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Screening for cardiovascular disease risk and subsequent management in low and middle income countries: challenges and opportunities

Bovet, P.; Chiolero, A.; Paccaud, F. et al. Public Health Reviews (2015) CC

Background: Cardiovascular disease (CVD), mainly heart attack and stroke, is the leading cause of premature mortality in low and middle income countries (LMICs). Identifying and managing individuals at high risk of CVD is an important strategy to ... prevent and control CVD, in addition to multisectoral population-based interventions to reduce CVD risk factors in the entire population. Methods: We describe key public health considerations in identifying and managing individuals at high risk of CVD in LMICs. Results: A main objective of any strategy to identify individuals at high CVD risk is to maximize the number of CVD events averted while minimizing the numbers of individuals needing treatment. Scores estimating the total risk of CVD (e.g. ten-year risk of fatal and non-fatal CVD) are available for LMICs, and are based on the main CVD risk factors (history of CVD, age, sex, tobacco use, blood pressure, blood cholesterol and diabetes status). Opportunistic screening of CVD risk factors enables identification of persons with high CVD risk, but this strategy can be widely applied in low resource settings only if cost effective interventions are used (e.g. the WHO Package of Essential NCD interventions for primary health care in low resource settings package) and if treatment (generally for years) can be sustained, including continued availability ofaffordable medications and funding mechanisms that allow people to purchase medications without impoverishing them (e.g. universal access to health care). Thisalso emphasises the need to re-orient health systems in LMICs towards chronic diseases management. Conclusion: The large burden of CVD in LMICs and the fact that persons with high CVD can be identified and managed along cost-effective interventions mean that health systems need to be structured in a way that encourages patient registration, opportunistic screening of CVD risk factors, efficient procedures for the management of chronic conditions (e.g. task sharing) and provision of affordable treatment for those with high CVD risk. The focus needs to be in primary care because that is where most of the population can access health care and because CVD programmes can be run effectively at this level. more

WHO mhGAP Guideline update
recommended

WHO WHO (2015) C_WHO

Update of the Mental Health Gap Action Programme (mhGAP) Guideline for Mental, Neurological and Substance use Disorders May 2015

Revised National Guidelines on Mpox

Wasif Malik, M.; et al. National Institute of Health, Pakistan (2024) CC

This document serves to provide interim guidance/ recommendations to carry out mpox surveillance activities mainly case investigation, contact tracing and isolation. For the development of this docu ... more

Multi-country outbreak of cholera External Situation Report # 23, published 20 February 2025

World Health Organisation (WHO) (2025) C_WHO

Multi-country outbreak of cholera External Situation Report # 23, published 20 February 2025

WHO/UNICEF Strategic Plan for Polio Outbreak Response in the Middle East

The Polio Global Eradication Initiative WHO (2013)

THE SYRIAN ARAB REPUBLIC, IRAQ, JORDAN, LEBANON, TURKEY, WEST BANK AND GAZA STRIP, EGYPT

International Assistance for HIV/AIDS in the Developing World: Taking Stock of the G8, Other Donor Governments and the European Commission

Kates J. Kaiser Family Foundation (2006) CC

As the Group of Eight (G8) world leaders meet in Saint Petersburg, Russia for this year’s G8 Summit, it is important to take stock of internation ... more

Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map

Van Katwyk, S. R.; Grimshaw, J. M.; et al (2019) C2

BACKGROUND: Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to ... reduce antimicrobial overuse. A systematic evidence map can support governments in making evidence-informed decisions about implementing programs to reduce AMR, by identifying, describing, and assessing the full range of evaluated government policy options to reduce antimicrobial use in humans. METHODS AND FINDINGS: Seven databases were searched from inception to January 28, 2019, (MEDLINE, CINAHL, EMBASE, PAIS Index, Cochrane Central Register of Controlled Trials, Web of Science, and PubMed). We identified studies that (1) clearly described a government policy intervention aimed at reducing human antimicrobial use, and (2) applied a quantitative design to measure the impact. We found 69 unique evaluations of government policy interventions carried out across 4 of the 6 WHO regions. These evaluations included randomized controlled trials (n = 4), non-randomized controlled trials (n = 3), controlled before-and-after designs (n = 7), interrupted time series designs (n = 25), uncontrolled before-and-after designs (n = 18), descriptive designs (n = 10), and cohort designs (n = 2). From these we identified 17 unique policy options for governments to reduce the human use of antimicrobials. Many studies evaluated public awareness campaigns (n = 17) and antimicrobial guidelines (n = 13); however, others offered different policy options such as professional regulation, restricted reimbursement, pay for performance, and prescription requirements. Identifying these policies can inform the development of future policies and evaluations in different contexts and health systems. Limitations of our study include the possible omission of unpublished initiatives, and that policies not evaluated with respect to antimicrobial use have not been captured in this review. CONCLUSIONS: To our knowledge this is the first study to provide policy makers with synthesized evidence on specific government policy interventions addressing AMR. In the future, governments should ensure that AMR policy interventions are evaluated using rigorous study designs and that study results are published. more

An overview of heart failure in low- and middle-income countries

Agbor, V.N.; Ntusi, N.A.B.; Noubiap, J.J. Cardiovascular Diagnosis and Therapy (2020) CC

Heart failure (HF) is a global public health concern with disproportionate socioeconomic, morbidity and mortality burden on low- and middle-income countries (LMICs). This review summarises contemporary data on ... more

National Action Plan for Combating Antimicrobial Resistance In the Hashemite Kingdom of Jordan (2018-2022)

Ministry of Health Jordan (2018) C_WHO

The objectives of NAP are aligned with the global action plan based on national needs and priorities. The emphasis is on One ... more

Mass Casualty Management Systems. Strategies and guidelines for building health sector capacity

Health Action in Crisis Word Health Organization (2007)

Disaster planning - organization and administration. 2.Emergency medical services - methods. 3.Emergency medical services - organization and administration. 4.Emergencies. 5. ... more

Trends in Maternal Mortality: 1990 to 2015

WHO, UNICEF, UNFPA, World Bank Group and the United Nations Population Division (2015) C_WHO

Guideline for Preventive Chemotherapy for the Control of Taenia solium Taeniasis

Pan American Health Organisation PAHO (2021) C_WHO

The larval stage of the parasite Taenia solium can encyst in the central nervous system causing neurocysticercosis, which is ... more

National Action Plan of the Islamic Republic of Iran for combating antimicrobial resistance

Ministry of Health and Medical Education Iran (2016) C_WHO

Antimicrobial resistance is one of the most important threats to the health worldwide. Antimicrobial resistance or drug resistance is ... more

Promotion, prevention and protection: interventions at the population- and community-levels for mental, neurological and substance use disorders in low- and middle-income countries

I. Petersen; , S. Evans‐Lacko; M. Semrau; et al. International Journal of Mental Health Systems; BioMed Central (2016) CC

Petersen et al. Int J Ment Health Syst (2016) 10:30 DOI 10.1186/s13033-016-0060-z

Roadmap to prevent and combat drug-resistant tuberculosis

World Health Organization Europe (2011) C_WHO

Child and adolescent mental health policies and plans

Dr M.Funk; M. Belfer; N. Drew; et al. World Health Organization (2005) C_WHO

Mental Health Policy and Service Guidance Package Languages: Arabic, English, French, Chinese, Russian

The Role of Laboratories and Blood Banks in Disaster Situations

Pan American Health Organization (2001) C_WHO

Health in 2015: from MDGs, Millennium Development Goals to SDGs, Sustainable Development Goals.

Ties Boerma, Colin Mathers, Carla AbouZahr, Somnath Chatterji, Daniel Hogan and Gretchen Stevens World Health Organization (2015) C_WHO

Integrating Mental Health into Primary Care

M. Funk; G. Ivbijaro World Health Organization; WONCA (2008) C_WHO

A Global Perspective

The global climate in 2015–2019

World Meteorological Organization (2019) CC

Compared to the previous five-year assessment period 2011–2015, the current five-year period 2015–2019 has seen a continued increase in carbon dioxide (CO2 ) emissions and an accelerated increas ... more