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WHO guideline on balanced national controlled medicines policies to ensure medical access and safety
Access to medicines is essential for attainment of universal health coverage, which is central to achievement of the health-related Sustainable Development Goals. Controlled medicines include those such as opioids, benzodiazepines, barbiturates, amphetamines and others with identified or emergent cl
...
inical indications. WHO recognizes that these medicines are necessary for pre- and post-operative care, for sedation, for the management of both acute and chronic pain, for palliative care, as anticonvulsants (anti-epileptics), for the management of anxiety disorders and for the management of substance use disorders, including as opioid agonist therapy (OAT).
more
20 YEARS OF STRATEGIC HIV AND PUBLIC HEALTH DATA . beThe completion of the 6th South African National HIV Prevalence, Incidence and Behaviour Survey (SABSSM) report, coincides with the celebration of 30 years of democracy in South Africa; and marks 20 years of conducting nationally representative ho
...
usehold-based surveys by the Human Sciences Research Council (HSRC), its collaborators and donors. Since its inception in 2002, the SABSSM series has emerged as one of the HSRC’s leading scientific contributions to the country’s HIV and AIDS response (1), providing essential data to monitor the HIV epidemic, the impact of the HIV program in South Africa, and to inform strategies for epidemic control in the National Strategic Plan for HIV, TB and STIs (NSP), now in its fifth edition. Using scientific evidence from SABSSM and other key sources, the NSP guides the country’s response, under the leadership of the South African AIDS Council (SANAC) and the National Department of Health (NDoH), with focus on equitable access to biomedical interventions, addressing the structural and social behavioural drivers of the epidemic, and targeting populations disproportionately affected by HIV; such as, black Africans, key populations and adolescent girls and young women (AGYW) aged 15–24 years (2).
more
PHSM are vital in reducing the risk and scale of infectious disease transmission and lowering hospitalization and deaths. Examples include contact tracing, quarantine and isolation, mask use, ventilation, school or workplace measures, mobility restrictions and travel requirements.
While these mea
...
sures are essential, decision-making on PHSM becomes particularly complex during rapidly evolving health emergencies, with incomplete information and under significant public and political pressure, especially when the pathogen is novel or poorly understood. In such contexts, guidance needs to be agile and responsive, developed and adapted based on emerging evidence and shifting epidemiological patterns. Decision-makers are frequently confronted with difficult trade-offs, having to balance measures that are:
─ effective but socially disruptive;
─ cost-effective but logistically burdensome;
─ beneficial for public health but economically disruptive; or
─ practical but inequitable or unethical
more
This brief report summarizes recent information on HIV drug resistance (HIVDR) in the era of integrase-strand transfer inhibitors (INSTI) for HIV prevention and treatment.
Adolescents and young adults aged 10-24 remain underserved in the global response against HIV. Combination prevention, treatment and care programmes use a mix of evidence-based interventions to meet the current HIV prevention needs of adolescents and young adults. However, there needs to be a focus
...
on priority interventions that are evidence-based, practical, contextual and sustainable. This document highlights interventions and recommendations that have passed through the evidence-based lens of the WHO.
more
Strengthening global health security to protect the world against future epidemics and pandemics requires well-tested and decentralized capacities for the local detection and rapid containment of outbreaks of infectious disease. For such capacities to translate into effective response actions, ind
...
ividuals and teams must be well connected and coordinated, despite differences in the size, geography, technical focus or constituency of their parent institution.
more
The primary audience for this guideline includes policy-makers or service providers who are responsible for developing national and local health-care protocols and policies related to care during pregnancy, childbirth and the postnatal period, and those directly providing care to women during pregna
...
ncy, including obstetricians, midwives, endocrinologists, nurses, general practitioners, dietitians and diabetes educators, and managers of maternal and child health programmes, in all settings.
more
Abrupt reductions in international HIV assistance in 2025 have deepened existing funding shortfalls. The OECD estimates that external health assistance is projected to drop by 30–40% in 2025 compared with 2023, causing immediate and even more severe disruption to health services in low- and middle
...
-income countries.
more
Building true health security in a global age. Findings and recommendations of the Global Council. In landmark findings based on two years of research and convenings around the world, the new report shows that high levels of inequality are linked to outbreaks becoming pandemics and that inequality i
...
s undermining national and global responses, making pandemics more disruptive, deadly, and longer in duration. The report also shows that pandemics increase inequality, fuelling a cycle that research shows is visible not just for COVID-19, but also for AIDS, Ebola, Influenza, Mpox and beyond.
more
These guidelines, produced in 2022 by the Uganda Ministry of Health, provide guidance on the diagnosis of HIV, the care of people living with HIV, and the use of antiretroviral drugs for treating and preventing HIV infection, including injectable cabotegravir and the dapivirine vaginal ring.
Module 2.1
Technical Brief
Background Note: Briefing to the Executive Board, First Regular Session 2025
Progress on the sustainable development goals.
EDCTP Stakeholder meeting
Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV
recommended
Panel on Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV
ClinicalInfo.gov
(2025)
C_CDC
The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and
Adolescents With HIV document is published in an electronic format and updated as relevant changes
in prevention and treatment recommendations occur.
This issue brief provides information about TB and HIV clinical trials and research programs
impacted by U.S. government funding disruptions, and proposes urgent actions that
donor agencies, governments, and philanthropies can take to preserve scientific advances
underway and prevent the collapse
...
of TB and HIV medical research in South Africa
more
The adopted pillars for the AEVT Plan are a) early testing among children exposed to HIV, syphilis and HBV; b) closing the treatment gap among PBFW and children exposed to HIV, syphilis and HBV; c) prevention of new HIV, syphilis and HBV infections among PBFW; and d) breaking down barriers to access
...
to integrated services. Based on these pillars, the AEVT plan guides galvanizing political advocacy for the last mile toward the elimination of vertical transmission of HIV, syphilis and HBV in Africa by 2030
more
Pathogens 2022, 11, 33. https://doi.org/10.3390/pathogens11010033
A Training Curriculum
