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Target product profile for a rapid test for diagnosis of Buruli ulcer at the primary health-care level

World Health Organization WHO (2022) C_WHO
In 2009, WHO’s Second International Conference on Buruli Ulcer Control and Research resolved to strengthen the capacity of national laboratories to confirm cases of the disease, but advised that “efforts are still needed to develop simple diagnostic tools usable in the field as well as disabilit... more
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Africa, WASH, and the Millennium Development Goals: A Local Systems Case Study of How South Africa Achieved MDG Target 7c

Muller, Helgard et al. USAID (2017) C1
Democratic dispensation in 1994 created a political and social platform that reshaped life in South Africa. There was a surge in common belief that the inequity and wrong of Apartheid should and could be rectified. Equity of access to water and sanitation were obvious targets for improvement. In 199... more
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Target product profile for a test for rhodesiense human African trypanosomiasis diagnosis usable in peripheral health facilities

World Health Organization WHO (2021) C_WHO
The development of this target product profile (TPP) was led by the WHO Department of Control of Ne- glected Tropical Diseases (NTD) following standard WHO guidance for TPP development. In order to identify and prioritize diagnostic needs, a WHO NTD Diagnostics Technical Advisory Group (DTAG) was... more
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Point-of-care tests for sexually transmitted infections: target product profiles

World Health Organisation (WHO) (2023) C_WHO
Despite the development of point-of-care diagnostic tests for syphilis, chlamydia, gonorrhoea, and trichomoniasis, none comply with all WHO criteria. This analysis overviews landscape analyses of point-of-care diagnostic technologies for Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vagi... more
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Target product profiles for animal plasma-derived antivenoms: antivenoms for treatment of snakebite envenoming in sub-Saharan Africa

World Health Organisation (WHO) (2023) C_WHO
This publication describes the first WHO public-benefit Target Product Profiles (TPPs) for snakebite antivenoms. It focuses on antivenoms for treatment of snakebite envenoming in sub-Saharan Africa. Four TPPs are described in the document: Broad spectrum Pan-African polyvalent antivenoms: products ... more
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Enhanced COVID-19 Surveillance at the Community Level in Africa

African Union; Africa CDC Centres for Disease Control and Prevention (2021) CC
The strategy recommends that AU Member States should enhance, where feasible, existing COVID-19 surveillance to include: Community-based surveillance to detect symptomatic cases early for treatment and to avert viral transmission; Sentinel surveillance in high-risk populations to detect ... more
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2019 Antibacterial agents in clinical development: an analysis of the antibacterial clinical development pipeline
recommended

World Health Organization WHO (2019) C_WHO
Of the 50 antibiotics in the pipeline, 32 target WHO priority pathogens but the majority have only limited benefits when compared to existing antibiotics. Two of these are active against the multi-drug resistant Gram-negative bacteria, which are spreading rapidly and require urgent solutions. Gr... more
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The medicinal plants of Myanmar

DeFilipps, Robert A.; Krupnick, Gary A. (2018) CC
A comprehensive compilation is provided of the medicinal plants of the Southeast Asian country of Myanmar (formerly Burma). This contribution, containing 123 families, 367 genera, and 472 species, was compiled from earlier treatments, monographs, books, and pamphlets, with some medicinal uses and pr... more
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Monitoring the elimination of human African trypanosomiasis at continental and country level: Update to 2018

Franco, JR.; Cecchi, G.; Priotto, G.; Paone, M.; Diarra, A. et al. (2020) CC
Over the past twenty years, huge efforts made by a broad coalition of stakeholders curbed the last epidemic and brought the disease to the brink of elimination. In this paper, the latest figures on disease occurrence, geographical distribution and control activities are presented. Strong evidence in... more
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Target product profile for a point-of-care diagnostic test for dermal leishmaniases

World Health Organization WHO (2022) C_WHO
In 2007, the Sixtieth World Health Assembly adopted resolution WHA60.13 on control of leishmaniasis, urging Member States, among other actions: to strengthen prevention, active detection and treatment of cases of both cutaneous and visceral leishmaniasis in order to decrease the disease burde... more
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Diagnostic target product profiles for monitoring, evaluation and surveillance of schistosomiasis control programmes

World Health Organization WHO (2021) C_WHO
Health ministries currently lack effective tools for monitoring and evaluation of schistosomiasis control programmes. Egg detection can be used, but the cost, challenges of obtaining samples, and the need for trained personnel and equipment limit the frequency of monitoring. The purpose of this TPP ... more
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World Health Statistics 2021: monitoring health for the SDGs
recommended

World Health Organization (WHO) (2021) C_WHO
The report presents the latest data on more than 50 health-related Sustainable Development Goal and "triple billion" target indicators. The 2021 edition includes preliminary estimates for global excess deaths attributable to COVID-19 for 2020 and the state of global and regional health trends from 2... more
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World Health Statistics 2021: monitoring health for the SDGs. A visual summary
recommended

World Health Organization (WHO) (2021) C_WHO
The report presents the latest data on more than 50 health-related Sustainable Development Goal and "triple billion" target indicators. The 2021 edition includes preliminary estimates for global excess deaths attributable to COVID-19 for 2020 and the state of global and regional health trends from 2... more
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Interim Guidlines for the clinical management of diabetes in Jamaica

Ministry of Health and Wellness (2020) CC2
Diabetes mellitus, also called diabetes, is a chronic metabolic condition in which the hormone insulin is not produced by the pancreas in sufficient quantities or is not utilized effectively by the body to control blood glucose levels. As a result, blood glucose levels are abnormally high (hypergl... more
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Guideline for the pharmacological treatment of hypertension in adults
recommended

World Health Organization WHO (2021) C_WHO
The recommendations cover the level of blood pressure to start medication, what type of medicine or combination of medicines to use, the target blood pressure level, and how often to have follow-up checks on blood pressure. In addition, the guideline provides the basis for how physicians and other h... more
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Guidelines for the Diagnosis and Treatment of Malaria in Somalia

Federal Government of Somalia, Puntland & Somaliland, Zonal NMCPsMoH (2016) C1
The main objective of the malaria prevention and control programme in Somalia is to prevent mortality and reduce morbidity due to malaria. The groups most vulnerable to the disease, children aged under 5 years and pregnant women, are especially targeted. Effective case management - early diagnosis a... more
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The Impact of Climate Change on Health: Reducing Risks and Increasing Resilience in the Era of COVID-19

Machalaba; C.; Bouley, T. A.; Nunziata, K. R.; et al. (2021) C1
The climate crisis has many consequences – among them widespread health impacts that will lead to immense societal, ecological, and economic harm. Over the past two decades multiple large-scale reviews on climate change and health have made clear the need for a multi-sectoral approach to target t... more
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Public health guidance on screening and vaccination for infectious diseases in newly arrived migrants within the EU/EEA

European Centre for Disease Prevention and Control (2018) C1
The main objective of this guidance is to provide scientific advice, based on an evidence-based assessment of targeted public health interventions, to facilitate effective screening and vaccination for priority infectious diseases among newly arrived migrant populations to the EU/EEA. It is intended... more
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Preferred product characteristics for personal protective equipment for the health worker on the frontline responding to viral hemorrhagic fevers in tropical climates
recommended

World Health Organization (2018) C_WHO
The scope of this PPC document is to serve as a guide to address the unmet public health need for a PPE system that protects the HW-F in tropical climate s while caring for patients and providing heavy duty essential health services. The characteristics described in this guidance are targeted fo... more
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Operational guide: use of referral laboratories for the analysis of foodborne hazards in the Pacific

World Health Organisation (WHO) (2023) C_WHO
The Operational guide: use of referral laboratories for the analysis of foodborne hazards in the Pacific aims to strengthen the food analysis capacity of Pacific Island countries and areas by identifying national and reference laboratories capable of testing for priority foodborne hazards. The Pacif... more