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Conceptual and Operational Framework of Onchocerciasis Elimination with Ivermectin Treatment

World Health Organization WHO; African Programme for Onchocerciasis Control APOC (2010) C_WHO
Onchocerciasis used to be an important public health problem in Africa, with over 37 million people infected and millions suffering from debilitating skin disease, terrible itching, impaired vision and blindness. But the epidemiological situation has improved dramatically over the last two decades.... more
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A four-step process for building sustainable access to diagnosis and treatment of Chagas disease

Batista, C.; Forsyth, C.; Herazo, F.; et al. Pan American Journal of Public Health (2019) CC
Over 6 million people worldwide are infected with Trypanosoma cruzi, the protozoan that causes Chagas disease (CD). T. cruzi is transmitted by triatomine insects, congenitally, through uncontrolled blood donations and organ transplants, and via consumption of food or drink contaminated by triatomi... more
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Congenital Chagas disease: Updated recommendations for prevention, diagnosis, treatment, and follow-up of newborns and siblings, girls, women of childbearing age, and pregnant women

Carlier, Y.; Altcheh, J.; Angheben, A. et al. PLOS Neglected Tropical Diseases (2019) CC
In 2005, the World Health Organization (WHO) recognized Chagas disease (CD; Trypanosoma cruzi infection) as a neglected tropical disease (NTD) [1] and included it into the global plan to combat NTDs [2]. The Target 3.3 of the United Nations Sustainable Development Goals (UN/SDG) aims at ending the e... more
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Guidelines of Chagas Disease for the Diagnosis and Treatment

Luquetti, A.; Tavares, S. Pan American Health Organization PAHO - World Health Organization WHO (2019) C_WHO
he Pan American Health Organization (PAHO) would like to thank the group that developed these guidelines for the tremendous work, quick response, and commitment they demonstrated in this process. We would like to especially recognize the following doctors: Roberto Chuit, Jaime Altcheh, Alejandro Luq... more
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Efficacy and Safety of Pafuramidine versus Pentamidine Maleate for Treatment of First Stage Sleeping Sickness in a Randomized, Comparator-Controlled, International Phase 3 Clinical Trial

Pohlig G, Bernhard SC, Blum J, Burri C, Mpanya A, et al. PLOS Neclected Tropical Diseases (2016) CC
This was a Phase 3, multi-center, randomized, open-label, parallel-group, active control study where 273 male and female patients with first stage Trypanosoma brucei gambiense HAT were treated at six sites: one trypanosomiasis reference center in Angola, one hospital in South Sudan, and four hospita... more
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Waiting for a success story in prevention, control and treatment of Chagas disease in non-endemic countries

Bartoloni, A. Memorias do Instituto Oswaldo Cruz (2022) CC
Chagas disease (CD) is endemic in the Americas, being present in 21 countries, where it affects about 6 million people.(1) With such relevant numbers of people affected and disability adjusted life years lost, CD is a poverty-related and poverty-promoting disease. Although data describe a relevan... more
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What is Dengue? Causes, Signs and Symptoms, Diagnosis and treatment.

Medical Centric Medical Centric (2018) CC
Chapters 0:00 Introduction 0.27 Causes of Dengue Fever 1:09 Signs and Symptoms of Dengue Fever 2:30 Dengue Hemorrhagic Fever 3:53 Diagnosis of Dengue Fever 4:10 Treatment of Dengue Fever Dengue fever is a mosquito-borne tropical disease caused by the dengue virus. Symptoms typically beg... more
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Targeting the Mycobacterium ulcerans cytochrome bc1:aa3 for the treatment of Buruli ulcer

Scherr, N.; R. Bieri, S.S. Thomas, et al. (2018) CC
Nat Commun 9, 5370 (2018). https://doi.org/10.1038/s41467-018-07804-8. Mycobacterium ulcerans is the causative agent of Buruli ulcer, a neglected tropical skin disease that is most commonly found in children from West and Central Africa. Despite the severity of the infection, therapeutic options are... more
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Cross-Cultural Variance of Schizophrenia in Symptoms, Diagnosis and Treatment

Banerjee, A. (2012) C2
The Georgetown Undergraduate Journal of Health Services (2), 2012.
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Consolidated guidelines on HIV, viral hepatitis and STI prevention, diagnosis, treatment and care for key populations

World Health Organization WHO (2022) C_WHO
The Consolidated guidelines on HIV, viral hepatitis and STI prevention, diagnosis, treatment and care for key populations outline a public health response for 5 key populations (men who have sex with men, trans and gender diverse people, sex workers, people who inject drugs and people in prisons and... more
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Investing in drug-resistant tuberculosis household contact management and preventive treatment

Hussain.H.; Malik, A. A. The Lancet (2022) CC
Preventing tuberculosis infection from progressing to tuberculosis disease is a crucial component of the goal to eliminate tuberculosis. When deciding on the use of tuberculosis preventive therapy among household contacts, policy makers regularly ask questions, such as whether tuberculosis preventiv... more
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The use of rectal artesunate as a pre-referral treatment for severe P. falciparum malaria: information note

World Health Organization WHO (2022) C_WHO
Available in English, French and Spanish
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Breast cancer A guide for journalists on breast cancer and its treatment

Roche Roche (2021) C1
Each year more than one million women are diagnosed with breast cancer worldwide over half of whom will die from the disease. Breast cancer is the most common cancer and the leading cause of cancer death for women
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Advisory for Rational use of Remdesivir for COVID-19 Treatment

Ministry of Health& Family Welfare, Goverment of India (2021) CC
The purpose of this document is to stop to irrational use/ over prescription of this reserve/ experimental/ emergency use authorisation drug Remdesivir. For this reason, Joint Monitoring Group under Chairmanship of DGHS took into consideration findings of the followi... more
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WHO Sciene in 5 Episode #32 - Equity in vaccines, treatment and tests

World Health Organization WHO (2021) C_WHO
1 April 2021 In our unequal world, how does inequity impact our fight against COVID-19? How can we address it? WHO’s Dr Mariângela Simao explains in Science in 5 this week.
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A situational analysis of programmatic management of TB preventive treatment in the WHO South-East Asia Region

World Health Organization WHO (2020) C_WHO
Tuberculosis (TB) prevention is essential for reaching the End TB targets in the South-East Asia Region (SEAR) of World Health Organization (WHO)1. The targets of 80% reduction in TB incidence rate and 90% reduction in TB mortality by 2030 (compared to 2015 levels) can be achieved only with addition... more
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WHO recommendation on umbilical vein injection of oxytocin for the treatment of retained placenta

World Health Organization (2020) C_WHO
The recommendation in this document thus supersedes the previous WHO recommendation for the prevention of PPH as published in the 2012 guideline, WHO recommendations for the prevention and treatment of postpartum haemorrhage.
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Standard operating procedures for caregivers in COVID-19 treatment centres
recommended

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C1
Caregivers provide invaluable service and support to patients in health facilities. In many health systems, caregivers (often members of the patient’s family or friends) are responsible for providing basic care for a patient, including providing food and drinks, cleaning clothes and bed linen, as ... more
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Recommendation regarding the use of Ivermectin as a treatment for COVID-19
recommended

Pan American Health Organization PAHO, World Health Organization WHO (2020) C_WHO
A recent study informed that ivermectin was successfully used in vitro for the treatment of SARS-CoV-2 in experimentally infected cells and two preprint publications on observational clinical studies reported the apparent utility of ivermectin to treat patients with COVID-19 needing mechanical venti... more
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Statement on herbal remedies and medicines for prevention and treatment of COVID-19

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C1
This statement aims to provide guidance and recommendation to African Union Member States in responding to the following questions: What should countries do when announcing identification of a herbal remedy or medicine? What are the implications for the rest of the continent?