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Safety of artemisinin and non-artemisinin antimalarials in the first trimester of pregnancy

World Health Organisation (WHO) (2024) C_WHO
Malaria in pregnancy is a significant health problem in malaria-endemic areas. It not only causes substantial childhood morbidity and mortality but also increases the risks of adverse events for pregnant women and their developing fetuses. Most of the burden in these areas is due to infection with P... more
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Clinical management and infection prevention and control for mpox: living guideline, May 2025

World Health Organization WHO (2025) C_WHO
This document is for public health specialists, health emergency responders, clinicians, health facility managers, health and care workers and IPC practitioners including but not limited to those working in primary care clinics, sexual health clinics, emergency departments, dental practices, infecti... more
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TB/HIV Coinfection Regional Clinical Manual 2017 Update

Pan American Health Organization PAHO (2018) C_WHO
The purpose of this guide is to provide updated clinical guidance on TB/HIV, with an emphasis on diagnostic aspects—including new techniques—as well as current treatment, while maintaining a public health approach. By compiling and consolidating the latest World Health Organization recommendatio... more
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Community led-monitoring guide for key malaria programs for civil society organisations

Civil Society For Malaria Elimination CS4ME (2022) CC
Community led-monitoring is based on the principle that «Nothing that is done for us should be done without us”. The combination of this principle with evidence shows that community-led monitoring is an important driver of improved service delivery and health outcomes that needs to be re-empha... more
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Malaria surveillance assessment toolkit

World Health Organization WHO (2022) C_WHO
Implementation reference guide. This Malaria Surveillance Assessment Toolkit implementation reference guide is a comprehensive reference document, as well as a step by-step guide. It aligns and adapts available tools into a single set of standardized tools, which can be used to conduct malaria surve... more
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Malaria vaccines

World Health Organization WHO (2022) C_WHO
Preferred product characteristics and clinical development considerations
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Guidelines on lenacapavir for HIV prevention and testing strategies for long-acting injectable pre-exposure prophylaxis
recommended

World Health Organization WHO (2025) C_WHO
Offering additional pre-exposure prophylaxis (PrEP) choices has the potential to increase uptake and effective use of PrEP, and of HIV prevention overall, as it allows people to choose a method that they prefer. In this guideline, WHO recommends an offering long-acting injectable lenacapavir (LEN... more
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Safety and efficacy of long-acting injectable lenacapavir as pre-exposure prophylaxis to reduce the risk of HIV acquisition: a systematic review
recommended

World Health Organization WHO (2025) C_WHO
Guidelines on lenacapavir for HIV prevention and testing strategies for long-acting injectable pre-exposure prophylaxis. Web Annex B
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Prevention of re-establishment of malaria transmission. Global guidance
recommended

World Health Organization WHO (2025) C_WHO
This global guidance was developed to support malaria-free countries and those that are close to malaria elimination to prevent re-establishment. The document outlines key concepts and principles for preventing re-establishment and provides guidance on strategies, interventions, planning and managem... more
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Tuberculosis among populations at high risk and people in vulnerable situations. Policy brief

World Health Organization WHO (2025) CC
This policy brief presents a summary of current evidence on vulnerability to TB and proposes interventions for equitable, person-centred, and human rights-based TB prevention and care. It aligns with WHO policies and guidance on TB prevention and screening, management of TB and comorbidities, access... more
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Risk communication and community engagement readiness and response toolkit: yellow fever

World Health Organisation WHO (2024) C_WHO
This toolkit is a comprehensive set of practical tools and resources designed to support country-level risk communication and community engagement (RCCE) practitioners, decision-makers, and partners to plan and implement readiness and response activities for yellow fever outbreaks. The toolkit conta... more
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Sustaining priority services for HIV, viral hepatitis and sexually transmitted infections in a changing funding landscape - Operational guidance

World Health Organization WHO (2025) C_WHO
This operational guidance provides a structured approach to support countries in sustaining priority services for HIV, viral hepatitis and sexually transmitted infections in the context of reduced external funding. The guidance is intended for national governments, public health programmes, communit... more
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WHO guidelines for clinical management of arboviral diseases: dengue, chikungunya, Zika and yellow fever
recommended

World Health Organization WHO (2025) C_WHO
The new WHO guidelines provide clinical management recommendations for four of the most widespread arboviruses affecting humans: dengue, chikungunya, Zika, and yellow fever. An integrated approach is vital, as these four diseases often present with similar symptoms, especially in the early stages... more
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Access to safe, effective and quality-assured health products and technologies

World Health Organization WHO (2025) C_WHO
Access to safe, effective and quality-assured health products and technologies is crucial for achieving universal health coverage and primary health care goals. The continued growth of the aging population; increasing burden of noncommunicable diseases; growing burden of mental health issues; climat... more
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Community Early Warning Systems (CEWS) Training Toolkit – Field Guide

International Federation of Red Cross IFRC (2014) CC
The Training Toolkit for Community Early Warning Systems is an operational manual that aims to strengthen early warning systems in a developing country context. It accompanies and should put into practice the guiding strategic principles found in the Community Early Warning Systems: Guiding Principl... more
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Target product profiles for tuberculosis screening tests

World Health Organization WHO (2025) C_WHO
Despite being a preventable and curable infectious disease, tuberculosis (TB) has continued to elude global controll efforts. In 2023, 8.2 milion people with TB were diagnosed and notified to the WHO, the hightest number ever reported since WHO began tracking.
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NCDs at a Glance 2025. NCDs surveillance and monitoring: Noncommunicable disease mortality and risk factor prevalence in the Americas

Pan American Health Organization PAHO (2025) C_WHO
Effective surveillance and monitoring of noncommunicable diseases (NCDs) and their risk factors are essential for informing evidence-based public health policies, addressing health inequities, and ensuring progress toward global and regional targets. By tracking trends in NCDs, their modifiable risk... more
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Abortion care guideline, 2nd ed

World Health Organization WHO (2025) C_WHO
The objective of this guideline is to present the complete set of all WHO recommendations and best practice statements relating to abortion. While legal, regulatory, policy and service-delivery contexts may vary from country to country, the recommendations and best practices described in this docume... more
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Issue Brief: Update on TB 2025

The MEDBOX Team (2025) CC
Tuberculosis (TB) remains a significant global health challenge, with an estimated annual death rate of approximately one per 100,000 people in countries with low TB prevalence. Rapid reductions in TB cases and deaths worldwide depend on research breakthroughs, including the development of new vac... more
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Continental Cholera Emergency Preparedness and Response Plan for Africa 1.0
recommended
New

Africa Center for Disease Control and Prevention CDC (2025) CC
This document outlines the plan for a continental cholera prevention and control with the implementation framework for the Cholera IMST, detailing its governance structure, strategic priorities, and operational modalities