Following review of the latest evidence, WHO recommends that TB-LAMP can be used as a replacement for microscopy for the diagnosis of pulmonary TB in adults with signs and symptoms of TB. It can also be considered as a follow-on test to microscopy in adults with signs and symptoms of pulmonary TB, e...specially when further testing of sputum smear-negative specimens is necessary.
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PQDx 0006-005-00 WHO
PQDx PR
February/2016, version 2.0
The technical note from the Global Task Force on Cholera Control (GTFCC) examines the risks and benefits of vaccinating pregnant women with WHO-prequalified oral cholera vaccines (OCVs) during mass vaccination campaigns. It highlights that three WHO-approved vaccines (Dukoral®, Shanchol™, and Euv...ichol®) offer sustained protection and a strong safety profile.
While these vaccines are not explicitly contraindicated for pregnant women, there is limited clinical data on their use during pregnancy. However, studies indicate that pregnant women with cholera face higher risks of fetal loss, stillbirth, and complications, especially if they experience severe dehydration. Some evidence suggests that vaccination can reduce cholera incidence in pregnant women and indirectly protect infants.
Although no controlled trials have focused on pregnant women, retrospective studies in Guinea and Zanzibar showed no significant increase in adverse pregnancy outcomes after OCV administration. The GTFCC concludes that the benefits of vaccination outweigh the risks, particularly in high-risk areas, and recommends including pregnant women in cholera vaccination campaigns while continuing to monitor safety data.
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- The goal of diagnostic testing for Ebola and Marburg virus diseases is to identify cases to provide timely and appropriate care and to stop disease transmission.
- All individuals meeting the case definition for Ebola or Marburg virus diseases should be tested.
- The recommended sample type ...for testing for orthoebolaviruses and orthomarburgviruses is whole blood or plasma for living patients, and oral swab for deceased individuals.
- Laboratory confirmation of Orthoebolavirus and Orthomarburgvirus infections and further species identification should be done using nucleic acid amplification testing (NAAT).
- If a suspected case tests negative (living patient) and the blood was drawn less than 72 hours after symptom onset, a second test should be performed with blood drawn more than 72 hours after symptom onset.
- All manipulations in laboratory settings of samples originating from suspected, probable or confirmed cases of Ebola and Marburg virus diseases should be conducted with appropriate biosafety measures according to a risk-based approach.
- Whole or partial genome sequencing can be used to characterize viruses and complement epidemiologic investigations.
- Member States are strongly encouraged to share genetic sequence data (GSD) in publicly accessible databases.
- Member States are required to immediately notify the World Health Organization (WHO) under the International Health Regulations (IHR) 2005 of positive laboratory results.
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Рекомендации ВОЗ по оказанию дородовой помощи для формирования положительного опыта беременности
Guía de prácticas esenciales. Segunda edición
A Manual for mid-level rehabilitation workers.
This manual is to support the work of mid-level rehabilitation workers on their work with children or adults with spinal cord injury and their families. It refers to the physical effects of this type of injury, the different levels of injury and the ba...sic care of a person following a spinal cord injury. Available in Chinese and Mongolian, too
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Regional Tuberculosis Program, Pan American Health Organization (PAHO/WHO)
This course will equip clinicians who frequently prescribe antimicrobials with knowledge and tools to improve their use of these essential medications in daily clinical practice. Through case based examples, the course will highlight how antimicrobial stewardship principles can be applied to common ...clinical scenarios. We will first review foundational clinical knowledge necessary to use antimicrobials wisely. Then, we will illustrate how clinicians can incorporate this knowledge into the management of patients with common infections through adherence to the five core competencies of appropriate antimicrobial prescribing. This course will provide a framework for approaching each clinical encounter from the perspective of combating antimicrobial resistance.
The course is available in English, French, Italian, Russiand and Spanish
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This report provides updated information on the status of implementation of the International Code of Marketing of Breast-milk Substitutes (BMS) and subsequent relevant World Health Assembly (WHA) resolutions (collectively referred to as “the Code”) in countries. It presents the legal status of ...the Code, including the extent to which the provisions of the Code have been incorporated in national legal measures. The report examines further the processes countries use to monitor and enforce compliance with Code laws. The report also provides case-studies from a few countries on their legislative processes, highlighting examples of interference from manufacturers and distributors of breast-milk substitutes in efforts to weaken and delay Code implementation.
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