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The practical guidance in the operational handbook aims to inform the development or revision of national policies and related implementation guidance on the management of TB in children and adolescents under programmatic circumstances and at different levels of the health system. The operational ha... more
N Engl J Med 2022; 386:911-922, DOI: 10.1056/NEJMoa2104535 Four months of antituberculosis treatment was noninferior to 6 months of treatment in children with drug-susceptible, nonsevere, smear-negative tuberculosis (SHINE Study)

Shorter treatment for children with minimal TB

SHINE Medical Research Council Clinical Trials Unit (MRC CTU) at UCL (2022) CC
The results of the SHINE trial have been published in the NEJM today. SHINE looked at whether treatment for children with minimal TB could be reduced from 6 months to 4 months. It found that the four month treatment was as good as the standard six months treatment for children with minimal TB
Available in English, French and Spanish
ecancer has just published a comprehensive set of guidelines for paediatric cancer surgery, applicable to low and high resource settings across the world. You can read the guidelines online The guidelines have been developed by the International Society of Paediatric Surgical Oncology (IPSO) with... more
Available in English, French and Spanish
The Early Essential Newborn Care Pocket Guide was developed by the WHO Regional Office for the Western Pacific for introducing and scaling-up Early Essential Newborn Care. This step-by-step Guide is intended to provide a portable and practical summary of the up-to-date global evidence for newborn ca... more
Newborn Resuscitation Algorithm
WHO’s Essential Medicines List and List of Essential Diagnostics are core guidance documents that help countries prioritize critical health products that should be widely available and affordable throughout health systems. The updated Essential Medicines List adds 23 medicines for children.
Handbook 1
Handbook 2
Updated June 2021
The paper provides the rationale for these recommendations, which are based on analyses of data from the TRACT trial.
7 June 2022. To treat complications associated with measles: severe complications with module 1 (50 cases) and mild complications with module 8 (20 cases). The new measles kit 2021 is designed to prepare for and support the treatment of non-severe and severe measles cases during outbreaks. The kit ... more
Abridged version. In this abridged version of the Evidence-based Clinical Practice Guidelines for the Follow-Up of at-risk neonates, we provide recommendations for the care of newborns up to 2 years of age, corresponding to the first phase of their follow-up. The recommendations are intended for all... more
Versión abreviada. En esta versión abreviada de las Directrices de práctica clínica basadas en la evidencia para el seguimiento de recién nacidos en riesgo se brindan recomendaciones para la atención de recién nacidos hasta los 2 años y corresponden a la primera fase de su seguimiento. Las r... more
Compilation of campaign materials Accessed on 29 September 2020