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EPI 1: Antiepileptic medications for management of acute convulsive seizures when no intravenous access is available

World Health Organization WHO (2015) C_WHO

[Updated 2015] Scoping Question: In adults with acute convulsive seizures in first-level care or in the community (when no IV access is available), which antiepileptic medications produce benefits and/or harm when compared to comparator?

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Eradication of yaws: a guide for programme managers

World Health Organization WHO (2018) C_WHO

This document provides guidance for countries on how to implement activities to achieve the interruption of yaws transmission. It is intended for use by national yaws eradication programmes, partners involved in the implementation of yaws eradication activities and WHO technical staff who provide te... more

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Therapeutics and COVID-19 (Living Guideline, 10 November 2023)

World Health Organization WHO (2023) C_WHO

WHO has updated its guidelines for COVID-19 therapeutics, with revised recommendations for patients with non-severe COVID-19. This is the 13th update to these guidelines. Updated risk rates for hospital admission in patients with non-severe COVID-19 The guidance includes updated risk rates for... hospital admission in patients with non-severe COVID-19. The current COVID-19 virus variants tend to cause less severe disease while immunity levels are higher due to vaccination, leading to lower risks of severe illness and death for most patients. This update includes new baseline risk estimates for hospital admission in patients with non-severe COVID-19. The new ‘moderate risk’ category now includes people previously considered to be high risk including older people and/or those with chronic conditions, disabilities, and comorbidities of chronic disease. The updated risk estimates will assist healthcare professionals to identify individuals at high, moderate or low risk of hospital admission, and to tailor treatment according to WHO guidelines: **High: **People who are immunosuppressed remain at higher risk if they contract COVID-19, with an estimated hospitalization rate of 6%. **Moderate: **People over 65 years old, those with conditions like obesity, diabetes and/or chronic conditions including chronic obstructive pulmonary disease, kidney or liver disease, cancer, people with disabilities and those with comorbidities of chronic disease are at moderate risk, with an estimated hospitalization rate of 3%. Low: Those who are not in the high or moderate risk categories are at low risk of hospitalization (0.5%). Most people are low risk. Review of COVID-19 treatments for people with non-severe COVID-19 WHO continues to strongly recommend nirmatrelvir-ritonavir (also known by its brand name ‘Paxlovid’) for people at high-risk and moderate risk of hospitalization. The recommendations state that nirmatrelvir-ritonavir is considered the best choice for most eligible patients, given its therapeutic benefits, ease of administration and fewer concerns about potential harms. Nirmatrelvir-ritonavir was first recommended by WHO in April 2022. If nirmatrelvir-ritonavir is not available to patients at high-risk of hospitalization, WHO suggests the use of molnupiravir or remdesivir instead. WHO suggests against the use of molnupiravir and remdesivir for patients at moderate risk, judging the potential harms to outweigh the limited benefits in patients at moderate risk of hospital admission. For people at low risk of hospitalization, WHO does not recommend any antiviral therapy. Symptoms like fever and pain can continue to be managed with analgesics like paracetamol. WHO also recommends against use of a new antiviral (VV116) for patients, except in clinical trials. The update also includes a strong recommendation against the use of ivermectin for patients with non-severe COVID-19. WHO continues to advise that in patients with severe or critical COVID-19, ivermectin should only be used in clinical trials. more

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Problem Management Plus (PM+)
recommended

World Health Organization WHO (2016) C_WHO

Individual psychological help for adults impaired by distress in communities exposed to adversity. The manual describes a scalable psychological intervention called Problem Management Plus (PM+) for adults impaired by distress in communities who are exposed to adversity. Aspects of Cognitive Behavi... more

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Disaster Recovery Guidance Series - Communication during Disaster Recovery

World Bank, GFDRR (2019) C1

This Guide provides practical guidance for governments regarding how to effectively communicate with communities during the recovery phase following an emergency. It explains how to identify communication needs, and presents “best fit” communication methods and strategies to deploy to support Di... more

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Clinical management of COVID-19: living guideline, 13 January 2023

World Health Organisation (WHO) (2023) C_WHO

As of 12 December 2022, over 645 million people worldwide have been diagnosed with COVID-19, with over 6.6 million deaths (4). The Omicron variant, which emerged in late November 2021, and its subvariants, are now the dominant circulating viruses, contributing to the ongoing surge in several countr... more

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Suicide first aid guidelines for India

MHFA MHFA (2009) CC

How to use these Guidelines These guidelines are a general set of recommendations about how you can help someone who may be at risk of suicide. Each individual is unique and it is important to tailor your support to that person’s needs. These recommendations therefore may not be appropriate for... more

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Impact of COVID-19 on Gender Equality and Women’s Empowerment in East and Southern Africa

UN Women, UNFPA (2021) CC

abridged version, March 2021 he study highlights the impacts of COVID-19 on women and men as gleaned from research conducted during 2020, as well as the Computer Assisted Telephonic Interviews (CATI) Rapid Gender Assessments (RGAs) executed by UN Women, UNFPA and partners in seven countries in the ... more

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Achieving quality universal health coverage through better water, sanitation and hygiene services in health care facilities: A focus on Ethiopia

World Health Organization (WHO) (2017) C_WHO

A two-week mission was conducted by WASH and quality UHC technical experts from WHO headquarters and supported by the WHO Ethiopia Country Office (WASH and health systems teams) in July 2016, to understand how change in WASH services and quality improvements have been implemented in Ethiopia at nati... more

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Operational manual on indoor residual spraying: Control of vectors of malaria, Aedes-borne diseases, Chagas disease, leishmaniases and lymphatic filariasis
recommended

World Health Organization WHO (2024) C_WHO

Indoor residual spraying (IRS) involves applying residual insecticide to potential vector resting sites on the interior surfaces of human dwellings or other buildings. The main aim of IRS is to kill vectors before they are able to transmit pathogens to humans. When carried out correctly, IRS has his... more

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Young people as advocates - Your action for change toolkit

IPPF (International Planned Parenthood Federation) (2011) C2

From choice, a world of possibilities Want to change the world? Here's how... "i asked: 'Why doesn't somebody do something?' Then I realized I was somebody"

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Infection prevention and control guideline for Ebola and Marburg disease, August 2023
recommended

World Health Organization WHO (2023) CC

Ebola disease and Marburg disease outbreaks continue to occur in Africa, with increased frequency. In addition to resulting in high mortality and morbidity, the outbreaks generate fear and mistrust about the response activities within the communities affected. Infection prevention and control (IP... more

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Republic of Congo: Population Movement - Emergency Plan of Action (EPoA) MDRCG016

International Federation of Red Cross And Red Crescent Societies IFRC (2019) C1

On Sunday 16th December 2018, some villages in the Province of Mai-Nambiar, Democratic Republic of Congo, neighboring the district of Makotimpoko in the Republic of Congo (CongoBrazzaville) were affected by inter-ethnic conflict between the Banunu and the Batende. The fighting has resulted in 400 fa... more

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COVID-19 Exercise Programme - Drills for Vaccine Deployment

WHO (2022) C_WHO

This drill package is part of a broader COVID-19 simulation exercise package, including vaccine tabletop exercises(TTX). For exercises to be most effective, it is recommended they should be part of a comprehensive programme made up of progressively complex exercises, each exercise ... more

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Research and Evaluation Agenda for HIV and Maternal Health in sub-Saharan Africa

Kendall, Tamil; Danel, Isabella (2014) C1

Women and Health Initiative Working Paper No. 1. Women and Health Initiative
Improving maternal health in the context of the sub-Saharan African HIV epidemic requires greater understanding of the relationships between HIV disease and maternal morbidity and mortality, integrated and effective resp... more

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Ukrainian Crisis - Situational Analysis 18 Nov 2022

Data Friendly Space Reliefweb OCHA Services (2022) C2

Conflict In early October, Ukrainian forces continued recapturing areas of southern and eastern oblasts, notably Lyman (Donetsk oblast). The liberation of thousands of square kilometres resulted in the grim discovery of two new mass graves in Lyman and Sviatohirsk (containing of 120 civilian bodi... more

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Operational Guidance Mental Health & Psychosocial Support Programming for Refugee Operations

UN High Commissioner for Refugees UNHCR (2013) C1

This operational guidance on MHPSS provides a practical orientation and tools for UNHCR country operations. It covers specific points of good practice to consider when developing MHPSS programming and offers advice on priority issues and practical difficulties, while also providing some background i... more

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Applying humanitarian standards to fight COVID-19

Sphere (2021) C_Sphere

Updated 8 June 2021. Coronavirus is spreading globally. How can individuals, communities, humanitarian actors, local and national authorities best respond to uphold the rights of all affected people?

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Role of Information Sources in Vaccination Uptake: Insights From a Cross-Sectional Household Survey in Sierra Leone, 2019

Kulkarni, S.; et al. (2022) C1

Global Health Science and Practice February 2022, https://doi.org/10.9745/GHSP-D-21-00237 Key Findings: Exposure to vaccination information from faith leaders and health facilities was associated with increased likelihood of vaccination uptake. The significant association between exposure to a... more

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Publication of selected legal provisions in domestic and international laws on physical accessibility

Uganda National Action on Physical Disability (UNAPD) (2010)

Accessibility is by law; not just a favour. The booklet contains what the laws say about physical accessibility and their interpretation

Problem Management Plus (PM+) recommended

Operational manual on indoor residual spraying: Control of vectors of malaria, Aedes-borne diseases, Chagas disease, leishmaniases and lymphatic filariasis recommended

Infection prevention and control guideline for Ebola and Marburg disease, August 2023 recommended

Problem Management Plus (PM+)
recommended

Operational manual on indoor residual spraying: Control of vectors of malaria, Aedes-borne diseases, Chagas disease, leishmaniases and lymphatic filariasis
recommended

Infection prevention and control guideline for Ebola and Marburg disease, August 2023
recommended