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2
Fexinidazole and Human African Trypanosomiasis: good news for this important neglected tropical disease
Bayão T.S., Cupertino M.C., Gomes A.P. et al
Journal of the Brazilian Society of Tropical Medicine
(2019)
C2
Human African trypanosomiasis (HAT), or sleeping sickness, is an endemic disease in 36 sub-Saharan African countries, typically occurring in underdeveloped areas, where
health systems face significant difficulties of diverse natures.
Prevention of stroke and transient ischemic attack includes both conventional approaches to vascular risk factor management (blood pressure lowering, cholesterol reduction with statins, smoking cessation and antiplatelet therapy)
and more specific interventions, such as carotid revascularization or
...
anticoagulation for atrial fibrillation. The objective of this review is to discuss effective interventions for optimal primary and secondary stroke prevention.
more
The article is a scoping review that explores the challenges in diagnosing asthma in children in three sub-Saharan African countries: Nigeria, South Africa, and Uganda. It identifies key barriers, such as a lack of community awareness, inadequate healthcare access, limited diagnostic tools like spir
...
ometry, and insufficient knowledge among healthcare workers. The review also highlights the stigma associated with asthma and the absence of relevant diagnostic guidelines. Solutions proposed include community education, development and adherence to diagnostic guidelines, and strengthening healthcare systems. The study aims to inform policymakers and healthcare providers to improve asthma diagnosis and care for children in these regions.
more
The objectives of the research presented in this report were to identify case studies of community-led HIV-related health and social inclusion service delivery organizations in eastern and southern Africa; describe the typologies of the services pro
...
vided; and identify evidence of their service delivery and contribution beyond HIV, including advancing universal health coverage.
more
This manual is part of a series of guides devised by the Oxfam Public Health Engineering Team to help provide a reliable water supply for populations affected by conflict or natural disaster. Storage tanks are required for collection of water from s
...
prings or water produced from continuous flow water treatment systems, e.g. from upflow clarifiers or slow sand filters. There should be sufficient storage volume to store all water produced overnight, as this is unlikely to be collected by users during the night. Storage tanks also have secondary functions such as ensuring a constant water supply to treatment processes, providing a level of treatment by settlement of larger suspended solids and maintaining pressure in distribution systems
more
This manual is part of a series of guides devised by the Oxfam Public Health Engineering Team to help provide a reliable water supply for populations affected by conflict or natural disaster. The equipment is designed to be used with any or all of t
...
he following Oxfam water equipment: Water Pumping equipment, Water Storage equipment, Water Filtration equipment, Water Distribution equipment, Hand-dug Well equipment, and Water Testing Kit. All are designed using available, easily transported equipment which is simple, rapidly assembled, and fully self-contained, to provide an adequate, safe water supply at moderate cost. The principles used in these packages may often be useful in long-term development projects.
more
Emergency Capacitiy Building Project agencies, led by CARE, have developed the Shelter Accountability Resources for project managers and decision-makers in humanitarian shelter programs.
As a guide it is also intended to be useful for Shelter Clu
...
ster coordinators, and other staff who would like to monitor the accountability of particular projects and programs. The tools and examples included here should help humanitarians to plan, implement and monitor shelter projects and programs in a way that is accountable to disaster-affected populations.
more
To generate and manage resources towards this goal, the UN Secretary-General in collaboration with UN Agencies, Funds and Programmes (UN AFP) has launched the UN Zika Response Multi-Partner Trust Fund (Zika Response MPTF). The aim of this inter-agency pooled funding mechanism is to rapidly resource
...
the UN system responses to Zika virus, in accordance with the overview of needs and requirements and the Zika Response Framework.
more
WASH and the Neglected Tropical Diseases
Ogden, S., Gallo, K., Davis, S., et al
Sightsavers, Department for International Development, The International Trachoma Initiative , et al.
(2013)
C2
A MANUAL FOR WASH IMPLEMENTERS, BOTSWANA
Sightsavers | Department for International Development | The International Trachoma Initiative | Children Without Worms | WaterAid | WASH Advocates | Center for Global Safe Water, Emory University | CARE USA
...
more
This study aimed to understand the patterns of HIV drug resistance in pregnant women in Mozambique. This might help in tailoring optimal regimens for prevention of mother to child transmission of HIV (pMTCT) and antenatal care.
This document was prepared in response to a need to review and potentially update the current recommendations for the antibiotic treatment of both inpatient and outpatient management of severe acute malnutrition (SAM). The current recommendations (Table 1) are based on guidelines published in 2013 i
...
n the WHO Pocketbook for Hospital Care for Children, and the 2013 update on SAM (outpatient management). The global threat of increasing antimicrobial resistance and new data on efficacy and safety profiles requires a re-review of the current evidence to ensure recommendations are the most appropriate. The evidence base for the use of antibiotics in children presenting with uncomplicated SAM has been recently enlarged.
more
This study aims to analyze national and international stakeholders and their initiatives in Early Warning Systems in Myanmar, to identify priority gaps that need to be addressed by all stakeholders. It is presented as a first step towards supporting GoUM in information-gathering under the Myanmar Ac
...
tion Plan for Disaster Risk Reduction (MAPDRR), in particular under Components (2) Risk Assessment, (3) Multi-hazard Early Warning System and (4) Preparedness at all levels, and especially in implementing Sub-Component (3.4) Enhanced Flood Monitoring and Forecasting Capacities at Township Levels.
more
more
Prepared as an outcome of ICMR Subcommittee on Gastric Cancer | This consensus document on Management of Gallbladder cancers summarizes the modalities of treatment including the site-specific anti-cancer therapies, supportive and palliative care and
...
molecular markers and research questions. It also interweaves clinical, biochemical and epidemiological studies.
more
Prepared as an outcome of ICMR Subcommittee on Non Hodgkin’s Lymphoma (High Grade) | This consensus document on management of non- hodgkin’s lymphoma – high grade summarizes the modalities of treatment including the site-specific anti-cancer therapies, supportive and palliative
...
care and molecular markers and research questions. It also interweaves clinical, biochemical and epidemiological studies.
more
This 2019 edition of The State of the World’s Children (SOWC) examines the issue of children, food and nutrition, providing a fresh perspective on a rapidly evolving challenge. Despite progress in the past two decades, one third of children under age 5 are malnourished – stunted, wasted or overw
...
eight – while two thirds are at risk of malnutrition and hidden hunger because of the poor quality of their diets. At the center of this challenge is a broken food system that fails to provide children with the diets they need to grow healthy. This report also provides new data and analyses of malnutrition in the 21st century and outlines recommendations to put children’s rights at the heart of food systems.
more
Antibiotic resistance has been recognized as a major global health threat and optimizing prescribing is one of the most effective measures to preserve the effectiveness of antibiotics. The quality of prescribing depends mostly on those pres
...
cribers belonging to clinical medical specialties having direct contact with patients. These doctors, who comprise the majority of antibiotic prescribers,undergo long-term undergraduate and postgraduate training that shapes their professional knowledge and behaviour
J Antimicrob Chemother2019;74: 3611–3618doi:10.1093/jac/dkz375 Advance Access publication 3 September 2019
more
The United Nations Development Programme (UNDP) today released two new data dashboards that highlight the huge disparities in countries’ abilities to cope with and recover from the COVID-19 crisis.
The pandemic is more than a global health emer
...
gency. It is a systemic human development crisis, already affecting the economic and social dimensions of development in unprecedented ways. Policies to reduce vulnerabilities and build capacities to tackle crises, both in the short and long term, are vital if individuals and societies are to better weather and recover from shocks like this.
more
With the spread of the coronavirus (COVID-19) across Myanmar, many children and caregivers are required to stay in quarantine centres, in isolation and in hospitals, and special attention is needed to ensure children’s rights are protected in these settings. Violence, exploitation, abuse and negle
...
ct still occurs despite COVID-19 and continuity of the child protection case management system is essential to protect all children, including the most vulnerable. UNICEF’s Child Protection support focuses on mitigating the secondary impacts of physical distancing measures by ensuring children, parents and caregivers continue to have access to child protection services.
more
The COVID-19 pandemic has impacted the world and consequently increased MHPSS needs across various contexts. While National Societies respond to the rising mental health and psychosocial support needs, they are also adapting to and implementing remo
...
te support, such as telephone hotlines or other online services. Accordingly, many trainings in psychological first aid (PFA) of staff and volunteers have moved to online platforms.
Throughout the pandemic, the PS Centre developed online approaches, guidances, adaptable tools, videos, podcasts, and other materials on MHPSS. This was to ensure easy access to tools and resources that assist National Societies in their training efforts in MHPSS during COVID-19.
more
BACKGROUND: Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to reduce antimicrobial overuse. A systematic evidenc
...
e map can support governments in making evidence-informed decisions about implementing programs to reduce AMR, by identifying, describing, and assessing the full range of evaluated government policy options to reduce antimicrobial use in humans.
METHODS AND FINDINGS: Seven databases were searched from inception to January 28, 2019, (MEDLINE, CINAHL, EMBASE, PAIS Index, Cochrane Central Register of Controlled Trials, Web of Science, and PubMed). We identified studies that (1) clearly described a government policy intervention aimed at reducing human antimicrobial use, and (2) applied a quantitative design to measure the impact. We found 69 unique evaluations of government policy interventions carried out across 4 of the 6 WHO regions. These evaluations included randomized controlled trials (n = 4), non-randomized controlled trials (n = 3), controlled before-and-after designs (n = 7), interrupted time series designs (n = 25), uncontrolled before-and-after designs (n = 18), descriptive designs (n = 10), and cohort designs (n = 2). From these we identified 17 unique policy options for governments to reduce the human use of antimicrobials. Many studies evaluated public awareness campaigns (n = 17) and antimicrobial guidelines (n = 13); however, others offered different policy options such as professional regulation, restricted reimbursement, pay for performance, and prescription requirements. Identifying these policies can inform the development of future policies and evaluations in different contexts and health systems. Limitations of our study include the possible omission of unpublished initiatives, and that policies not evaluated with respect to antimicrobial use have not been captured in this review.
CONCLUSIONS: To our knowledge this is the first study to provide policy makers with synthesized evidence on specific government policy interventions addressing AMR. In the future, governments should ensure that AMR policy interventions are evaluated using rigorous study designs and that study results are published.
more
