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Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map

Van Katwyk, S. R.; Grimshaw, J. M.; et al (2019) C2

BACKGROUND: Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to reduce antimicrobial overuse. A systematic evidenc...e map can support governments in making evidence-informed decisions about implementing programs to reduce AMR, by identifying, describing, and assessing the full range of evaluated government policy options to reduce antimicrobial use in humans. METHODS AND FINDINGS: Seven databases were searched from inception to January 28, 2019, (MEDLINE, CINAHL, EMBASE, PAIS Index, Cochrane Central Register of Controlled Trials, Web of Science, and PubMed). We identified studies that (1) clearly described a government policy intervention aimed at reducing human antimicrobial use, and (2) applied a quantitative design to measure the impact. We found 69 unique evaluations of government policy interventions carried out across 4 of the 6 WHO regions. These evaluations included randomized controlled trials (n = 4), non-randomized controlled trials (n = 3), controlled before-and-after designs (n = 7), interrupted time series designs (n = 25), uncontrolled before-and-after designs (n = 18), descriptive designs (n = 10), and cohort designs (n = 2). From these we identified 17 unique policy options for governments to reduce the human use of antimicrobials. Many studies evaluated public awareness campaigns (n = 17) and antimicrobial guidelines (n = 13); however, others offered different policy options such as professional regulation, restricted reimbursement, pay for performance, and prescription requirements. Identifying these policies can inform the development of future policies and evaluations in different contexts and health systems. Limitations of our study include the possible omission of unpublished initiatives, and that policies not evaluated with respect to antimicrobial use have not been captured in this review. CONCLUSIONS: To our knowledge this is the first study to provide policy makers with synthesized evidence on specific government policy interventions addressing AMR. In the future, governments should ensure that AMR policy interventions are evaluated using rigorous study designs and that study results are published. more

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A policy advocacy guide on sexual reproductive health and rights (SRHR) for young key populations (YKPS)

S. Nyaude; O. Odumosu; J.Mphande; et al. AMSHeR (American Men for sexual Health & Rights); Children & AIDS (2018) C2

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Dietary patterns and nutritional status of HIV-infected children and adolescents in El Salvador: A cross-sectional study

R. Martín-Cañavate; M. Sonego; M. J. Sagrado; et al. PLOS ONE (2018) CC

PLOS ONE | https://doi.org/10.1371/journal.pone.0196380 May 15, 2018

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Trastorno de personalidad límite en adolescentes

L. Cailhol; L. Gicquel; J.-P. Raynaud IACAPAP (2018) C2

Otros trastornos Capítulo H.4 Editores: Laura Borredá Belda, Matías Irarrázaval & Andres Martin Traductores: Sara Diego Castaño, Laura Álvarez Bravos, Rebeca Santonja & Beatriz Ortega

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Community health worker perspectives on a new primary health care initiative in the Eastern Cape of South Africa

Austin-Evelyn K, Rabkin M, Macheka T, Mutiti A, Mwansa-Kambafwile J, Dlamini T, et al. PLoS ONE (2017) CC

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Pocket Guide for Peer Education Program to Reduce TB and HIV Risks in Tanzania Prisons

B. Mboya, P. Maro, J. Gulaka et al. Ministry of Health, Tanzania; AIDSFree (2017) C1

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Traumatic stress and psychological functioning in a South African adolescent community sample

Swain, K.D., Pillay, B.J. & Kliewer, W. South African Journal of Psychiatry (2017) CC

Background: Traumatic stress may arise from various incidents often leading to posttraumatic stress disorder (PTSD). The lifetime prevalence of PTSD is estimated at 1% – 2% in Western Europe, 6% – 9% in North America and at just over 10% in countries exposed to long-term violence. In South Afri... more

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Trauma and PTSD in the WHO World Mental Health Surveys

Kessler, R.C., Aguilar-Gaxiola, S., Alonso, J., et al. European of Psychotraumatology (2017) CC

Objective: To review research on associations of trauma type with PTSD in the WHO World Mental Health (WMH) surveys, a series of epidemiological surveys that obtained representative data on trauma-specific PTSD.

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Nodding syndrome and epilepsy in onchocerciasis endemic regions: comparing preliminary observations from South Sudan and the Democratic Republic of the Congo with data from Uganda

R. Colebunders, A. Hendy, J.L. Mokili, et al. (2016) CC

BMC Res Notes (2016) 9:182 DOI 10.1186/s13104-016-1993-7

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Take Charge! A Reproductive Health Guide for Women with Disabilities

Healy, K.; Panko Reis, J.; M. Martin Access Living; The Empowered Fe Fes (2016) CC

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National Guideline on Maternal and Perinatal Death Surveillance an Response

Dr. Md. A. Hasan; Dr. S. A. J. Md. Musa; Dr. R. Mahmud et al. Ministry of Health & Family Welfare Government of the Peoples Republic of Bangladesh; World Health Organization (WHO); Unicef; et al. (2016) C2

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Using antipsychotic medication for the treatment of schizophrenia in children and adolescents

M. Ferrin; H. Gosney; A. Marconi; J. M. Rey IACAPAP (2016) C2

Other disorders Chapter H.5.1

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An Assessment of Contraceptive Use by Marriage Type among Sexually Active Men in Nigeria: Analysis of the 2013 Demographic and Health Survey.

Asa, S.S., A. Titilayo, and J. A. Kupoluyi. ICF International (2016) C2

DHS Working Papers No. 124

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F4. Reactions aigues et chroniques aux traumatismes chez les enfants et les adolescents

Eric Bui, Bonnie Ohye, Sophie Palitz, Bertrand Olliac, Nelly Goutaudier, Jean-Philippe Raynaud, Kossi B Kounou & Frederick J Stoddard Jr IACAPAP (2015) C1

Dérivant du grec τραῦμα signifiant « blessure », le mot « traumatisme » a été utilisé durant des siècles comme un terme médical désignant « une blessure des tissus vivants causée par un agent externe.» Ainsi, ce n’est qu’en 1889, lorsque Oppenheim fit la première descrip... more

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Borderline personality disorder in adolescents

L. Cailhol; L. Gicquel; J. - P. Raynaud IACAPAP (2015) C2

Other Chapter H.4 2015 edition

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Trauma and Treatment in Early Childhood: A Review of the Historical and Emerging Literature for Counselors

Buss, K.E., Warren, J.M. & Horton, E. The Professional Counselor (TPC) (2015) C1

Young children are especially susceptible to exposure to trauma. Rates of abuse and neglect among this population are staggering. This article presents a review of relevant literature, including research findings specific to early childhood vulnerability to trauma, symptoms associated with traumatic... more

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A Path to Policy - A Blueprint for Community Engagement and Advocacy

M. Allen; E. McCloskey; J. M. Scofield et al. NASTAD (National Alliance of State & Territorial AIDS Directors) (2014) C2

Sept 2014 / nastad.org

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Assessing the Quality of Care in Family Planning, Antenatal, and Sick Child Services at Health Facilities in Kenya, Namibia, and Senegal

Wang, W., Do, M., Hembling, J. & Ametepi, P. (2014) C1

DHS Analytical Studies No. 44 Rockville, Maryland, USA: ICF International.

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Slowing of the HIV Epidemic in Ukraine: Evidence from Case Reporting and Key Population Surveys, 2005–2012

C. R. Vitek; J.-I. Cakalo; Y .V. Kruglov; et al. PLOS One (2014) C2

PLOS ONE | www.plosone.org September 2014 | Volume 9 | Issue 9 | e103657

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Plausible role for CHW peer support groups in increasing care-seeking in an integrated community case management project in Rwanda: a mixed methods evaluation

Langston, A., Weiss, J., Landegger, J., et al. Global Health: Science and Practice (2014) CC

The Kabeho Mwana project (2006–2011) supported the Rwanda Ministry of Health (MOH) in scaling up integrated community case management (iCCM) of childhood illness in 6 of Rwanda’s 30 districts. The project trained and equipped community health workers (CHWs) according to national guidelines. In p... more