Strict storage recommendations for insulin are difficult to follow in hot tropical regions and even more challenging in conflict and humanitarian emergency settings, adding an extra burden to the management of people with diabetes. According to pharmacopeia unopened insulin vials must be stored in a... refrigerator (2–8°C), while storage at ambient temperature (25–30°C) is usually permitted for the 4-week usage period during treatment. In the present work we address a critical question towards improving diabetes care in resource poor settings, namely whether insulin is stable and retains biological activity in tropical temperatures during a 4-week treatment period. To answer this question, temperature fluctuations were measured in Dagahaley refugee camp (Northern Kenya) using log tag recorders. Oscillating temperatures between 25 and 37°C were observed. Insulin heat stability was assessed under these specific temperatures which were precisely reproduced in the laboratory. Different commercialized formulations of insulin were quantified weekly by high performance liquid chromatography and the results showed perfect conformity to pharmacopeia guidelines, thus confirming stability over the assessment period (four weeks). Monitoring the 3D-structure of the tested insulin by circular dichroism confirmed that insulin monomer conformation did not undergo significant modifications. The measure of insulin efficiency on insulin receptor (IR) and Akt phosphorylation in hepatic cells indicated that insulin bioactivity of the samples stored at oscillating temperature during the usage period is identical to that of the samples maintained at 2–8°C. Taken together, these results indicate that insulin can be stored at such oscillating ambient temperatures for the usual four–week period of use. This enables the barrier of cold storage during use to be removed, thereby opening up the perspective for easier management of diabetes in humanitarian contexts and resource poor settings.
more
Временные рекомендации25 июня 2021 г.
Данный документ представляет собой обновленное
издание рекомендаций «Принципы помещения в
карантин отдельных лиц в контекст... сдерживания
коронавирусного заболевания (COVID-19)»,
опубликованных 19 марта 2020 г. Действие
рекомендаций, представленных в этой версии документа,
распространяется только на случаи карантина для лиц,
которые контактировали с пациентами, имеющими
подтвержденный или вероятный диагноз COVID-19.
В документе содержатся обновленные рекомендации по
реализации карантинных мер, а также дополнительные
рекомендации в отношении вентиляции, а также ухода
за детьми, находящимися на карантине. В основу
данного обновленного издания положены фактические
данные о контроле за распространением вируса
SARS-CoV-2, являющегося возбудителем заболевания
COVID-19, и научные сведения об этом вирусе.
more
interim guidance, 27 May 2021
All countries should increase their level of preparedness, alert and response to identify, manage and care for new cases of COVID-19. Countries should prepare to respond to different public health scenarios, recognizing that there is no one-size-fits-all approach to ma...naging cases and outbreaks of COVID-19. Each country should assess its risk and rapidly implement the necessary measures at the appropriate scale to reduce both COVID-19 transmission and economic, public and social impacts.
more
La recherche des contacts – associée à un dépistage rigoureux, à l’isolement et à la prise en charge des cas – est une stratégie clé pour interrompre les chaînes de transmission du SRAS-CoV-2 et réduire la mortalité associée à la COVID-19.
Frequenz, Adhärenz und Testqualität sind entscheidende Faktoren für den Erfolg
Epidemiologisches Bulletin17 |29. April 2021 . Im vorliegenden Artikel wird erläutert, wie Antigen-Schnelltests zur Pandemiekontrolle beitragen können. Außerdem werden die Chancen und Herausforderungen einer wiede...rholten Testung zur Reduktion des allgemeinen Transmissionsgeschehens und der zu erwartende Einfluss eines freiwilligen Testangebots auf das allgemeine Infektionsgeschehen diskutiert
more
Orientations provisoires, 1er février 2021
La recherche des contacts – associée à un dépistage rigoureux, à l’isolement et à la prise en charge des cas – est une stratégie clé pour interrompre les chaînes de transmission du SRAS-CoV-2 et réduire la mortalité associée... à la COVID-19.
more
A new story book that aims to help children understand and come to terms with COVID-19 has been produced
With the help of a fantasy creature, Ario, “My Hero is You, How kids can fight COVID-19!” explains how children can protect themselves, their families and friends from coronavirus and how to... manage difficult emotions when confronted with a new and rapidly changing reality.
Available in more languages
The book – aimed primarily at children aged 6-11 years old – is a project of the Inter-Agency Standing Committee Reference Group on Mental Health and Psychosocial Support in Emergency Settings, a unique collaboration of United Nations agencies, national and international nongovernmental organizations and international agencies providing mental health and psychosocial support in emergency settings.
Available in different languages
more
Haiti is one of the worst food crises in the world with 46 percent of the population projected to be in high acute food security, mainly due to reduced agricultural production caused by a long period of drought, storms and increased prices of basic foodstuffs, which are compounded by the effects of ...the coronavirus disease 2019 (COVID-19).
more
An interactive tool for partners, manufacturers, and countries to follow the developments of the COVID-19 vaccine market with up-to-date information.
As the designated COVAX procurement coordinator and procurement agent, UNICEF has launched the COVID-19 Vaccine Market Dashboard – an interactive ...tool for countries, partners and industry to follow the developments of the rapidly evolving COVID-19 vaccine market and the efforts of the COVAX Facility to ensure fair and equitable access for every country in the world.
In this first release, the dashboard provides a regularly updated overview of the global research and development pipeline, the projected production capacity, publicly announced bilateral and multilateral supply agreements, as well as reported price points.
more
How far apart should the doses of vaccines be? What if I miss my second dose? Can I get two doses from two different manufacturers? How was safety of vaccines ensured? WHO’s Chief Scientist, Dr Soumya Swaminathan explains in Science in 5.
The Actions for Heroes Guide is developed by the Inter-Agency Standing Committee Reference Group on Mental Health and Psychosocial Support in Emergency Settings (IASC MHPSS RG) to accompany reading the children’s storybook My Hero is You, How kids can fight COVID-19! Available in English, French, ...Spanish and Ukranian
https://interagencystandingcommittee.org/iasc-reference-group-mental-health-and-psychosocial-support-emergency-settings/actions-heroes-guide-heart-heart-chats-children-accompany-reading-my-hero-you-how-kids-can-fight
The storybook My Hero is You explains how children can protect themselves, their families and their friends from the coronavirus and how to manage difficult emotions when confronted with our new and rapidly changing reality. The storybook has been translated into 135+ languages and multimedia adaptations have been made.
more
Actualizadas en el documento titulado «Vigilancia de salud pública en relación con la COVID-19» publicado el 16 de diciembre de 2020
Available in different languages
Animations for social media