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Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infecti...ons are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

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Cardiovascular diseases (CVDs)

World Health Organization WHO (2021) C_WHO

Key facts - Cardiovascular diseases (CVDs) are the leading cause of death globally. - An estimated 17.9 million people died from CVDs in 2019, representing 32% of all global deaths. Of these deaths, 85% were due to heart attack and stroke. - Over three quarters of CVD deaths take place in low- an... more

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Covid-19 and violence against older people

WHO (2020) C_WHO

Brochure on 'increase in the risk of violence against older people' and what can be done to adress it.

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National Strategic Plan Public Private Mix in Tuberculosis (2016-2020)

National TB Control Programme (NTP), DGHS, MoHFW (2016) C1

This 2016-2020 public-private mix strategic plan (PPM SP) is a 4-year framework designed to guide the National TB Control Programme (NTP) and its partners to implement PPM in Bangladesh. It provides goals, strategies and interventions for expanding and scaling up current PPM models and outlines appr... more

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Self-reported disability in rural Malawi: prevalence, incidence, and relationship to chronic conditions

Prynn, J.E.; Dube, A.; Mwaiyeghele, E. et al. Wellcome Open Research (2022) CC

Background: Disability is a complex concept involving physical impairment, activity limitation, and participation restriction. The Washington Group developed a set of questions on six functional domains (seeing, hearing, walking, remembering, self-care, and communicating) to allow collection of co... more

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Cameroun : de la réorientation des soins de santé primaires au plan national de développement sanitaire

Okalla R.; A. Le Vigouroux (2001) C1

Bulletin de l'APAD, 21 | 2001

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Zwischen Trauma und Hoffnung

Jiyan Foundation for Human Rights (2016) C1

Mit dieser Broschüre möchten wir die Erfahrungen unserer KlientInnen einem breiteren Publikum zugänglich machen. Allzu häufig wird Unrecht im Irak mit dem Mantel des Schweigens bedeckt, und bis heute halten Menschenrechtsverletzungen in diesem Land an. Umso wichtiger ist es, diese sichtbar und ... more

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Free Online Health & Medicine Courses

class central (2021) CC

Best online courses in Health & Medicine from University of Tasmania, Wageningen University, University of Cape Town, Yale University and other top universities around the world.

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Indikator Kesehatan Indonesia 2005-2009

Pusat Data dan Surveilans Epidemiologi Kementerian Kesehatan Republik Indonesia (2010) C1

Booklet of Health Indicators in Indonesia 2005-2009

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Emergency medical care

WHOSEARO (2013) C_WHO

Training Manual for Doctors. Cardiac deaths are highest cause of death in Bangladesh. Trauma, burn, poisoning and snake bite are commonly encountered in the emergency room of a hospital. Road traffic injuries, fire, collapse of a building etc. are sometimes bad to rush of a large number of patients... more

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Guidelines for the Structure of Public Health Entomology Laboratories

Pan American Health Organization (PAHO) (2019) C_WHO

This document provides countries with recommendations for structuring a public health entomology laboratory network. The document will help countries to identify their areas of need and determine how the entomology network can be strengthened, especially in the context of a decentralized health syst... more

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Training Manual: Climate and Health

International Federation of Medical Students’ Associations (IFMSA) (2016) C1

The project was developed by the International Federation of Medical Students’ Associations (IFMSA), in line with the Federation’s statement “a world in which students are equipped with knowledge, skills and value to take on health leadership roles locally and globally so to... more

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Football Combating Malaria (FCM) - Guide de formation

Speak up Africa (2018) C2

Guide dédié à la formation des agents de changement sur la sensibilisation à la lutte contre le paludisme en milieu communautaire. Ce guide se concentre sur le processus impliqué dans l’adoption de nouvelles attitudes et développe une stratégie de conscientisation et de mobilisation social... more

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Hand hygiene for all

UNICEF, WHO (2020) C_WHO

Three billion people – 40 per cent of the world’s population – do not have a place in their homes to wash their hands with water and soap. Three quarters of those who lack access to water and soap live in the world’s poorest countries and are amongst the most vulnerable: children and familie... more

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Keep Safe - Keep Serving. Standard Safety Measures for Health Worker
recommended

World Health Organization; Christian Health Association Liberia (2014)

Reproduced by CHAL (Chrisitan Health Association Liberia) 3 October 2014

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Where there is no psychiatrist : a mental health care manual

Patel, Vikram Royal College of Psychiatrists (2003) C2

This book is a practical manual of mental health care for community health workers, primary care nurses, social workers and primary care doctors, particularly in developing countries.Helpful features include: over 50 illustrations and case studies, jargon-free explanations and descriptions, flow-cha... more

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UNHCR’s mental health and psychosocial support

Meyer, S. UNHCR (2013) C2

A broad range of UNHCR’s key priorities overlap with MHPSS issues – for example, child protection and sexual and gender-based violence [SGBV] prevention and response. Despite all these existent synergies, UNHCR’s current policies and guidelines do not sufficiently link with MHPSS principles.... more

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International Maternal & Child Health Care - A practical manual for hospitals worldwide

Maternal & Childhealth Advocacy International (MCAI) , Advanced Life Support Group (ALSG) Radcliffe (2015) C2

The purpose of adding the books to the website of MCAI for download, is to make this life-saving, up-to-date information available to all who need it. Fill in a short registration field and you can download the pdf-files. If you work in a hospital in a low income country - providing free care - y... more

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HIV and young men who have sex with men

World Health Organization; UNFPA; UNAIDS; etc al. (2015) C_WHO

Technical Brief Damon Barrett, Gonçalo Figueiredo Augusto, Martiani Oktavia, Jeanette Olsson, Mira Schneiders and Kate Welch provided background papers and literature reviews which informed this technical series.

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Do no harm: Maternal, newborn and infant care during COVID-19

UN Children's Fund (2021) C_UNICEF

This brief summarizes current evidence and guidance for maintaining safe and effective care across the spectrum of maternal, newborn and infant care while protecting mother and child and health care providers during COVID-19. Furthermore, implications of the principle of “do no harm” are reviewe... more

Keep Safe - Keep Serving. Standard Safety Measures for Health Worker recommended

Keep Safe - Keep Serving. Standard Safety Measures for Health Worker
recommended