Journal of Tuberculosis Research, 2017, 5, 189-200
Background: In Benin, little is known about the influence of both gender and
HIV-status on diagnostic patterns and treatment outcomes of Tuberculosis
(TB) patients. Objective: To assess whether differences in gender and HIV
status affect diagn...ostic patterns and treatment outcomes of TB patients. Methods:
Retrospective cohort study of patients registered in 2013 and 2014 in
the three largest TB Basic Management Units in south Benin. Results: Of 2694
registered TB patients, 1700 (63.1%) were male. Case notification rates were
higher in males compared with females (96 vs 53/100,000 inhabitants). The
male to female ratio was 1:1 in HIV positive patients, but was 2:1 among HIV
negative cases. In HIV-positive patients, there were no differences in TB types
between men and women. In HIV-negative patients, there were significantly
higher proportions of females with clinically diagnosed pulmonary TB (p =
0.04) and extrapulmonary TB (p < 0.001). Retreatment TB was 4.65 times
higher amongst males compared with females. For New bacteriologically confirmed
pulmonary TB, no differences were observed in treatment outcomes
between genders in the HIV positive group; but significantly more unfavorable
outcomes were reported among HIV negative males, with higher rates of
failure (p < 0.001) and loss-to-follow up (p = 0.02). Conclusion: The study
has shown that overall TB notification rates were higher in males than in females
in south Benin, with more females co-infected with HIV. Unfavorable outcomes were more common in HIV-negative males.
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PLOS ONE | DOI:10.1371/journal.pone.0172392 February 16, 2017
Техническая записка;
Целью настоящей Технической записки является оказание содействия кандидатам наполучение грантов Глобального фонда при рассмотрении ...возможностей включения программ, направленных на устранение барьеров, обусловленных нарушением прав человека и гендерным неравенством, которые препятствуют получению услуг по профилактике, диагностике и лечению туберкулеза (ТБ), в запросы на финансирование, а также оказание помощивсем заинтересованным сторонам в том, чтобы программы по борьбе с ТБ обеспечивали продвижение и защиту прав человека и гендерного равенства.
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