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Publication Years
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Populations affected by emergencies are continually at risk of outbreaks of epidemic-prone diseases and other public health hazards. This operational guidance aims to guide decision-making on when and how to implement and strengthen Early Warning Alert and Response (EWAR) in preparation for and resp
...
onse to emergencies. Each module aims to provide updated operational guidance for EWAR practices, which may be more easily understood and applied during emergencies. Through its application, this operational guidance aims to contribute to:
- earlier detection of acute public health events
- earlier and more effective response
- reduced impact of emergencies on health
- increased trust of the population in the (public) health system
- fulfilling our collective commitments to the International Health Regulations (IHR,
2005).
This guidance was developed jointly by 69 experts from more than 20 organizations from global level to country level.
more
This report examines how clinical trials contribute to environmental impacts and outlines key considerations for integrating environmental sustainability into trial design, conduct and oversight. It explores the carbon footprint and resource use associated with clinical research activities – inclu
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ding site operations, participant travel, supply chains, data management and waste – and highlights how these impacts intersect with climate change risks to health systems and research infrastructure.
more
The document “Guidelines for the Investigation and Control of Disease Outbreaks” provides practical guidance for public health professionals on how to detect, investigate, and manage outbreaks of communicable diseases. It describes the key steps of outbreak investigation, including confirming th
...
e outbreak, establishing a case definition, collecting epidemiological and laboratory data, identifying the source and mode of transmission, and implementing control measures. The guidelines also explain how to organize outbreak response teams, communicate findings, and document results in outbreak reports. Overall, the document aims to support systematic and effective outbreak investigations in order to control disease spread and protect public health.
more
The document “Interim Guidelines – Infectious Disease Outbreak Response and Analytic System” published by the United Nations provides a framework for how UN missions and organizations should detect, report, analyze, and respond to infectious disease outbreaks. It outlines a coordinated system
...
for monitoring health threats, collecting and analyzing epidemiological data, and guiding decision-making during outbreaks. The guidelines define roles and responsibilities for different actors within the UN system, describe procedures for outbreak reporting and risk assessment, and emphasize early detection, information sharing, and coordinated response measures to protect personnel and maintain operational continuity during public health emergencies.
more
World Health Organization (2018). A practical guide for developing and conducting simulation exercises to test and validate pandemic influenza preparedness plans.
The document “Pandemic Planning Response Guide” provides guidance for organizations on how to prepare for, respond to, and recover from a pandemic. It explains what a pandemic is and emphasizes the importance of advance planning to reduce disruptions to operations. The guide presents a structure
...
d response framework based on different pandemic phases—from early alert and pre-pandemic preparation to the active pandemic phase and the recovery period afterward. For each phase, it outlines triggers, strategic actions, and practical tasks organizations should implement, such as establishing communication plans, ensuring business continuity, supporting remote work, managing supply chains, and protecting employee health and safety. In addition, the guide discusses key planning considerations like crisis communication, mental health impacts, transportation disruptions, and workforce management. Overall, the document serves as a practical template to help organizations maintain essential services and adapt their operations during a global health emergency.
more
The Health Emergency and Disaster Risk Management
Chan E.Y.Y., Huang Z., Hung K.K.C. et al
United Nations Office for Disaster Risk Reduction UNDRR
(2022)
CC
An emerging framework for achieving synergies among the Sendai Framework, the 2030 Agenda for Sustainable Development, the New Urban Agenda and the Paris Agreement. This paper discusses the potential of the Health Emergency and Disaster Risk Management (Health-EDRM) Framework in promoting syne
...
rgies in pursing risk- resilient sustainable development pathways via conceptual analysis of the key roles of health and Health-EDRM in the major international risk-resilient and sustainable development agendas of the Sendai Framework, the 2030 Agenda for Sustainable Development, the New Urban Agenda and the Paris Agreement. It first analyses the Health-EDRM Framework, which is a comprehensive, systematic, cross-sectoral, and interdisciplinary endeavour of the World Health Organization and its health and non- health partners. The four key international risk-resilient and sustainable development agendas are then analysed in detail to explore how they can be interlinked and synergised under the Health-EDRM Framework.
more
Guide to revision of national pandemic influenza preparedness plans - Lessons learned from the 2009 A(H1N1) pandemic
Brown C., Ciotti M., Hegermann-Lindencrone M., et al
European Centre for Disease Prevention and Control (ECDC), WHO Regional Office for Europe
(2017)
C_WHO
The document “Guide to revision of national pandemic influenza preparedness plans – Lessons learned from the 2009 A(H1N1) pandemic” provides guidance for countries on how to improve and update their national pandemic preparedness plans. It is based on lessons learned from the 2009 influenza pa
...
ndemic and aims to help governments strengthen their readiness for future pandemics. The report outlines key components of effective pandemic planning, including risk assessment, coordination between sectors, communication strategies, healthcare system preparedness, vaccination and antiviral strategies, and business continuity planning. It also emphasizes the importance of international cooperation and flexible planning that can adapt to different pandemic scenarios. Overall, the guide serves as a framework to support countries in developing stronger, more coordinated responses to future influenza pandemics.
more
medRxiv preprint;https://doi.org/10.64898/2026.02.18.26346597. This model application demonstrates that the sudden cessation of USAID and CDC
commitments in the largest HIV epidemic in the world leads to increased incidence and mortality
and threatens decades of progress in KZN, South Africa. Rest
...
oring funding within 12 months
and increasing efficiency of HIV interventions can reestablish KwaZulu Natal province, South
Africa’s trajectory toward EHE goals.
more
Female genital mutilation (FGM) is a human rights violation deeply rooted in gender inequality and discrimination. FGM violates various human rights under international human rights law including, among others, the rights to equality, life and health and the rights to be free from discrimination, to
...
rture and cruel, inhuman and degrading treatment. The failure by States to end this harmful practice against women and girls is a violation of States’ obligations to respect, protect and fulfil the enjoyment of all human rights. These obligations are accompanied by certain human rights accountability mechanisms that are critical in holding States to account for implementing their international and regional human rights obligations and commitments
more
The document is a practical toolkit that provides guidance for healthcare facilities on how to prepare for emergencies, including pandemics and other disasters. It explains how to conduct risk assessments using an all-hazards approach, helping facilities identify potential threats such as natural di
...
sasters, technical failures, and disease outbreaks. The text outlines how to develop emergency preparedness and pandemic plans, including key elements like communication, staffing, resource management, and coordination with local, state, and federal authorities. It also describes the four phases of emergency management—mitigation, preparedness, response, and recovery—and emphasizes continuous evaluation and improvement. Overall, the document aims to help healthcare organizations ensure continuity of care and protect patients and staff during emergencies.
more
This guide aims to support the implementation of evidence-based practices to reduce morbidity and mortality due to postpartum haemorrhage (PPH). Implementation is a multidisciplinary process that requires engagement from multiple stakeholders. Furthermore, implementation can and should be pursued in
...
a systematic and evidence-based manner.
This Implementation guide presents a structured process that will aid countries in their efforts to incorporate the latest PPH recommendations into national PPH guidelines and clinical practice.
more
The document provides practical guidelines for conducting a national disaster risk assessment, developed by the United Nations Office for Disaster Risk Reduction. It emphasizes the importance of understanding disaster risk as a foundation for effective disaster risk management and sustainable develo
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pment. The guidelines outline a structured process that includes preparing and scoping the assessment, conducting risk analysis, and using the results to inform policy and decision-making. They promote a comprehensive, multi-hazard approach that considers vulnerabilities, exposure, and capacities, while encouraging collaboration among governments, experts, and stakeholders. Overall, the document aims to help countries build stronger systems for assessing and managing risks, thereby enhancing resilience and reducing the impacts of disasters.
more
Artificial intelligence for tuberculosis control: a scoping review of applications in public health
Menon, S.; and K. Ghislein Kuro
(2025)
J Glob Health. 2025;15:04192. This scoping review highlights the potential of AI-driven predictions in national TB programmes to enhance diagnostics, track trends, and strengthen public health surveillance. While promising for reducing transmission and support-
ing TB care in low-resource settings,
...
these models require large-scale validation to ensure real-world applicability, especially for high-risk groups
more
This multi-hazard Health Emergency Alert and Response Framework provides guidance for coordinating emergency response in countries, under the global Health Emergency Preparedness, Resilience and Response (HEPR) framework. It outlines the public health functions, coordination systems and actions need
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ed for effective local, sub-national and national response to a broad range of health emergencies, including disasters. The audience for this framework is the primary national and sub-national authorities with the designated responsibility for health emergency coordination.
more
This guidance addresses one type of generative AI, large multi-modal models (LMMs), which can accept one or more type of data input and generate diverse outputs that are not limited to the type of data fed into the algorithm. It has been predicted that LMMs will have wide use and application in heal
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th care, scientific research, public health and drug development. LMMs are also known as “general-purpose foundation models”, although it is not yet proven whether LMMs can accomplish a wide range of tasks and purposes.
more
The Gender Assessment Tool for National HIV Responses (Gender Assessment Tool) is intended to assist countries in assessing their HIV epidemic, context and response through an intersectional gender lens, with the aim of strengthening gender-transformative, equitable and rights-based HIV responses. T
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he 2025 tool places greater emphasis on cost-effectiveness, alignment with national plans, integration and sustainability. Together with a new costing tool and monitoring and evaluation plan template, it is designed to inform the development of country investment cases, funding requests to the Global Fund to Fight AIDS, Tuberculosis and Malaria, and other key national opportunities.
more
The 2026 outlook remains concerning. Without sustained support, health needs will remain acute. Disease outbreak risks persist amid degraded surveillance. Interagency planning indicates 10.8 million people may be in need, with 4.1 million requiring health assistance. The burden of noncommunicable di
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seases and mental health conditions is expected to worsen. At the same time, international financing for Ukraine’s health response has declined, while humanitarian and health needs remain acute, making sustained support in 2026 critical to prevent further deterioration of essential services.
more
The 2026 appeal seeks nearly US$ 1 billion to respond to 36 emergencies worldwide, including 14 Grade 3 emergencies requiring the highest level of organizational response. These emergencies span sudden-onset and protracted humanitarian crises where health needs are critical.
A reference guide for decision-makers that outlines key issues, checklists, and templates to consider when providing or receiving international aid.
