards. This operational guidance aims to guide decision-making on when and how to implement and strengthen Early Warning Alert and Response (EWAR) in preparation for and resp
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The document “Guidelines for the Investigation and Control of Disease Outbreaks” provides practical guidance for public health professionals on how to detect, investigate, and manage outbreaks of communicable diseases. It describes the key steps of outbreak investigation, including confirming th
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The document “Strengthening the global architecture for health emergency prevention, preparedness, response and resilience” presents a report by the Director-General of the World Health Organization (WHO) to the World Health Assembly on global efforts to improve preparedness and response to heal
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The document focuses on integrating epidemic risk into the INFORM Global Risk Index, a tool used to assess and compare crisis and disaster risks across countries. It explains how epidemics can significantly impact vulnerability and hazard exposure, and therefore should be systematically included in
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The 2026 appeal seeks nearly US$ 1 billion to respond to 36 emergencies worldwide, including 14 Grade 3 emergencies requiring the highest level of organizational response. These emergencies span sudden-onset and protracted humanitarian crises where health needs are critical.
Recognizing this need and the role of NPHIs in ensuring health security across the continent, the Africa CDC has prioritized the strengthening of NPHIs as a critical pillar of both the New Public Health Order and the Africa CDC Strategic Plan 2023-2027. To aid the realization of this goal, the Afric
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Epidemic Preparedness and Response in Africa | Guidelines for the Decentralization of Laboratory Capacity
recommended
The decentralization of laboratory capacities is a critical strategy for improving epidemic preparedness and response in Africa. Centralized systems often delay case confirmation, hinder timely interventions, and exacerbate the impact of outbreaks, especially in rural and hard-to-reach areas.
Thi
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