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WHO supports Zambia in vaccinating 1 million people in Lusaka against cholera to combat an outbreak that began in October 2017, causing 2,672 cases and 63 deaths. Two million vaccine doses were provided by Gavi. WHO and the Zambia National Public Health Institute are improving water access, sanitati
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on, and hygiene education while training medical staff. Another 1 million people in high-risk areas will be vaccinated later.
more
Le Plan Stratégique Multisectoriel d’Élimination du Choléra en République Démocratique du Congo (2013-2017) vise à réduire l’incidence du choléra à moins d’un cas pour 100 000 habitants. Ce plan repose sur une approche multisectorielle, combinant santé, eau, hygiène et assainissemen
...
t pour enrayer la transmission du choléra.
Il identifie trois types de zones : zones sources (A), zones épidémiques (B) et zones de diffusion (C), chacune nécessitant des interventions adaptées. Les stratégies incluent l’amélioration des infrastructures d’eau potable et d’assainissement, la surveillance épidémiologique, la prévention, la prise en charge médicale et la coordination des actions.
Malgré des progrès dans certaines régions, la mise en œuvre du plan a rencontré des défis, notamment en raison du manque de financements et de la persistance de foyers endémiques dans l'Est du pays. Une coordination nationale et internationale est essentielle pour mobiliser les ressources et atteindre l'objectif d'élimination du choléra en RDC.
more
The study on single-dose cholera vaccine in Zambia evaluates the effectiveness of using a single dose of the oral cholera vaccine (OCV) during a 2016 outbreak in Lusaka. Due to limited vaccine supply, authorities opted for a one-dose emergency campaign instead of the usual two-dose regimen. A matche
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d case-control study was conducted to assess vaccine effectiveness, showing 88.9% short-term protection against cholera. The findings suggest that a single-dose approach can be an effective strategy in outbreak settings, especially when vaccine supplies are constrained. However, further research is needed to determine long-term immunity and effectiveness in young children.
more
The National Integrated Comprehensive Cholera Prevention and Control Plan (2017-2022) outlines Uganda's strategy to reduce cholera cases and mortality by 50% by 2022. The plan focuses on improving access to clean water, sanitation, and hygiene (WASH), strengthening disease surveillance, enhancing ca
...
se management, and implementing oral cholera vaccination (OCV) in high-risk areas. It emphasizes multi-sectoral collaboration, involving government agencies, NGOs, and local communities to ensure a sustainable response. Key interventions include community engagement, improved health services, and better outbreak preparedness, aiming for long-term cholera elimination in Uganda.
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A cólera é uma infecção intestinal provocada por uma bactéria conhecida como Vibrio cholerae. Os principais sintomas desta doença são diarréia e vômitos. Transmissão de cólera ocorre principalmente pelo consumo de alimentos contaminados ou água potável. Neste vídeo descrevemos várias
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técnicas que podem ser utilizadas para ajudar a prevenir a cólera.
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All health-care workers require clear and comprehensive training and education on the importance of hand hygiene, the "My 5 Moments for Hand Hygiene" approach and the correct procedures for handrubbing and handwashing. The following tools and resources are meant to support bridging the knowledge gap
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and for you to adopt and adapt to support local improvement.
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COVID-19 Simulation Exercises Packages
recommended
To support countries’ preparedness effort on the COVID-19 outbreak, the Department of Health Security Preparedness at the WHO headquarters has developed various COVID-19 tabletop exercise (TTX) and Drills (DR) packages .
If you need technical support to implement any of the exercises listed on th
...
is page, please contact your WHO country office or regional office focal point.
more
WHO's Department for HIV, Tuberculosis, Hepatitis and Sexually Transmitted Infections (STIs) has consolidated all existing normative guidance on STIs into a single publication. Structured around 10 chapters that follow the STI prevention and care cascade, the handbook covers primary prevention, synd
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romic management and asymptomatic case identification, diagnostics, treatment, partner management, surveillance, service delivery, and integration within primary health care, community-based clinics, or other platforms (HIV, sexual health, antenatal clinics, etc).
more
The document provides a detailed overview of cholera, including its clinical features, diagnosis, treatment, and prevention. It explains the causes of cholera, its symptoms such as severe diarrhea and dehydration, and the importance of rehydration therapy (oral or intravenous) to reduce mortality. T
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he document also emphasizes public health measures, including access to clean water, proper sanitation, and vaccination, as essential strategies to control and prevent cholera outbreaks. It serves as a comprehensive resource for healthcare professionals managing cholera cases and outbreaks.
more
The Zimbabwe Multi-Sectoral Cholera Elimination Plan (2018–2028) aims to eradicate cholera by improving water, sanitation, and healthcare infrastructure, strengthening disease surveillance, and expanding oral cholera vaccination (OCV). The strategy focuses on five pillars, including public health
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response, WASH, infrastructure, community empowerment, and financing. A multi-sectoral approach involving government, international organizations, and local communities targets cholera hotspots to prevent outbreaks and ensure long-term disease control.
more
Laboratory Biossafety Manual
Prise en charge d’une épidémie de choléra
recommended
Guide pratique à l’usage des médecins, infirmiers, techniciens de laboratoire, auxiliaires de santé, techniciens sanitaires et logisticiens.
Le document est un guide complet pour la gestion des épidémies de choléra, fournissant des protocoles détaillés pour la prévention, l’investigat
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ion des épidémies, le traitement et les mesures de contrôle. Il couvre des aspects essentiels tels que la thérapie de réhydratation, l’assainissement de l’eau, la promotion de l’hygiène et la mise en place de centres de traitement. Conçu pour le personnel médical et non médical, il vise à soutenir une réponse efficace aux épidémies et à réduire la morbidité et la mortalité liées au choléra.
more
Note technique. Les centres de traitement de choléra fournissent des soins hospitaliers aux patients atteints de choléra
pendant les épidémies. Une prise en charge de qualité et l’isolement des patients atteints du choléra sont
essentiels pour prévenir les décès et aider à lutter con
...
tre la propagation de la maladie. Traditionnellement,
ces structures sont appelées centres de traitement du choléra (CTC) et unités de traitement du choléra (UTC).
Les CTC sont généralement de grandes structures mises en place au niveau central (zones urbaines, par
exemple), tandis que les UTC sont des structures plus petites, installées en périphérie (zones périurbaines ou
rurales, par exemple). Les CTC/UTC peuvent être mis en place en tant que structures indépendantes dans
des tentes ou à l’intérieur de bâtiments existants ou dans des unités sanitaires. Quelle que soit la structure,
les principes décrits dans ce document doivent être respectés.
more
The Ethiopia Multi-Sectorial Cholera Elimination Plan (2022-2028) outlines a national strategy to eliminate cholera in Ethiopia by 2028. The plan follows the Global Roadmap to End Cholera by 2030 and is based on six key pillars: Leadership & Coordination, Water, Sanitation & Hygiene (WASH), Surveill
...
ance & Reporting, Use of Oral Cholera Vaccines (OCV), Healthcare System Strengthening, and Community Engagement.
Ethiopia has historically faced recurrent cholera outbreaks due to poor sanitation, unsafe water, and weak health infrastructure. The plan prioritizes high-risk areas (hotspot woredas) and aims to reduce cholera-related mortality by 90% by 2028. It includes efforts to improve WASH conditions, strengthen disease surveillance, enhance rapid response capabilities, expand vaccination campaigns, and integrate cholera control into broader health policies.
The government, in collaboration with international partners such as WHO, UNICEF, and the Global Task Force for Cholera Control (GTFCC), will implement and monitor the plan. The estimated budget for the initiative is $390 million over eight years. Ethiopia aims to achieve zero cholera transmission in hotspot regions, ensuring sustainable public health improvements.
more
The South African Department of Health reports a decline in cholera cases, with only one confirmed case out of 28 suspected cases in the last 10 days as of July 5, 2023. However, authorities urge continued vigilance, emphasizing hygiene, especially during mass gatherings.
Since February 2023, South
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Africa has recorded 1,073 suspected cholera cases, with 198 confirmed cases across five provinces. Gauteng Province is the most affected, with 176 cases, primarily in Hammanskraal, Tshwane. Other affected provinces include Free State, North West, Limpopo, and Mpumalanga.
The outbreak has resulted in 47 deaths, with four new suspected deaths reported in the Free State. The majority of confirmed cases are in individuals aged 41-50 years, and 52% of cases are female.
The health department continues preventive efforts through health education and targeted case-finding. Authorities also stress the importance of clean water and hygiene compliance in initiation schools to prevent further outbreaks.
more
The UNHCR Cholera Response Plan (October 2022 – March 2023) outlines efforts to combat the cholera outbreak in Lebanon, which was declared in October 2022. The plan, led by the Ministry of Public Health with support from UNHCR, WHO, UNICEF, and NGOs, focuses on prevention, response, and surveillan
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ce. Key actions include oral cholera vaccination campaigns, rapid diagnostics, strengthening healthcare facilities, and improving hygiene and sanitation in high-risk refugee settlements and collective shelters. The response also emphasizes risk communication and community engagement to raise awareness and ensure early detection. The plan targets 120,000 individuals and requires $8.5 million in funding to provide life-saving support and containment measures.
more
The key actions, activities, and approaches in this document are organized within each of the 5Cs (see Table 1 in the PDF) and those of the Strategic preparedness and response plan (SPRP) pillars as follows:
National action plan key activities, prioritized for the current context and the current
...
understanding of the threat of SARS-CoV-2
A. Transition from emergency response to longer term COVID-19 disease management.
B. Integrate activities into routine systems.
C. Strengthen global health security.
Special considerations for fragile, conflict-affected and vulnerable (including humanitarian) settings
WHO global and regional support to Member States to implement their national action plans
Key guidance documents for reference
This is a living document that will be updated to incorporate new technical guidance in response to the evolving epidemiological situation. National plans should be implemented in accordance with the principles of inclusiveness, respect for human rights, and equity.
more
The response to a cholera outbreak must focus on limiting mortality and reducing the spread of the disease. It should be comprehensive and multisectoral, including epidemiology, case management, water, sanitation and hygiene, logistics, community engagement and risk communication. All efforts must b
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e well coordinated to ensure a rapid and effective response across sectors.
This document provides a framework for detecting and monitoring cholera outbreaks and organizing the response. It also includes a short section linking outbreak response to both preparedness and long-term prevention activities.
more
Peripheral arterial disease (PAD) in the legs or lower extremities is the narrowing or blockage of the vessels that carry blood from the heart to the legs. It is primarily caused by the buildup of fatty plaque in the arteries, which is called atherosclerosis. PAD can happen in any blood vessel, but
...
it is more common in the legs than the arms.
more
Two decades of epidemiological research shows that silent cerebrovascular disease is common and is associated with future risk for stroke and dementia. It is the most common incidental finding on brain scans. To summarize evidence on the diagnosis and management of silent cerebrovascular disease to
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prevent stroke, the Stroke Council of the American Heart Association convened a writing committee to evaluate existing evidence, to discuss clinical considerations, and to offer suggestions for future research on stroke prevention in patients with 3 cardinal manifestations of silent cerebrovascular disease: silent brain infarcts, magnetic resonance imaging white matter hyperintensities of presumed vascular origin, and cerebral microbleeds. The writing committee found strong evidence that silent cerebrovascular disease is a common problem of aging and that silent brain infarcts and white matter hyperintensities are associated with future symptomatic stroke risk independently of other vascular risk factors. In patients with cerebral microbleeds, there was evidence of a modestly increased risk of symptomatic intracranial hemorrhage in patients treated with thrombolysis for acute ischemic stroke but little prospective evidence on the risk of symptomatic hemorrhage in patients on anticoagulation. There were no randomized controlled trials targeted specifically to participants with silent cerebrovascular disease to prevent stroke. Primary stroke prevention is indicated in patients with silent brain infarcts, white matter hyperintensities, or microbleeds. Adoption of standard terms and definitions for silent cerebrovascular disease, as provided by prior American Heart Association/American Stroke Association statements and by a consensus group, may facilitate diagnosis and communication of findings from radiologists to clinicians.
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