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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Usage des antimicrobiens dans: les établissements de soins de longue durée

European Centers for Disease Control and Prevention ECDC (2018) C2

affiche - disponible en différentes langues

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Runny Nose from a Cold & Antibiotics

CDC Centers for Disease Control and Prevention (2019) C_CDC

Q & A Guide for Parents - Factsheet

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Cadre continental sur le renforcement des systèmes de surveillance de la mortalité en Afrique

Africa Center for Disease Control and Prevention (2023) CC

L'importance de systèmes de surveillance de la mortalité robustes ne peut être surestimée à une époque marquée par des défis sanitaires mondiaux croissants, où les menaces sanitaires pèsent lourd et la dynamique des populations continue d'évoluer. Des données précises et opportunes sur ...la mortalité sont essentielles pour identifier les tendances et détecter les menaces émergentes pour la santé, évaluer l'impact des interventions et orienter les décisions politiques fondées sur des données probantes. Ce cadre décrit une approche holistique pour renforcer les systèmes de surveillance de routine de la mortalité, en tenant compte des facteurs contextuels uniques et des défis auxquels sont confrontés les pays africains. Il souligne l'importance d'établir des mécanismes de collecte de données efficaces, d'améliorer la qualité et l'exhaustivité des données et de promouvoir le partage des données et la collaboration entre les parties prenantes. De plus, le cadre reconnaît le rôle central de la technologie dans l'intégration des données provenant de sources de données fragmentées sur la mortalité. Il met en évidence le potentiel des méthodes innovantes de capture de données, des analyses avancées et des systèmes de notification en temps réel pour améliorer la précision, l'efficacité et l'actualité des données sur la mortalité. Le cadre continental de surveillance de la mortalité s'aligne sur la mission et l'objectif stratégique d'Africa CDC en servant d'élément fondamental dans le renforcement des systèmes de santé publique, l'amélioration des capacités et des capacités de surveillance des maladies, l'élaboration de politiques et d'interventions fondées sur des données probantes et la promotion de la collaboration et de la coordination entre les pays africains pour relever les défis sanitaires et améliorer les résultats sanitaires sur le continent. La mise en œuvre réussie de ce cadre nécessite un engagement collectif et des efforts concertés de la part des gouvernements, des établissements de santé et de la communauté internationale. Nous espérons que ce document servira de catalyseur pour un changement transformateur, permettant aux pays de mettre en place des systèmes de surveillance de la mortalité résilients qui protègent la santé publique, sauvent des vies et contribuent à la prise de décision fondée sur des données probantes. more

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Uso de antimicrobianos en:centros sociosanitarios de larga duración

European Centers for Disease Control and Prevention ECDC (2018) C2

póster - disponible en diferentes idiomas

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Patient Dialogue - A practical illustration of the elicit-provide-elicit method

European Centers for Disease Control and Prevention ECDC (2019) C2

The method, entitled “elicit-provide-elicit”, is a patient centred method which is adaptable to a range of clinical situations. Recent clinical trials show that the introduction of advanced communication skills based on this method in general practice allows primary care physicians to prescribe... more

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How does antimicrobial resistance spread? - Animation

European Centers for Disease Control and Prevention ECDC (2017) C2

How does antibiotic resistance spread? Antibiotic resistance is the ability of bacteria to combat the action of one or more antibiotics. Humans and animals do not become resistant to antibiotic treatments, but bacteria carried by humans and animals can.

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Un compromiso hacia nuestros pacientes sobre los antibióticos

CDC Centers for Disease Control and Prevention (2019) C_CDC

Los antibióticos tratan solamente las infecciones causadas por bacterias. Como todos los medicamentos, los antibióticos pueden ser dañinos y deben usarse solo cuando sea necesario.

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Amélioration de l’utilisation des antibiotiques

CDC Centers for Disease Control and Prevention (2019) C_CDC

Ai-je réellement besoin d’antibiotiques? -Fiche d'information pour les patients

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Les antibiotiques ne sont pas toujours la solution

CDC Centers for Disease Control and Prevention (2019) C_CDC

Fiche d'information pour les patients

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Inpatient Fact sheet

CDC Centers for Disease Control and Prevention (2019) C_CDC

Your healthcare team has decided you or your loved one has an infection that requires antibiotics, or needs antibiotics to prevent an infection in certain circumstances, such as before surgery - Fact Sheet for Patients

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Antimicrobial use in:Long-term care facilities

European Centers for Disease Control and Prevention ECDC (2018) C2

Poster - Available in Different languages

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TB 101 para trabajadores de la salud

CDC Centers for Disease Control and Prevention (2020) CC

Es un curso en línea diseñado para educar a los trabajadores de la salud en conceptos básicos relacionados con la prevención y el control de la tuberculosis (TB) en los Estados Unidos. Este curso está dirigido a una audiencia que incluye al personal del programa de la TB recién contratado y a ... more

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Boîte à outils pour s’investir dans les médias sociaux en vue de promouvoir l'utilisation prudente des antibiotiques

European Centers for Disease Control and Prevention ECDC (2012) C_CDC

Ce document d'orientation est basé sur une recherche sur les activités des médias sociaux liées à l'utilisation des antibiotiques au niveau de l'UE, ainsi que sur une enquête sur les activités des médias sociaux des organisations partenaires de l'EAAD, principalement des organisations de pat... more

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Infographic: COVID-19 contact tracing

European Centers for Disease Control and Prevention ECDC (2020) C_CDC

Contact tracing is a core public health response to COVID-19.Other measures include active case finding or physical distancing. In order to trace a contact, we first need to define what a ‘contact’ is.

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Position Statement on transmission of SARS-CoV-2 by pre-asymptomatic and asymptomatic individuals

Africa CDC Centers for Disease Control and Prevention (2020) C1

Over the past weeks, there has been wide media attention on the risk of transmission of the novel coronavirus [severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)] by asymptomatic individuals. This situation has also been extensively discussed on various platforms globally. The purpose of t... more

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Herramientas para participar en las redes sociales y promover el uso prudente de los antibióticos

European Centers for Disease Control and Prevention ECDC (2012) C_CDC

Este documento de orientación se basa en la investigación de la actividad de los medios sociales relacionados con el uso de antibióticos a nivel de la UE, así como en una encuesta sobre las actividades de los medios sociales de las organizaciones asociadas a la EAAD, en su mayoría organizacione... more

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Guidance on easing lockdown

Africa CDC Centers for Disease Control and Prevention (2020) CC

In response to the first cases of coronavirus disease 2019 (COVID-19) reported on the continent, many African Union Member States implemented large-scale public health and social measures (PHSM) rapidly. These measures were aimed at reducing transmission and the number of new cases being reported, p... more

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Los antibióticos no son siempre la solución

CDC Centers for Disease Control and Prevention (2019) C_CDC

Hoja informativa para los pacientes

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Africa’s Health Financing in a New Era

Africa Centres for Disease Control and Prevention (Africa CDC) (2025) CC

Africa’s health sector is facing an unprecedented financing crisis, driven by a sharp decline of 70% in Official Development Assistance (ODA) from 2021 to 2025 and deep-rooted structural vulnerabilities. This collapse is placing immense pressure on Africa’s already fragile health systems as ODA ...is seen as the backbone of critical health programs: pandemic preparedness, maternal and child health services, disease control programs are all at risk, threatening Sustainable Development Goal 3 and Universal Health Coverage. Compounding this is Africa’s spiraling debt, with countries expected to service USD 81 billion by 2025—surpassing anticipated external financing inflows—further eroding fiscal space for health investments. Level of domestic resources is low. TThe Abuja Declaration of 2001, a pivotal commitment made by African Union (AU) member states, aimed to reverse this trend by pledging to allocate at least 15% of national budgets to the health sector. However, more than two decades later, only three countries—Rwanda, Botswana, and Cabo Verde—have consistently met or exceeded this target (WHO, 2023). In contrast, over 30 AU member states remain well below the 10% benchmark, with some allocating as little as 5–7% of their national budgets to health. In addition, only 16 (29%) of African countries currently have updated versions of National Health Development Plan (NHDP) supported by a National Health Financing Plan (NHFP). These two documents play a critical role in driving internal resource mobilisation. At the same time, public health emergencies are surging, rising 41%—from 152 in 2022 to 213 in 2024—exposing severe under-resourcing of health infrastructure and workforce. Recurring outbreaks (Mpox, Ebola, cholera, measles, Marburg…) alongside effects of climate change and humanitarian crises in Eastern DRC, the Sahel, and Sudan, are overwhelming systems stretched by chronic underfunding. The situation is worsened by Africa’s heavy dependency with over 90% of vaccines, medicines, and diagnostics being externally sourced—leaving countries vulnerable to global supply chain shocks. Health worker shortages persist, with only 2.3 professionals per 1,000 people (below the WHO’s recommended 4.45), and fewer than 30% of systems are digitized, undermining disease surveillance and early warning. Without decisive action, Africa CDC projects the continent could reverse two decades of health progress, face 2 to 4 million additional preventable deaths annually, and a heightened risk of a pandemic emerging from within. Furthermore, 39 million more Africans could be pushed into poverty by 2030 due to intertwined health and economic shocks. This is not just a sectoral crisis—it is an existential threat to Africa’s political, social, and economic resilience, and global stability. In response, African leaders, under Africa CDC’s stewardship, are advancing a comprehensive three-pillar strategy centered on domestic resource mobilization, innovative financing, and blended finance. more