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Topics in Antiviral Medicine, March 4, 2025
2025 is the first year of this century where child deaths will increase. But we can stop this reversal before it becomes a trend, even in a time of tight budgets. With proven solutions and next-generation innovations that do more with less, we can save millions of children's lives, protect the pro ... more
Addressing the threat of antimalarial drug resistance. This year’s report spotlights the growing threat of antimalarial drug resistance. Partial resistance to artemisinin derivatives – the backbone of malaria treatments after failures of chloroquine and sulfadoxine-pyrimethamine​ – has now b ... more
Technology and digital tools are transforming everyday life, opening new opportunities for women and girls—but they are also being weaponized to harass, threaten, and silence them online. Technology-facilitated violence against women and girls (TF VAWG) is now a defining challenge for gender equal ... more
Why this document? The Waste Value Chain Analysis (WVCA) has been designed to help organizations understand local waste value chains, with the aim: To identify gaps and opportunities for improvement of local waste value chains (e.g. where shredding, baling can make recovery profitable) and much more ... more
Module 2.1
The handbook includes evidence-based mental health interventions, drawn from the WHO mhGAP guidelines for mental, neurological, and substance use disorders (3), particularly those listed in the UHC Compendium. Evidencebased interventions to reduce population health-related stigma and discriminatio ... more
This document provides an overview of the updated World Health Organization recommendations for HIV clinical management, which focus on optimizing antiretroviral therapy, preventing vertical transmission, and enhancing tuberculosis prevention among individuals with HIV. These updates are intended to ... more
Esc Anna Nery 2024;28:e20240093
The guidelines present and discuss new recommendations and consolidate a range of recommendations and guidance from current WHO guidelines which are summarised here in this policy brief.
These guidelines focus on the collection and use of person-centred data across the HIV cascade – from prevention, testing and treatment to longer-term health care – building upon 2017 and 2020 strategic information guidelines. The updated guidelines present a standard minimum dataset, priority i ... more
Operational requirements for implementing WHO recommendations in digital systems. 2nd edition. To ensure that countries can effectively benefit from digital health investments, “digital adaptation kits” (DAKs) are designed to facilitate the accurate reflection of WHO’s clinical, public health ... more

Principles of HIV drug resistance testing and interpretation

Levin, L. Dept. of Health, South Africa; PEPFAR (2023) C1
Presentation
The impact of intersecting issues and key continental priorities
Continuum of HIV services refers to a comprehensive package of HIV prevention, diagnostic, treatment, care and support services provided for people at risk of infection or living with HIV and their families. This revised edition of the guidelines for use of ARV and opportunistic infection (OI) dru ... more
Regional data extracted from the 2023 Global AIDS Update
By 2030, without accelerated scale-up of prevention and treatment coverage there may be an estimated 320 000 new HIV infections and 7.6 million people living with HIV
This issue brief provides information about TB and HIV clinical trials and research programs impacted by U.S. government funding disruptions, and proposes urgent actions that donor agencies, governments, and philanthropies can take to preserve scientific advances underway and prevent the collapse ... more
These 2025 guidelines respond to the need for better approaches to identify advanced HIV disease, improve the poor outcomes of people living with HIV being discharged from hospital and provide updated guidance for treatment for Kaposi’s sarcoma through evidence-informed recommendations. The public ... more
A toolkit for health facilities. This toolkit highlights successful differentiated-care approaches implemented in a number of settings and countries in sub-Saharan Africa. The toolkit will be further updated as more experience is gained with these and similar approaches