El propósito de esta guía es brindar orientaciones clínicas actualizadas en TB/VIH con énfasis en aspectos de diagnóstico, incluidas nuevas técnicas, así como de tratamiento vigente, sin perder de vista un enfoque de salud pública. Al recopilar y consolidar en una sola guía las últimas rec...omendaciones de la Organización Mundial de la Salud en el tema, se busca elaborar un documento de referencia y consulta frecuente, que unifique y estandarice el manejo de la coinfección TB/VIH de manera integral en establecimientos de salud con base en el principio de “dos enfermedades, un solo paciente”. También busca sustentar la actualización de normas y guías nacionales sobre la coinfeccion y complementar el trabajo coordinado que debe existir entre los programas de prevencion y control de TB y VIH a todo nivel en el marco las doce actividades de colaboración TB/VIH recomendadas internacionalmente.
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The purpose of this guide is to provide updated clinical guidance on TB/HIV, with an emphasis on diagnostic aspects—including new techniques—as well as current treatment, while maintaining a public health approach. By compiling and consolidating the latest World Health Organization recommendatio...ns on the subject into a single guide, the aim is to create a reference and consultation document that is frequently used, and that unifies and standardizes the comprehensive management of TB/HIV co-infection in healthcare facilities based on the principle of “two diseases, one patient.” It also seeks to support the updating of national standards and guidelines on co-infection and to complement the coordinated work that must exist between TB and HIV prevention and control programs at all levels, within the framework of the twelve internationally recommended TB/HIV collaborative activities.
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Anopheles stephensi is an invasive mosquito species which has been found spreading across Africa. While this species presents a new challenge for malaria control on the continent, its surveillance and management have been ongoing in Asia for many years. This document aims to summarize key lessons fr...om 3 countries – India, the Islamic Republic of Iran and Sri Lanka – that have been working to control An. stephensi. It is hoped that their experiences and insights will be valuable for countries encountering An. stephensi for the first time.
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Clinical Pharmacology: Advances and Applications, 2025:17 29–47
Tropical Medicine and Health (2023) 51:29
Vector control, alongside case management, remains the most effective approach to controlling and eliminating malaria. Key interventions, such as indoor residual spraying (IRS) and long-lasting insecticidal nets (LLINs), have significantly reduced malaria transmission in many African countries. This... has enabled some countries to transition from the control phase to the elimination phase.
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Fragile Beginnings. The Fragile Beginnings series examines the growing body of research on the unique vulnerabilities of children: in utero and at birth, during infancy and childhood and throughout adolescence. Its purpose is to enable evidence-based advocacy and action on children’s environmental... health
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Malaria Journal (2021) 20:190
Ce document présente les lignes directrices actualisées pour la prise en charge du paludisme en République Centrafricaine. Il s’appuie sur les recommandations de l’OMS et vise à améliorer le diagnostic, le traitement et la prévention de la maladie, particulièrement chez les femmes enceint...es et les enfants de moins de cinq ans. Il insiste sur l’utilisation des tests de diagnostic rapide (TDR) et des combinaisons thérapeutiques à base d’artémisinine (CTA). Il définit aussi les traitements selon la gravité du paludisme et la condition du patient, et propose une approche préventive à travers le traitement préventif intermittent (TPI) chez les femmes enceintes et les nourrissons. Le document détaille également le rôle des agents de santé et des relais communautaires dans la stratégie nationale de lutte contre le paludisme.
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The document “Malaria Prophylaxis for Travellers: Guideline for Healthcare Workers” (2019) from Sri Lanka provides guidance for healthcare providers on preventing malaria among travelers to endemic areas.
It explains that since Sri Lanka was certified malaria-free in 2016, the main risk comes f...rom imported cases, mostly Sri Lankan travelers. The document emphasizes assessing travelers’ risk, advising on mosquito bite prevention, and prescribing appropriate chemoprophylaxis like chloroquine, mefloquine, atovaquone-proguanil, or doxycycline depending on destination and traveler profile.
It highlights that children, pregnant women, and immunocompromised individuals are particularly at risk, and stresses adherence to medications and protective measures. Special instructions are given on handling missed doses, long-term prophylaxis, and managing side effects. Overall, the guideline aims to maintain Sri Lanka’s malaria-free status by preventing reintroduction through well-informed traveler care.
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The Manual for Indoor Residual Spraying in Urban Areas for Aedes aegypti Control is intended not only for operational personnel and middle and senior management of programs responsible for the prevention and control of Aedes-borne diseases, but also for the academic community involved in Aedes resea...rch, private pest control personnel, and the general public.
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Manual para aplicar rociado residual intradomiciliario en zonas urbanas para el control de Aedes aegypti no solo está dirigido al personal operativo y los mandos medios y directivos de los programas de prevención y control de las enfermedades transmitidas por Aedes, sino también a la comunidad ac...adémica relacionada con la investigación operativa sobre RRI-Aedes, a los controladores de plagas privados y al público en general.
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O Manual para aplicação de borrifação residual em áreas urbanas para o controle do Aedes aegypti não se dirige apenas ao pessoal operacional e aos gerentes e gestores de nível médio dos programas de prevenção e controle das doenças transmitidas pelo Aedes, mas também à comunidade acadê...mica ligada à pesquisa operacional sobre BRI-Aedes, aos controladores de pragas privados e ao público em geral.
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This policy brief presents a summary of current evidence on vulnerability to TB and proposes interventions for equitable, person-centred, and human rights-based TB prevention and care. It aligns with WHO policies and guidance on TB prevention and screening, management of TB and comorbidities, access... to health care, universal health coverage, determinants of TB, TB-associated impairment and disability, social protection, as well as ethics, equity and human rights.
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Diabetes is an increasingly prevalent yet under-recognised health crisis in Africa, driven by demographic and socioeconomic transitions. In 2021, 24 million adults in the region were living with diabetes, and this figure is expected to increase by 129% by 2045.
The Manual for Parasitological Surveillance in Prevention of Reintroduction or Re-establishment of Malaria in Sri Lanka (2019) provides guidelines to health professionals on how to conduct effective malaria surveillance to prevent the reintroduction of the disease in Sri Lanka, which was certified m...alaria-free in 2016.
The manual outlines strategies for active and passive case detection, laboratory diagnosis, case investigation, foci investigation, and follow-up measures. It emphasizes targeted screening of high-risk populations, including travelers and migrant workers, and explains the importance of prompt reporting, accurate parasitological confirmation, and coordination between healthcare levels. The overall goal is to maintain Sri Lanka’s malaria-free status by ensuring early detection and rapid response to any imported or locally suspected malaria cases.
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La presente “Pautas de tratamiento en casos de malaria en la República Bolivariana de Venezuela” es un esfuerzo del Ministerio del Poder Popular para la Salud (MPPS), con el apoyo de la Organización Panamericana de la Salud / Organización Mundial de la Salud (OPS / OMS). En su elaboración ha...n participado expertos en malaria de las sociedades médicas, de los principales hospitales nacionales y estatales, quienes durante meses han realizado reuniones de trabajo, de campo, revisiones bibliográficas y actualizaciones terapéuticas, para finalmente, por consenso, aprobar la presente pauta. Este documento busca resumir de manera clara, la forma correcta de tratar a los pacientes con malaria o paludismo en todo el territorio nacional. De esta forma se busca que se estandaricen los pasos a seguir desde que se sospecha de un caso de malaria, el diagnóstico, el tratamiento, el seguimiento y alta de un paciente.
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La Stratégie Nationale de Plaidoyer et de Mobilisation des Ressources en faveur de la Lutte contre le Paludisme 2024–2028 en République Démocratique du Congo vise à renforcer l’engagement politique, mobiliser des financements domestiques et internationaux et impliquer tous les secteurs (publ...ic, privé, société civile) pour réduire la mortalité liée au paludisme de 70 % et l’incidence de 50 % d’ici 2028.
Le document propose des actions concrètes : plaidoyer auprès des décideurs pour des budgets accrus, exonération des intrants antipaludiques, introduction du vaccin R21/Matrix-M, création de partenariats public-privé, implication des leaders communautaires et campagnes de sensibilisation via les médias. Il s’aligne sur la stratégie mondiale de l’OMS et promeut une approche multisectorielle, coordonnée par le Programme National de Lutte contre le Paludisme avec l’appui de partenaires comme l’USAID et Breakthrough ACTION.
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This guidance covers different options for banning or phasing out a pesticide and suggests related risk reduction measures to be taken during the phase-out period. A key focus of this guidance is how to take action to manage, prevent, minimize, and communicate about identified risks during the imple...mentation of a phase-out strategy. It contains a description of legal aspects to consider when phasing out a product and illustrates how a risk communication plan can be structured and implemented. How different stakeholders may be involved when a pesticide is going to be phased out is also described.
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Despite being a preventable and curable infectious disease, tuberculosis (TB) has continued to elude global controll efforts. In 2023, 8.2 milion people with TB were diagnosed and notified to the WHO, the hightest number ever reported since WHO began tracking.