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Regulatory guidance for assessment and management of applications for marketing authorization of oxytocin

World Health Organization WHO (2021) C_WHO

Pharmaceutical regulators are at the forefront of ensuring that only safe and effective medicines are authorized and available in the market. This document builds on the recommendations in the above publication and has been prepared to specifically assist national medicines regulatory authorities to... more

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Conceptual and Operational Framework of Onchocerciasis Elimination with Ivermectin Treatment

World Health Organization WHO; African Programme for Onchocerciasis Control APOC (2010) C_WHO

Onchocerciasis used to be an important public health problem in Africa, with over 37 million people infected and millions suffering from debilitating skin disease, terrible itching, impaired vision and blindness. But the epidemiological situation has improved dramatically over the last two decades.... more

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International Development Association Project Paper on a Proposed Additional Gran

International Development Association World Bank (2016) C1

IN THE AMOUNT OF SDR 21.8 MILLION (US$30 MILLION EQUIVALENT) WITH AN ADDITIONAL GRANT FROM THE GLOBAL FINANCING FACILITY (GFF) IN THE AMOUNT OF US$ 10 MILLION TO THE DEMOCRATIC REPUBLIC OF CONGO FOR A HUMAN DEVELOPMENT SYSTEMS STRENGTHENING PROJECT

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A Second Revolution: Thirty years of child rights, and the unfinished agenda

Terre des hommes, Save the Children, Plan International, SOS Children's Villages International, World Vision, ChildFund Alliance (2019) C2

The report showed commitments made three decades ago to protect the rights of children remain unfulfilled for millions. Violence still affects countless children. Discrimination based on age, gender, disability, sexual orientation and religion harms children worldwide. Key factors include a lack ... more

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Republic of Congo: Population Movement - Emergency Plan of Action (EPoA) MDRCG016

International Federation of Red Cross And Red Crescent Societies IFRC (2019) C1

On Sunday 16th December 2018, some villages in the Province of Mai-Nambiar, Democratic Republic of Congo, neighboring the district of Makotimpoko in the Republic of Congo (CongoBrazzaville) were affected by inter-ethnic conflict between the Banunu and the Batende. The fighting has resulted in 400 fa... more

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State of the Climate in Africa 2020

World Meteorological Organization (2021) C2

Climate change triggers mounting food insecurity, poverty and displacement in Africa

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The distinctive role of the Catholic Church in development and humanitarian response: 7 ways the Church makes a difference

Catholic Agency for Overseas Development CAFOD (2021) CC

7 Febr. 2021 As COVID-19 continues to wreak havoc in countries – decimating people’s livelihoods, and leaving health systems struggling to provide healthcare and vaccines for the entire population - governments and donors should look to the Church as a partner. The essential Church networks, tr... more

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Burden sharing or burden shifting? - HIV and TB

Médecins Sans Frontières (MSF) (2019) C1

MSF provides treatment for HIV and tuberculosis (TB) in more than 20 countries around the world. The report Burden sharing or burden shifting? How the HIV/TB response is being derailed examines the situation in nine countries where MSF runs programmes: Central African Republic, Democratic Republic ... more

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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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South Sudan Situation - Responding to the needs of displaced South Sudanese and refugees, Supplementary Appeal January - December 2018

UN High Commissioner for Refugees (2018) C1

The refugee exodus from South Sudan continues at an alarming rate, even as the crisis is entering its fifth year. Close to 2.4 million South Sudanese have fled to neighbouring countries mostly to Uganda—the largest host country in sub-Saharan Africa—followed by Sudan, Ethiopia, Kenya, the Democr... more

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Child soldiers international annual report 2016-17

Child Soldiers International CSI (2017) C1

Armed conflict continues to tear apart communities across the world. From Boko Haram’s abducted ‘brides’ and Islamic State’s ‘Caliphate Cubs’, to the countless others exploited by armed groups in Democratic Republic of Congo, South Sudan and Afghanistan, many taking part in the world’s... more

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Ensuring health security in the African region - Emergency preparedness and response flagship programmes

World Health Organization WHO, Regional Office of Africa (2022) C_WHO

The World Health Organization Regional Office for Africa (WHO AFRO), in accordance with recommendations from various WHO committees, has developed three flagship programmes to support Member States in the African region to prepare for, detect and respond to public health emergencies. They are the re... more

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Ethiopia: COUNTRY PROGRESS REPORT ON THE HIV RESPONSE 2014

Ministry of Health, Federal Democratic Republic of Ethiopia (2014) C1

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HIV-related Needs in Internally Displaced Persons and Other Conflict-affected Populations: A Rapid Situation Assessment Tool
recommended

UNHCR; UNAIDS (2007) CC

This assessment tool for HIV and internally displaced persons (IDPs) is an outcome of multisectoral, multi-agency assessment missions in Côte d’Ivoire, the Democratic Republic of Congo, Nepal and the United Nations High Commissioner for Refugees (UNHCR) first global consultation on HIV and inter... more

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Overview of Mtoto Mwerevu Stunting Reduction Toolkit

IMA World Health (2021) CC

The Mtoto Mwerevu Stunting Reduction Toolkit is a resource for government and organisations involved in addressing stunting and broader nutrition issues in Tanzania. The toolkit was developed in conjunction with the Government of Tanzania (GoT) with funding from UK Aid as part of the Addressing Stun... more

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Actioning the Emergency Medical Teams’ initiative in the WHO African Region: strategic paper

World Health Organisation (WHO) (2023) C_WHO

Emergency medical teams (EMT) are first response health care providers – doctors, nurses, paramedics, and others – during outbreaks and emergencies or disasters, working with governments, charities such as nongovernmental organizations (NGOs), armies, and international organizations such as the ... more

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Business case for WHO immunization activities on the African continent 2018-2030

World Health Organization (WHO) (2018) C_WHO

The Global Vaccine Action Plan (GVAP) 2011-2020, endorsed by Member States during the May 2012 World Health Assembly, has set ambitious targets to improve access to immunization and tackle vaccine-preventable diseases. This responsibility has been translated into firm commitments in February 2016, t... more

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Protect the promise: 2022 progress report on the every woman every child global strategy for women’s, children’s and adolescents’ health (2016–2030)

World Health Organisation (WHO) (2022) C_WHO

This global progress report attempts to lay the groundwork for the kind of accelerated action needed. Section 1 presents key data, trends and developments in women’s, children’s and adolescents’ health and well-being. That is followed in Section 2 by a deeper dive into the impact of the COVID-... more

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Financing Global Health 2014: Shifts in Funding as the MDG Era Closes

Institute for Health Metrics and Evaluation (2015) CC

Financing Global Health 2014 is the sixth edition of this annually produced report on global health financing. As in previous years, this report captures trends in development assistance for health (DAH) and government health expenditure (GHE). Health financing is one of IHME’s core research areas... more

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Community health workers at the dawn of a new era: 9. CHWs’ relationships with the health system and communities

Karen LeBan , Maryse Kok and Henry B. Perry Health Research Policy and Systems (2021) CC

This is the ninth paper in our series, “Community Health Workers at the Dawn of a New Era”. Community health workers (CHWs) are in an intermediary position between the health system and the community. While this position provides CHWs with a good platform to improve community health, a major cha... more

HIV-related Needs in Internally Displaced Persons and Other Conflict-affected Populations: A Rapid Situation Assessment Tool recommended

HIV-related Needs in Internally Displaced Persons and Other Conflict-affected Populations: A Rapid Situation Assessment Tool
recommended