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Occupational exposures to Ebola virus in Ebola treatment center, Conakry, Guinea

Savini H, Janvier F, Karkowski L, et al. Centers for Disease Control and Prevention (2017) C_CDC

Emerg Infect Dis. 2017 Aug (Accessed July 18,2017) Abstract: We report 77 cases of occupational exposures for 57 healthcare workers at the Ebola Treatment Center in Conakry, Guinea, during the Ebola virus disease outbreak in 2014-2015. Despite the high incidence of 3.5 occupational exposures/healt... more

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Antibiotic resistance: How does antibiotic resistance spread?

European Centre for Disease Prevention and Control (2014) C2

Antibiotic resistance is a natural occurrence caused by mutations in bacteria’s genes. However, inappropriate use of antibiotics accelerates the emergence and spread of antibiotic-resistant bacteria. When exposed to antibiotics, susceptible bacteria are killed; while excessive antibiotic use or th... more

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Guidelines for Handling Decedents Contaminated with Radioactive Materials

Wood MC, DePaolo, F, Whitaker RD Centers for Disease Control and Prevention (CDC) (2007) C_CDC

Detonation of a nuclear weapon or activation of a radiological dispersal device could cause radioactively contaminated decedents. These guidelines are designed to address both of these scenarios. They could also be applicable in other instances where decedents’ bodies are contaminated with radioa... more

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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Monitoring and Evaluation of COVID-19 Rapid Antigen Diagnostic Test Rollout in Africa
recommended

African Union; Africa CDC Centres for Disease Control and Prevention (2021) C1

Limited coverage of laboratory services and long turnaround times from real-time reverse transcription-polymerase chain reaction (rRT-PCR) for the detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has been insufficient to meet the demands in many African countries in response... more

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CDC Afrique protocole par la surveillance renforcée du syndrome respiratoire aigu sévère (SRAS) et du syndrome grippal pour COVID-19 en Afrique

Centre Africain de contrôle et de prévention des maladies (CDC Afrique); Union Africaine (2020) C_CDC

Centre Africain de contrôle et de prévention des maladies (CDC Afrique) protocole par la surveillance renforcée du syndrome respiratoire aigu sévère (SRAS) et du syndrome grippal pour COVID-19 en Afrique Mars 2020 Le nombre d’États membres de l’Union signalant des cas de COVID-19 est ... more

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Non-communicable diseases, injuries, and mental ill-health in Africa: the role of the Africa CDC

Africa Center for Disease Control and Prevention CDC (2022) C_CDC

The Africa Centres for Disease Control and Prevention (Africa CDC) was established in 2017, after the west Africa Ebola virus disease outbreak. Upon creation, the role of Africa CDC was to mandate strengthening of the capacity of public health institutions in Africa to prevent, detect, and respond ... more

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African Union AMR Landmark Report: Voicing African Priorities on the Active Pandemic

Africa Center for Disease Control and Prevention (2024) CC

Antimicrobial resistance (AMR) has emerged as a leading cause of death in the African region, surpassing fatalities from malaria, HIV, and TB. In response to this critical threat, the region has adopted the AMR Global Action Plan and the African Union Framework for Antimicrobial Resistance Control 2...020 – 2025, which is tailored to meet the specific needs of African nations through a coordinated approach. While most countries in the region have developed and prioritized National Action Plans (NAPs) to tackle AMR, the overall response remains inadequate given the magnitude of the threat, which endangers human, animal, environmental, aquatic, and plant health. Africa bears a significant burden of infectious diseases, accounting for approximately 95% of malaria deaths, 70% of people living with HIV, and 25% of TB deaths globally. In 2019, AMR was linked to approximately 55,000 deaths from HIV, 30,000 from malaria, and 255,000 overall. Major drivers of AMR in the region include the overuse and misuse of antimicrobials in human and food systems, migration, suboptimal vaccination rates, and environmental contamination from hospital and pharmaceutical effluents. Additionally, there is a lack of access to quality-assured antimicrobials and diagnostics, compounded by inadequate knowledge about AMR. Unlike high-income countries, where indiscriminate antimicrobial use is the primary factor driving AMR, African countries face additional challenges, including a lack of access to clean and safe water, poor Water, Sanitation, and Hygiene (WASH) programs, inadequate infection prevention measures, and suboptimal vaccinations for preventable diseases. One in three hospitals in the region lacks clean, safe running water, and one in eight people defecate openly due to inadequate sanitation. Investments in WASH, infection prevention, and biosecurity could save approximately 700,000 lives annually. Addressing AMR in Africa requires a comprehensive, multi-sectoral approach involving the entire society. Sustainable access to antimicrobials, including antibiotics, vaccines, and therapeutics, is crucial, as lack of access leads to more morbidity and mortality than AMR itself. Support for the region should focus on preventing infections, strengthening health and food systems, developing human resources, ensuring sustainable access to diagnostics and therapeutics, and investing in laboratory infrastructure to support surveillance and data generation. more

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A Review of Community Health Worker (CHW) knowledge, attitudes and practices relating to the sexual health of MSM, including existing training materials and manuals in Europe & neighbouring countries

C. Folch; P. Fernández-Dávila; J. Palacio-Vieira; et al. European Commission; Centre d'Estudis Epidemiològics sobre les Infeccions de Transmissió Sexual i Sida de Catalunya (CEEISCAT); European AIDS Treatment Group (2020) C2

Accessed: 07.03.2020 A Review of Community Health Worker (CHW) knowledge, attitudes and practices relating to the sexual health of MSM, including existing training materials and manuals in Europe and neighbouring countries (D5.1) Contract 2015 71 01 A behavioural survey for HIV/AIDS and assoc... more

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Guidance on Setting Up an Isolation Ward for COVID-19 Cases (Arabic Version)
recommended

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C1

إرشاداتٌ حول إنشاء عنابر العزل الخاصة بالحالات المصابة بفيروس كورونا المستجد This document simplifies the WHO guidance on severe acute respiratory infection (SARI) treatment centres and is meant to be accessible to healthcare work... more

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Action Protocol for Enhanced SARI and ILI Surveillance for COVID-19 in Africa (Arabic)

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C2

March 2020 The number of African Union Member States reporting COVID- 19 cases is increasing and there is a likelihood of community transmission. The WHO recently modified the COVID-19 suspect case definition to include severe acute respiratory infection and advises testing of all severe acute r... more

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Action Protocol for Enhanced SARI and ILI Surveillance for COVID-19 in Africa

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C2

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Interim guidance on COVID-19 Rapid Antigen self-testing to African Union Member States

African Union; Africa CDC Centres for Disease Control and Prevention (2022) C1

This guidance addresses rationale, risk-based scenarios, practical considerations prior to adoption of the self-testing products, quality assurance, safety and ethical considerations, and data management considerations for COVID-19 self-testing. The Africa CDC recommends the use of rapid antigen sel... more

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West Africa - Ebola Outbreak, Fact Sheet #39, Fiscal Year (FY) 2015 (as of July 14, 2015)

US Agency for International Development, Centers for Disease Control and Prevention (2015)

The Government of Liberia (GoL) reports three additional EVD cases linked to the Margibi County cluster, including one in Liberia’s Montserrado County; new confirmed case total reaches six Recently extended Operation Northern Push strengthens contact tracing and EVD prevention activities ... more

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Covid-19 Test to Treat Guidelines
recommended

African Union; Africa CDC Centres for Disease Control and Prevention (2022) C1

n response to the outbreak, the Africa Centres for Disease Control and Prevention (Africa CDC) has been supporting African Union Member States in responding to the COVID-19 pandemic through a variety of interventions such as non-pharmaceutical interventions, quarantine, testing, isolation, contact t... more

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Core components for IPC - Implementation tools and resources

World Health Organization WHO (2020) C_WHO

Based on scientific evidence, expert consensus and country experiences, the WHO core components for infection prevention and control (IPC) are the foundation for establishing or strengthening effective programmes at the national and facility level. These new guidelines on core components of infecti... more

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Achieving quality health services for all, through better water, sanitation and hygiene

World Health Organization WHO (2020) C_WHO

Lessons from three African Countries. Achieving Health for All, and in particular universal health coverage (UHC), will not happen without fully functioning basic water, sanitation and hygiene (WASH) services in all health care facilities. Such services are needed to provide quality care, ensure ad... more

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Decontamination and reprocessing of medical devices for health care facilities: aide-memoire

World Health Organization WHO (2022) CC

Decontamination of medical devices plays an important role in the prevention of health care-associated infections. It includes cleaning, disinfection and/or sterilization. The processes involved in decontamination are complex, require specific infrastructure and equipment, and involve several sequen... more

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Note d’orientation : maintien des mesures de lutte anti-infectieuse contre la COVID-19 dans les établissements de santé, 14 septembre 2022

Organisation Mondiale de la Santé OMS (2022) C_WHO

Note d'orientation 7 juin 2022. Ce document a pour but d'encourager les pays à élaborer et à mettre en œuvre des politiques visant à maintenir et à renforcer les programmes et mesures de prévention des infections dans les établissements de soins de santé dans le contexte de la transmission... more

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Overview of technologies for the treatment of infectious and sharp waste from health care facilities (Arabic Version)

World Health Organization WHO (2022) C_WHO

نظرة عامّة على التقنيّات المستخدمة لمعالجة النفايات المُعدِية والحادّة الناتجة عن مرافق الرعاية الصحيّة This document provides an overview of specific health care waste technologies for the treatment of solid ... more

Monitoring and Evaluation of COVID-19 Rapid Antigen Diagnostic Test Rollout in Africa recommended

Guidance on Setting Up an Isolation Ward for COVID-19 Cases (Arabic Version) recommended

Covid-19 Test to Treat Guidelines recommended

Monitoring and Evaluation of COVID-19 Rapid Antigen Diagnostic Test Rollout in Africa
recommended

Guidance on Setting Up an Isolation Ward for COVID-19 Cases (Arabic Version)
recommended

Covid-19 Test to Treat Guidelines
recommended