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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Preferred Practices for Zithromax® Mass Drug Administration

International Coalition for Trachoma Control ICTC (2013) CC

Countries, partners, and donors are committed to the global elimination of blinding trachoma by 2020. Achieving this public health milestone requires more than funding; it requires health personnel with the right mix of skills, and well supported and managed health systems. Mass drug administratio... more

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Medical PPE production in Africa: Promoting Local Manufacturers to support the COVID-19 Response (Workshop report)

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C1

The global pandemic has highlighted fragility in international supply chains and the dependency of many African countries on imported personal protective equipment (PPE). Market pressures have also increased prices for imported supplies and put additional pressure on areas with limited resources for... more

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Guidance and Toolbox for the Basic Needs Analysis

CaLP DRC Okular Analystis, EU (2017) C1

Version 2 (unedited). The Basic Needs Analysis (BNA) is a multi-sector needs analysis approach that can be applied in both sudden onset and protracted emergencies. The methodology comprises the Guidance (this document) presenting the conceptual BNA framework and related processes, and a Toolbox, whi... more

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Protecting Persons with Diverse Sexual Orientations and Gender Identities

UNHCR (2015) CC

The document at hand presents key findings from a project undertaken globally between July 2014 and May 2015 to assess progress made by UNHCR country and regional operations to effectively protect lesbian, gay, bisexual, and transgender, and intersex (LGBTI) asylum-seekers and refugees. Globally, 10... more

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A Guide to Build Cultural Awareness American Indian and Alaska Native

CultureCard SAMSHA (2009) C1

The purpose of this guide is to provide basic information for Federal disaster responders and other service providers who may be deployed or otherwise assigned to provide or coordinate services in American Indian/Alaska Native (AI/AN) communities. This guide is intended to serve as a general briefi... more

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Youth-Friendly Services - A Manual for Service Providers

EngenderHealth (2002)

All young people, including those with special needs and from the most vulnerable groups, have the right to quality health care services. Unfortunately, this right is not a reality, particularly in the case of sexual and reproductive health services. Many youth in need of sexual and reproductive hea... more

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A household-based community health worker programme for non-communicable disease, malnutrition, tuberculosis, HIV and maternal health: a stepped-wedge cluster randomised controlled trial in Neno Distr

Wroe, E.B.; Nhlema, B.; Dunbar, E.L. et al. BMJ Global Health (2021) CC

Background: Community health worker (CHW) programmes are a valuable component of primary care in resource-poor settings. The evidence supporting their effectiveness generally shows improvements in disease-specific outcomes relative to the absence of a CHW programme. In this study, we evaluated expan... more

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Recomendações para o manejo da asma da Sociedade Brasileira de Pneumologia e Tisiologia – 2020

Menezes Pizzichini, M. M.; de Carvalho-Pinto, R. M.; Delfini Cançado, J. E.; et al. (2020) CC2

The pharmacological management of asthma has changed considerably in recent decades, as it has come to be understood that it is a complex, heterogeneous disease with different phenotypes and endotypes. It is now clear that the goal of asthma treatment should be to achieve and maintain control of the... more

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Healthy Living Toolkit

US Committee for Refugees and Immigrants (2015) CC

The Healthy Living Toolkit is developed to educate refugees, immigrants, resettlement agencies, clinics, community based organizations, and other service providers on refugee health issues. The toolkit presents material in a culturally appropriate manner and is intended to help health care-related p... more

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A new approach to cholera in Haiti: Report by the Secretary-General (A/71/895)

UN General Assembly (2017) C1

On 19 August 2016, the former UN Secretary-General announced a new approach to cholera in Haiti, consisting of two tracks. Track 1 focuses on reducing cholera transmission, improving access to care, and addressing water, sanitation, and health system issues. Track 2 aims to provide material assistan... more

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Epidemic preparedness and response plan for cholera in Syria

World Health Organization (WHO) (2015) C_WHO

The Epidemic Preparedness and Response Plan for Cholera in Syria (November 2015) outlines strategies to prevent, detect, and manage cholera outbreaks in the country, where poor water and sanitation conditions, displacement, and damaged healthcare infrastructure increase the risk of disease spread. T... more

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Orientação para a elaboração de um plano nacional de operacionalização da vacinação contra a COVID-19. Orientação Provisória. 1 de junho de 2021

World Health Organization WHO (2021) C_WHO

Este documento de orientação para elaboração de um plano nacional de operacionalização e vacinação (NDVP) apresenta um esquema que auxilia os países a: desenvolver e atualizar o respectivo NDVP para a introdução de vacinas contra a COVID-19; elaborar estratégias para a operacionalizaçã... more

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Diagnostics, therapeutics, vaccine readiness, and other health products for COVID-19
recommended

World Health Organization WHO (2021) C_WHO

Interim Guidance, 12 July 2021; This tool was developed to assess present and surge capacities for the treatment of COVID-19 in health facilities. It allows health facilities to assess the availability and status of stockout of critical COVID-19 medicines, equipment and supplies on site and to ident... more

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Diagnostic de l’ulcère de Buruli au laboratoire
recommended

Portaels, F. Organisation Mondiale de la Santé (2014) C_WHO

Manuel destiné au personnel de santé. Le présent manuel est un guide spécialisé sur les techniques et les méthodes de laboratoire à utiliser pour le diagnostic de l’ulcère de Buruli, une maladie provoquée par Mycobacterium ulcerans. Destiné aux techniciens et aux scientifi ques de labora... more

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Northeast Nigeria Health Sector - Humanitarian Response Strategy 2025 - 2027 (December 2024)

Government of Nigeria; Health Cluster; World Health Organization WHO (2024) CC

The protracted humanitarian situation in northeastern Nigeria, particularly in Borno, Adamawa, and Yobe (BAY) States, remains a concern due to ongoing insecurity, displacement, food insecurity, disease outbreaks, and climate-related shocks. To address these complex challenges, the health sector has ...developed a comprehensive humanitarian response strategy aligned with the three States Development plans, Durable Solutions for the Population Displacement Plan, and the Humanitarian Need Response Plan for 2025. This strategy aims to reduce morbidity and mortality among crisisaffected populations by ensuring timely, equitable, and effective delivery of lifesaving health services, while strengthen the resilience of health system and enhancing local and national capacities for sustainable health response in protracted emergency. Supported by an in-depth analysis of the ongoing health humanitarian response using the Strengths, Weaknesses, Opportunities, and Threats (SWOT) methodology, the strategy is guided by three key objectives: 1. Provide access to lifesaving interventions and sustain an effective response to the prolonged health emergency. 2. Prevent, mitigate, and prepare for health risks from all hazards and respond to all health emergencies. 3. Advance the primary health care approach and essential health system capacities for universal health coverage. To achieve these objectives, the strategy employs the “Five C” framework which refers to: • Collaborative Surveillance: Enhancing collaborative efforts for effective monitoring. • Community Protection: Implementing community-based protection measures. • Safe and Scalable Care: Ensuring care that is both secure and scalable. • Access to Countermeasures: Facilitating access to necessary countermeasures. • Emergency Coordination: Coordinating emergency responses efficiently. These proactive approaches are designed to be more anticipatory and preemptive rather than reactive, aiming to meet the needs of the crisis-affected population by providing lifesaving interventions, enhancing preventive and anticipatory actions, and ensuring the resilience of the health system. All actions are guided by International Humanitarian Standards and the Humanitarian Principles. The implementation of the health humanitarian response strategy will involve collaboration with local authorities, non-governmental organizations (NGOs), and international organizations. The strategy emphasizes localization and resource mobilization, efficient logistics and supply chain management, mainstreaming protection, and the deployment and training of healthcare workers. Continuous monitoring and periodic evaluation will ensure the effectiveness of the response. Cross-sector collaboration with sectors such as WASH, Nutrition, Education, and Protection will be crucial to enhance the quality and reach of health interventions. Additionally, sustainability and transition approaches will ensure long-term health outcomes and benefits, bridging the gap from humanitarian to development efforts. By adopting this comprehensive approach, the humanitarian response in northeastern Nigeria, particularly in BAY States, can be effectively guided, ultimately reducing the suffering of affected populations. more

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National Guidelines for Integrated Diseases Surveillance and Response Uganda

World Health Organization WHO, Regional Office of Africa; Ministry of Health Uganda (2021) C_WHO

3rd edition. In 2001, Uganda adapted the Integrated Disease Surveillance and Response (IDSR) developed by World Health Organization (WHO) for member states in African region. The Ministry of Health has been implementing the IDSR strategy since then with success across the country. This strategy prov... more

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Regional Plan of Action for Ebola Virus Disease Preparedness in East Africa and Indian Ocean Islands - Emergency Plan of Action (EPoA) operation n° MDR64007

International Federation of Red Cross And Red Crescent Societies (2015)

Situation analysis Description of the disaster An Ebola epidemic that started in March 2014 in Guinea has relentlessly continued to claim lives and to spread to other countries in West Africa. The current Ebola outbreak is the largest in history and the first to affect multiple countries simu... more

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Yo juego y aprendo Material para docentes y educadoras comunitarias. Primera Infancia Indígena

Ministerio de Educación y Ciencias - UNICEF Paraguay (2021) C_UNICEF

I play and learn Material for teachers and community educators. Indigenous Early Childhood

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Yo juego y aprendo. Material para niños y niñas Primera Infancia Indígena

Ministerio de Educación y Ciencias - UNICEF Paraguay (2021) C_UNICEF

I play and learn. Materials for boys and girls Indigenous Early Childhood Este material “YO JUEGO Y APRENDO", material para niños,está dirigido a niños del nivel inicial de tres y cuatro años de edad pertenecientes a pueblos indígenas, se enmarca en los principios y fundamentos del Marco C... more

Diagnostics, therapeutics, vaccine readiness, and other health products for COVID-19 recommended

Diagnostic de l’ulcère de Buruli au laboratoire recommended

Diagnostics, therapeutics, vaccine readiness, and other health products for COVID-19
recommended

Diagnostic de l’ulcère de Buruli au laboratoire
recommended