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There is widespread recognition of the growing threat of infectious disease epidemics and pandemics spreading across countries or continents—especially following the recent Ebola and COVID-19 pandemics. Vulnerable groups (including children, older adults, ethnic minorities and other at-risk group
...
s) have disproportionately borne the brunt of significant health, social, and economic effects of these epidemics and pandemics, with varying degrees of support received depending on the context. While many argue that communities should or need to play a critical role in supporting and leading preparedness and response efforts, work still needs to be done to engage them effectively. In many instances, modes of engagement with communities—especially by state authorities–have come too late, often as an afterthought are not adequately thought through and have undermined public trust in and support for, disease prevention and control measures
more
The West African Ebola virus disease (EVD) outbreak in 2014 emerged in a region in Africa that had previously not reported any EVD outbreak. Subsequently, the outbreak rapidly spread and was protracted in the three Mano River basin countries (Guinea, Sierra Leone and Liberia), with spillover cases i
...
n Nigeria, Senegal and Mali and, for the first time, importation into Europe and the USA. It became the most extensive and protracted EVD outbreak in history, followed by the 2018 outbreak in the Democratic Republic of the Congo (DRC). For the first time, cases were reported in urban centers, underscoring the urban spread of the disease. Its devastation had a far-reaching impact on lives in the three largely affected countries for years to follow. A total of 28,616 cases and 11,310 deaths were reported from Guinea, Sierra Leone and Liberia, with an additional 36 cases reported from Italy, Mali, Nigeria, Senegal, Spain, the UK and the USA.
more
HIV Treatment Adherence Counseling and Retention Guide
Anderson, L.; J. Jospin, S. Safren, et al.
ICAP Columbia University, and Centers for Disease Control and Prevention CDC
(2024)
C_CDC
A job aid for cadres supporting adolescents living with HIV (ages 15-19) in Orphans and Vulnerable
Children (OVC) Programs
Int. J. Environ. Res. Public Health 2021, 18(5), 2477; https://doi.org/10.3390/ijerph18052477
Topics in Antiviral Medicine, March 4, 2025
The Lancet HIV. Volume 12, Issue 10e712-e721October 2025. This article from The Lancet HIV estimates the impact of the PEPFAR funding pause for PrEP on HIV infections in sub-Saharan Africa.
Progress on the sustainable development goals.
Since 2008, the HIV and AIDS Data Hub has been providing decision-makers and experts high quality, accessible and up-to-date data on HIV in Asia and the Pacific. Working with many regional and national partners, we compile, update and analyse evidence on the HIV epidemic in Asia and the Pacific. In
...
this region, HIV is clustered and concentrated among specific sub-populations, as well as within certain geographical areas in countries, hence the Data Hub prominently profiles subnational and key populations at higher risk data. Effective policies and interventions require the best available evidence, which is what the Data Hub aims to provide in one convenient web site.
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This document is itended as a quick guide of healtcare workers involved in clincial management
Nature Sci Rep 15, 35329 (2025). https://doi.org/10.1038/s41598-025-19261-7
Front Psychiatry. 2022 Aug 11;13:937723. doi: 10.3389/fpsyt.2022.937723. PMID: 36061286; PMCID: PMC9429610. The review findings show that there exist several diverse interventions that promote mental health among adolescents in sub-Saharan Africa. These interventions can be implemented in diverse se
...
ttings including schools, communities, health facilities, and camps, and can be delivered by lay persons.
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These messages may be used as stand-alone resources, and also could be used as a supplement to The Essential Package, a comprehensive set of tools and guides for program managers and service providers supporting programs that address the unique needs and competencies of vulnerable children in a holi
...
stic way.
more
A job aid for cadres supporting caregivers of children and adolescents living with HIV (ages 0-14) in Orphans and Vulnerable Children (OVC) Programs
A Training Manual for Para-Social Workers. A Project of the Social Work HIV/AIDS
Partnership for Orphans Vulnerable Children in Tanzania. This training presentation is continually being evaluated and updated to
reflectcurrent needs and best practices. It should be viewed as work in progress
J Int AIDS Soc. 2022 Nov;25(11):e25970. doi: 10.1002/jia2.25970. PMID: 36377082; PMCID: PMC9663860. These reassuring findings suggest that dolutegravir and raltegravir are effective and safe as preferred regimens in children and adolescents living with HIV. With the rollout of dolutegravir in paedia
...
tric populations already underway, it is critical that data are collected on safety and effectiveness in infants, children and adolescents, including on longer-term outcomes, such as weight and metabolic changes.
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J Int AIDS Soc. 2025 Jun;28(6):e26526. doi: 10.1002/jia2.26526. PMID: 40515449; PMCID: PMC12166130.
JAMA. 2025;333(7):609–628. doi:10.1001/jama.2024.24543
Lancet HIV 2019 Published Online March 15, 2019 http://dx.doi.org/10.1016/S2352-3018(19)30052-9
Analytical antiretroviral treatment interruption (ATI) is an important feature of HIV research, seeking to achieve
sustained viral suppression in the absence of antiretroviral therapy (ART) when the goa
...
l is to measure effects of
novel therapeutic interventions on time to viral load rebound or altered viral setpoint. Trials with ATIs also intend
to determine host, virological, and immunological markers that are predictive of sustained viral control off ART.
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A Flipchart for Child an Adolescent Disclosure Counseling (CADC) SOP3
Levin, L.; M. Vujovic, and J. Turner
Ministry of Health, South Africa; PEPFAR; USAID; Right to Care; et al.
(2024)
C1
Right to Care mini flipster
Journal of the International AIDS Society 2024, 27:e26233.
Most adult ART clients in South Africa were satisfied with their care, but those enrolled in DSD models expressed slightly greater satisfaction than those remaining in conventional care. Efforts should focus on enrolling more eligible patie
...
nts into DSD models, expanding eligibility criteria to cover a wider client base, and further improving the models’ desirable characteristics.
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