Sustainability Science (2019) 14:1343–1354
The objective of the study was the validation and implementation of GeneXpert MTB/RIF for routine use in the rapid detection of tuberculosis and sensitivity to rifampicin in clinical samples; for this, 1592 respiratory samples were collected and analyzed in the laboratory of Instituto Nacional de In...vestigación en Salud Pública Guayaquil. The analysis of the results of GeneXpert in comparison with smear microscopy showed an initial sensitivity of 99.8% and specificity of 93.2%; The analysis of discrepancies using the results of the culture as a reference method showed that the GeneXpert results considered false negatives turned out to be true negatives, the same happens with the false positives that correspond to true positives. Recalculated the sensitivity and specificity of the GeneXpert was 99.8% and 100% correspondingly. The comparison with the drugs susceptibility test showed a sensitivity of 91.4% and a specificity of 95.5% for the GeneXpert MTB/RIF system. It is concluded that the implementation of the GeneXpert system allows solution to certain problems associated with the application of conventional diagnostic methodologies, decreasing the waiting times, and increasing the sensitivity and specificity in the diagnosis of drug-resistant tuberculosis, thus generating a valuable opportunity for early diagnosis.
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International Journal for Quality in Health Care, 2018, 30(9), 724–730
Promoting hand hygiene in a neonatal intensive care unit.
Suchtmedizinische Reihe
Band 4
Accessed: 14.03.2019
Experiences from Indonesia, Kenya, Uganda and Ukraine
Expert Consensus Validation 2018.
This innovative approach aimed at improving and facilitating the screening, prescribing and monitoring of drug therapy for older patients, is currently being further developed in the area of Clinical Pharmacology at the University of Heidelberg in Mannheim. This ap...proach represents another advance in worldwide research efforts aimed at adding a new dimension to already-existing classification systems and negative listings of potentially inappropriate medications for the elderly.
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Research Article
PLOS ONE | https://doi.org/10.1371/journal.pone.0192791 February 15, 2018
Research Article
PLOS ONE | https://doi.org/10.1371/journal.pone.0190785 January 10, 2018
PLOS ONE | https://doi.org/10.1371/journal.pone.0193145 February 22, 2018 1 / 13
PLOS Medicine | https://doi.org/10.1371/journal.pmed.1002514 March 1, 2018
Supplement Article
J Acquir Immune Defic Syndr Volume 78, Supplement 1, August 15, 2018 www.jaids.com
J Acquir Immune Defic Syndr Volume 78, Supplement 1, August 15, 2018
Gac Méd Caracas 2018;126(1):52-78
Responsibilidad Social Institucional (RSI)
Policy Brief
published: 16 March 2018 doi: 10.3389/fpubh.2018.00069
Journal of Virus Eradication 2018; 4 (Supplement 2): 33–39