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Primary Health Care As An Enabler For “Ending The Epidemics” Of High-Impact Communicable Diseases

World Health Organization WHO (2018) C_WHO

The Millennium Development Goals (MDGs) showed that global commitment and collective action could significantly reduce the disease burdens of three deadly communicable diseases: HIV/AIDS, tuberculosis (TB) and malaria. The MDGs helped focus efforts on these three deadly diseases and leveraged ... more

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Tuberculosis en el Perú: situación epidemiológica, avances y desafíos para su control

Alarcón, V.; E. Alarcón, C. Figuero, et al. (2017) CC

Revista Peruana de Medicina Experimental y Salud Pública 2017 Vol 34 (2) En el presente artículo se desarrolla la situación epidemiológica de la TB en el Perú al 2015, los avances en su control, de acuerdo a tres enfoques: biomédico, de gestión pública y de determinantes sociales de la salu... more

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Características epidemiológicas de tuberculosis pulmonar en establecimiento penitenciario de varones de Trujillo – Perú

Hidalgo, R.; L.A. Chimoy and C. Tunoque (2017) C1

Acta Med Peru. 2017;34(3):182-7; El objetivo del presente trabajo es conocer la magnitud del problema de la TB y sus principales características epidemiológicas en la población del penal de varones de penal de varones de Trujillo, que sirva de base para plantear las mejores soluciones terapéutic... more

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IMAI district clinician manual: hospital care for adolescents and adults: guidelines for the management of illnesses with limited-resources. Vol. 2
recommended

World Health Organization WHO (2011) C_WHO

The manual is written for clinicians working at the district hospital (first-level referral care) who diagnose and manage sick adolescents and adults in resource constrained settings. It aims to support clinical reasoning, and to provide an effective clinical approach and protocols for the managemen... more

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Guidelines for the Prevention of Tuberculosis in Health Care Facilities in Resource-limited Settings

World Health Organization WHO (1999) C_WHO

These guidelines are designed for settings with limited resources to provide inexpensive and effective control strategies for prevention of TB transmission in health care workers (HCW).

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Management of tuberculosis and HIV coinfection

R. Colebunders; M. Danilovits; K. Erdahl et al. World Health Organization (Europe) (2013) C_WHO

This publication is an updated version of the Management of Tuberculosis and HIV Coinfection clinical protocol released in 2007 by the WHO Regional Office for Europe. It is intended for all health care workers involved in preventing, diagnosing, treating and caring for people living with TB and HIV ... more

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Integrating the prevention and control of noncommunicable diseases in HIV/AIDS, tuberculosis, and sexual and reproductive health programmes

World Health Organization (WHO) World Health Organization (WHO) (2023) C_WHO

The WHO document "Integrating the prevention and control of noncommunicable diseases in HIV/AIDS, tuberculosis, and sexual and reproductive health programmes: implementation guidance" provides a framework for integrating noncommunicable diseases (NCDs) into existing health programs for HIV/AIDS, tub... more

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Pathogenesis of chronic obstructive pulmonary disease: An African perspective

Allwood, B.; Calligaro, G. South African Medical Journal (SAMJ) (2015) CC2

The article discusses the significant impact of chronic obstructive pulmonary disease (COPD) as a global health issue, with cigarette smoking as the main risk factor. However, in developing countries, the causes of COPD are often multifactorial, involving environmental tobacco smoke, biomass fuel sm... more

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UNAIDS Terminology Guidelines

UNAIDS (2024) CC

Language influences the way we think, how we perceive reality, and how we behave. With respect to HIV, language can embody stigma and discrimination, which impacts access to testing, acquisition of HIV, and engagement with treatment. Language plays a role in supporting respect and empowerment of ind... more

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African Union AMR Landmark Report: Voicing African Priorities on the Active Pandemic

Africa Center for Disease Control and Prevention (2024) CC

Antimicrobial resistance (AMR) has emerged as a leading cause of death in the African region, surpassing fatalities from malaria, HIV, and TB. In response to this critical threat, the region has adopted the AMR Global Action Plan and the African Union Framework for Antimicrobial Resistance Control 2...020 – 2025, which is tailored to meet the specific needs of African nations through a coordinated approach. While most countries in the region have developed and prioritized National Action Plans (NAPs) to tackle AMR, the overall response remains inadequate given the magnitude of the threat, which endangers human, animal, environmental, aquatic, and plant health. Africa bears a significant burden of infectious diseases, accounting for approximately 95% of malaria deaths, 70% of people living with HIV, and 25% of TB deaths globally. In 2019, AMR was linked to approximately 55,000 deaths from HIV, 30,000 from malaria, and 255,000 overall. Major drivers of AMR in the region include the overuse and misuse of antimicrobials in human and food systems, migration, suboptimal vaccination rates, and environmental contamination from hospital and pharmaceutical effluents. Additionally, there is a lack of access to quality-assured antimicrobials and diagnostics, compounded by inadequate knowledge about AMR. Unlike high-income countries, where indiscriminate antimicrobial use is the primary factor driving AMR, African countries face additional challenges, including a lack of access to clean and safe water, poor Water, Sanitation, and Hygiene (WASH) programs, inadequate infection prevention measures, and suboptimal vaccinations for preventable diseases. One in three hospitals in the region lacks clean, safe running water, and one in eight people defecate openly due to inadequate sanitation. Investments in WASH, infection prevention, and biosecurity could save approximately 700,000 lives annually. Addressing AMR in Africa requires a comprehensive, multi-sectoral approach involving the entire society. Sustainable access to antimicrobials, including antibiotics, vaccines, and therapeutics, is crucial, as lack of access leads to more morbidity and mortality than AMR itself. Support for the region should focus on preventing infections, strengthening health and food systems, developing human resources, ensuring sustainable access to diagnostics and therapeutics, and investing in laboratory infrastructure to support surveillance and data generation. more

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SARS-CoV-2 antigen-detecting rapid diagnostic tests: An implementation guide

World Health Organization WHO (2021) C_WHO

This guide provides an overview of the major elements that must be considered before, during and after the implementation of antigen-detecting rapid diagnostic tests (Ag-RDTs) for SARS-CoV-2. This guide is complementary to policy guidance issued by the World Health Organization (WHO). The guide may ... more

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Adherence interventions and outcomes of tuberculosis treatment: A systematic review and meta-analysis of trials and observational studies

Alipanah N, Jarlsberg L et al. (2018) CC

We systematically reviewed Medline as well as the references of published review articles for relevant studies of adherence to multidrug treatment of both drug-susceptible and drug-resistant TB through February 3, 2018. We included randomized controlled trials (RCTs) as well as prospective and retro... more

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Diagnosis and Treatment Outcomes of Tuberculosis in Relation to Gender and HIV Status in South Benin

Ablo Prudence Wachinou, Serge Ade, Gildas Agodokpessi, Berenice Awanou, Dissou Affolabi, Wilfried Bekou, Marius Esse, Gabriel Ade, Severin Anagonou, Anthony D. Harries,1Programme National contre la Tuberculose (PNT), Cotonou, Bénin Journal of Tuberculosis Research (2017) C2

Journal of Tuberculosis Research, 2017, 5, 189-200 Background: In Benin, little is known about the influence of both gender and HIV-status on diagnostic patterns and treatment outcomes of Tuberculosis (TB) patients. Objective: To assess whether differences in gender and HIV status affect diagn... more

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Maldives National Action Plan for Containment of Antimicrobial Resistance 2017-2022

Maldives Food and Drug Authority Ministry of Health (2017) C2

Maldives has made significant strides in the area of infectious disease prevention and control. This is exemplified by elimination of malaria from Maldives in 2015 and successes in TB control. In addition, Maldives is a front runner in infectious disease prevention through successful water, sanitati... more

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Consolidated guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection
recommended

World Health Organization WHO (2016) C_WHO

2nd edition. These guidelines provide guidance on the diagnosis of human immunodeficiency virus (HIV) infection, the use of antiretroviral (ARV) drugs for treating and preventing HIV infection and the care of people living with HIV. They are structured along the continuum of HIV testing, prevention,... more

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Standard Operating Procedures on Viral Load Monitoring for ICAP Clinical Staff and Health Care Workers: A Template Document for Country Adaptation

ICAP (2016) C1

Version 1.1 July 2016
The purpose of this document is to describe standard operating procedures for viral load monitoring, including the schedule for viral load testing when used for routine monitoring of children, adolescents and adults on ART; interpretation of results; patient management; an... more

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Field Trials of Health Interventions: A Toolbox

Peter G. Smith, Richard H. Morrow, and David A. Ross (2015)

This version of Field Trials of Health Interventions includes seven new chapters on conducting systematic literature reviews, trial governance, preliminary studies and pilot testing, budgeting and accounting, intervention costing and economic analysis, and Phase IV studies. Before new interventions... more

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Primary Care 101
recommended

Dept. of Health, Republic of South Africa (2013) C1

Symptom-based integrated approach to the adult in primary care. Primary Care 101 is a comprehensive clinical practice guideline that aims to equip nurses and other clinicians to diagnose and manage common adult conditions at primary level. Tb; HIV; Asthma/COPD; cardiovascular disease; diabetes; M... more

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Epidemiology and Challenges of Managing COPD in sub-Saharan Africa

Magitta, N.F.; Sciences, A. Acta Scientific Medical Sciences (2018) CC2

There is paucity of data on the burden and specific drivers operative in the pathogenesis of chronic obstructive pulmonary disease (COPD) in the African setting and populations. Lack of awareness and inadequate knowledge on the aetio-pathogenesis of the disease together with inadequate capacity for ... more

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Achieving Control of Asthma in Children in Africa (ACACIA): protocol of an observational study of children’s lung health in six sub-Saharan African countries

Mosler, G.; Oyenuga, V.; Addo-Yobo, E. et al. BMJ Open (2020) CC

Little is known about asthma control in the rising number of African children who suffer from this condition. The Achieving Control of Asthma in Children in Africa (ACACIA) study is an observational study collecting evidence about paediatric asthma in urban areas of Ghana, Malawi, Nigeria, South Afr... more

IMAI district clinician manual: hospital care for adolescents and adults: guidelines for the management of illnesses with limited-resources. Vol. 2 recommended

Consolidated guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection recommended

Primary Care 101 recommended

IMAI district clinician manual: hospital care for adolescents and adults: guidelines for the management of illnesses with limited-resources. Vol. 2
recommended

Consolidated guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection
recommended

Primary Care 101
recommended