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1
Scientists have known for more than half a century that patients could develop resistance to the drugs used to treat them. Alexander Fleming, who is credited with creating the first antibiotic, penicillin, in 1928, cautioned of the impending crisis
...
while accepting his Nobel prize in 1945: “There is the danger that the ignorant man may easily underdose himself and by exposing his microbes to non-lethal quantities of the drug make them resistant.” Since then antibiotics have proved one of the most effective interventions in human medicine. Sadly, the overuse and misuse of this precious resource have brought us to a global crisis of antimicrobial resistance (AMR). To address this crisis nearly seven decades after Fleming’s lecture the first UN general assembly meeting on drug resistance bacteria was convened in September 2017.
more
In this entry we are looking at smoking, alcohol consumption and the use of illicit drugs. We are studying who is using these substances, how their use has changed over time,
...
and we are presenting the estimates of their impact on health. Collectively, smoking, alcohol and illicit drug use kills 11.8 million people each year. This is more than the number of deaths from all cancers
more
Non-communicable diseases (NCDs) are the second common cause of death in sub-Saharan Africa (SSA) accounting for about 35% of all deaths, after a composite
...
of communicable, maternal, neonatal, and nutritional diseases. Despite prior perception of low NCDs mortality rates, current evidence suggests that SSA is now at the dawn of the epidemiological transition with contemporary double burden of disease from NCDs and communicable diseases. In SSA, cardiovascular diseases (CVDs) are the most frequent causes of NCDs deaths, responsible for approximately 13% of all deaths and 37% of all NCDs deaths. Although ischemic heart disease (IHD) has been identified as the leading cause of CVDs mortality in SSA followed by stroke and hypertensive heart disease from statistical models, real field data suggest IHD rates are still relatively low. The neglected endemic CVDs of SSA such as endomyocardial fibrosis and rheumatic heart disease as well as congenital heart diseases remain unconquered. While the underlying aetiology of heart failure among adults in high-income countries (HIC) is IHD, in SSA the leading causes are hypertensive heart disease, cardiomyopathy, rheumatic heart disease, and congenital heart diseases. Of concern is the tendency of CVDs to occur at younger ages in SSA populations, approximately two decades earlier compared to HIC. Obstacles hampering primary and secondary prevention of CVDs in SSA include insufficient health care systems and infrastructure, scarcity of cardiac professionals, skewed budget allocation and disproportionate prioritization away from NCDs, high cost of cardiac treatments and interventions coupled with rarity of health insurance systems. This review gives an overview of the descriptive epidemiology of CVDs in SSA, while contrasting with the HIC and highlighting impediments to their management and making recommendations.
more
Nature Reviews Microbiology Vol. 17 (2019)pp.51-62
Antimicrobial susceptibility testing (AST) technologies help to accelerate the
initiation of targeted antimicrobial therapy for patients with infections
...
and could potentially
extend the lifespan of current narrow- spectrum antimicrobials. Although conceptually new and
rapid AST technologies have been described, including new phenotyping methods, digital
imaging and genomic approaches, there is no single major, or broadly accepted, technological
breakthrough that leads the field of rapid AST platform development
more
INEE pocket gu ide to inclusive education.
This guide is aimed at anyone working to provide, manage or support education services in emergencies and complements the INEE Minimum Standards.
The
...
Pocket Guide to Inclusive Education outlines useful principles for an inclusive education approach in emergencies and provides advice for planning, implementing and monitoring. The guide also looks at the issue of resistance to inclusion, and highlights ways in which organisations can support their emergency staff to develop more inclusive education responses. Available in Arabic, English, Indonesia, French, Spanish
more
Intimate Partner Violence and Interruption to Contraceptive Use
Kerry L.D. MacQuarrie, Lindsay Mallick &; Sunita Kishor
Rockville, Maryland, USA: ICF International
(2016)
DHS Analytical Studies No. 57
DHS Working Papers No. 101
Women’s empowerment, HIV testing, birth in past five years, Tanzania
Census Report Volume 4-C
The 2014 Myanmar Census provided the opportunity to measure maternal mortality. The questions on deaths in households during the twelve months prior to the Census were included in the questionnaire, as well as questions necessary to estimate maternal mortality indicator ... s. more
The 2014 Myanmar Census provided the opportunity to measure maternal mortality. The questions on deaths in households during the twelve months prior to the Census were included in the questionnaire, as well as questions necessary to estimate maternal mortality indicator ... s. more
Preventing Suicide: A Technical Package of Policy, Programs, and Practices
Stone, D.; K. Holland, B. Bartholow, et al.
Centers for Disease Control and Prevention CDC
(2017)
C_CDC
This technical package represents a select group of strategies based on the best available evidence to help communities and states sharpen their focus on prevention activities with the greatest pote
...
ntial to prevent suicide
more
Tanzania HIV/AIDS and Malaria Indicator Survey 2011-2012
Tanzania Commission for AIDS (TACAIDS); Zanzibar AIDS Commission (ZAC); National Bureau of Statistics (NBS); et al.
ICF International, et al.
(2013)
C1
Introduction
Chapter A.2
Health Policy Plan (2017) 32 (5): 603-612; 10 pp. 318 kB
BMJ Global Health2019;4:e001504. doi:10.1136/bmjgh-2019-00150
Including Therapeutic Food, Dietary Vitamin and Mineral Supplementation - 2nd edition
published in: Viruses 2016, 8, 161
