This brief report summarizes recent information on HIV drug resistance (HIVDR) in the era of integrase-strand transfer inhibitors (INSTI) for HIV prevention and treatment.
Adolescents and young adults aged 10-24 remain underserved in the global response against HIV. Combination prevention, treatment and care programmes use a mix of evidence-based interventions to meet the current HIV prevention needs of adolescents and young adults. However, there needs to be a focus ...on priority interventions that are evidence-based, practical, contextual and sustainable. This document highlights interventions and recommendations that have passed through the evidence-based lens of the WHO.
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This guideline includes 48 updated and new evidence-based recommendations related to MNS conditions. The guideline is targeted towards non-specialized health workers at primary- or secondary-level healthcare facilities, or those working at the district level including basic inpatient and outpatient ...services.
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The primary audience for this guideline includes policy-makers or service providers who are responsible for developing national and local health-care protocols and policies related to care during pregnancy, childbirth and the postnatal period, and those directly providing care to women during pregna...ncy, including obstetricians, midwives, endocrinologists, nurses, general practitioners, dietitians and diabetes educators, and managers of maternal and child health programmes, in all settings.
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In an era of constrained resources and tightening budgets, strategic prioritization in tuberculosis (TB) programming is more critical than ever. Countries must make informed decisions to allocate limited resources effectively - maximizing impact, preventing avoidable deaths, and sustaining progress ...towards ending TB.
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The ILO has joined forces with Gallup to carry out a groundbreaking global survey covering 50 countries that sheds further light on the causes of the persistence of HIV-related stigma and discrimination in the world of work.
Long-lasting insecticidal nets (LLINs) treated with a pyrethroid insecticide and the synergist piperonyl butoxide (PBO) have become available. Two of these nets (Olyset®Plus and PermaNet®3.0) have a WHO Pesticide Evaluation Scheme (WHOPES) interim recommendation as LLINs
Presentation on PPE and standard precautions
Nota científica
24 de abril de 2020
El desarrollo de inmunidad a un patógeno por infección natural es un proceso de varias etapas que suele producirse a lo largo de una o dos semanas. El organismo responde a una infección vírica de forma inmediata a través de una respuesta innata no específ...ica, en la que los macrófagos, los neutrófilos y las células dendríticas frenan el avance del virus y pueden incluso evitar que este provoque síntomas. A esta respuesta no específica le sigue una respuesta adaptativa en la que el organismo genera anticuerpos que se unen específicamente al virus. Estos anticuerpos son las proteínas denominadas inmunoglobulinas. El organismo también genera linfocitos T que reconocen y eliminan las células infectadas por el virus: es lo que se conoce como inmunidad celular. Esta respuesta adaptativa combinada puede eliminar el virus del organismo y, si la respuesta es suficientemente intensa, puede evitar el agravamiento de la enfermedad o la reinfección por el mismo virus. Este proceso se mide a menudo a través de la presencia de anticuerpos en la sangre.
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Prevención y control de infecciones y nuevo coronavirus (COVID-19): precauciones estándares y uso de equipos de protección personal
Agenda
Visión general de la historia natural del COVID-19
Precauciones estándares
Precauciones adicionales según mecanismos de transmisión
Evaluación de ri...esgo y EPP
Requisitos para uso de EPP
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Document d’information scientifique
24 avril 2020
Le développement d’une immunité face à un agent pathogène à la suite d’une infection naturelle comporte plusieurs étapes et prend généralement une à deux semaines. Une infection virale entraîne immédiatement une réponse immunit...aire innée, non spécifique, au cours de laquelle les macrophages, les neutrophiles et les cellules dendritiques ralentissent la progression du virus et peuvent même éviter l’apparition de symptômes. Cette réponse non spécifique est suivie d’une réponse adaptative, au cours de laquelle l’organisme produit des anticorps qui se lient spécifiquement au virus. Ces anticorps sont des protéines appelées immunoglobulines. L’organisme produit également des lymphocytes T qui reconnaissent et éliminent les cellules infectées par le virus. Cette réponse adaptative permet parfois d’éliminer le virus de l’organisme et, si elle est suffisamment forte, d’éviter l’aggravation de la maladie ou la réinfection par le même virus. Ce processus est souvent mesuré par la présence d’anticorps dans le sang.
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Vitamin A deficiency is a risk factor for blindness and for mortality from measles and diarrhoea in children aged 6–59 months. We aimed to estimate trends in the prevalence of vitamin A defi ciency between 1991 and 2013 and its mortality burden in low-income and middle-income countries.
A patient leaflet for primary care prescribers to hand out to patients: it explains to patients what antibiotic resistance is and why appropriate use of antibiotics is important.
The COVID-19 vaccine tracker and landscape compiles detailed information of each COVID-19 vaccine candidate in development by closely monitoring their progress through the pipeline.
The COVID-19 vaccine tracker:
Provides summary tables of COVID-19 vaccine candidates in both clinical and pre-...clinical development;
Provides analysis and visualization for several COVID-19 vaccine candidate categories;
Tracks the progress of each vaccine from pre-clinical, Phase 1, Phase 2 through to Phase 3 efficacy studies and including Phase 4 registered as interventional studies;
Provides links to published reports on safety, immunogenicity and efficacy data of the vaccine candidates;
Includes information on key attributes of each vaccine candidate and
Allows users to search for COVID-19 vaccines through various criteria such as vaccine platform, schedule of vaccination, route of administration, developer, trial phase and clinical endpoints.
The database is updated regularly - twice a week (Tuesday and Friday, 17:00 CET).
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Os trabalhadores da saúde estão na linha de frente para resposta ao surto de COVID-19, portanto, estão expostos a perigos que os colocam em risco de infecção. Os perigos incluem exposição ao patógeno, longas jornadas de trabalho, estresse emocional, fatiga, síndrome do esgotamento físico e... mental ligado ao trabalho (síndrome de burnout), estigma, e violência física e psicológica. Este documento destaca os direitos e responsabilidades dos trabalhadores da saúde, inclusive as medidas específicas necessárias para proteger a segurança e a saúde ocupacional.
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Orientations provisoires
20 mars 2020
Ce document résume les orientations actuelles de l'OMS pour la surveillance mondiale de la COVID-19 chez l'homme, due à une infection par le nouveau coronavirus 2019. Ces orientations sont à lire en se référant aux orientations de l'OMS sur les activit...és de préparation opérationnelle et de riposte, dans lesquelles l'identification et le dépistage actifs des cas, ainsi que la recherche des contacts sont fortement recommandés dans tous les scénarios de transmission. La notification globale des cas doit être considérée comme une mesure provisoire uniquement lorsque la notification des cas individuels n'est pas possible. L’OMS continuera de mettre à jour ces orientations au fur et à mesure que de nouvelles informations sur la COVID-19 seront disponibles.
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