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Publication Years
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2
Monkeypox virus is an orthopoxvirus that causes human monkeypox, a viral disease with symptoms similar to smallpox, including fever and rash. Following the worldwide eradication of smallpox in 1980, monkeypox emerged as the most significant orthopoxvirus infection in humans. Cases are most often rep
...
orted from rural areas of Central and West African countries, particularly in regions close to tropical rainforest where people may have contact with infected animals. Someone can become infected through direct contact with respiratory droplets of another person who has monkeypox in the home or in a health facility, or with contaminated materials such as bedding. Although these are the main modes of person-to-person transmission, monkeypox outbreaks tend to occur in small clusters of a few cases without leading to widespread community transmission. For this reason, outbreaks can be easily controlled when responded to rapidly. On several occasions, monkeypox has been reported in other regions due to importation by travelers or infected animals. This course provides a general introduction to the disease through a video and accompanying downloadable presentation that can be reviewed at your own pace. It is intended for health personnel responsible for prevention and control of monkeypox, and for the general public.
The content and scope of this course on monkeypox have been tailored for outbreaks in African countries where the disease is endemic. The course material was last updated in 2020 and may not reflect most recent WHO guidance issued for the multi-country outbreak in 2022.
more
La variole du singe est une maladie infectieuse émergente causée par un virus transmis par des animaux infectés, le plus souvent des rongeurs. Elle peut ensuite se propager d’une personne à l’autre, mais la transmission de personne à personne ne peut à elle seule entretenir une éclosion.
...
La présentation clinique est semblable à celle observée chez les patients atteints autrefois de la variole, mais moins grave. La variole a été éradiquée dans le monde entier en 1980. Cependant, la variole du singe est encore présente sporadiquement dans des régions d'Afrique centrale et occidentale, près des forêts tropicales humides. De manière générale, le taux de létalité dans les épidémies de variole du singe est de 1 à 10 %, mais avec des soins appropriés, la plupart des patients se rétablissent.
more
Monkeypox is a viral zoonotic disease, caused by monkeypox virus, recognized as the most important orthopoxvirus infection after the eradication of smallpox.
This course offers public health officers and
...
health workers in-depth information to understand the epidemiology, modes of transmission, clinical presentation, diagnostics, and treatment of monkeypox, as well as the strategies needed for effective prevention and outbreak investigation and response.
more
L’orthopoxvirose simienne, aussi connu sous les noms de variole du singe ou monkeypox, est une zoonose causée par l'orthopoxvirus simien et reconnue comme l'infection à orthopoxvirus la plus importante depuis l'éradication de la variole.
Ce cours offre aux personnel de santé publique et aux a
...
gents de santé des informations approfondies pour comprendre l'épidémiologie, les modes de transmission, la présentation clinique, le diagnostic et le traitement de la variole du singe, ainsi que les stratégies nécessaires pour la prévention, Ce cours offer aussi des suggestions pour mener une enquête et mettre en oeuvre une réponse efficace à une flambée de variole du singe.
more
27 June 2022
During the COVID-19 health crisis, community pharmacists had an enhanced role in supporting health-care systems that were overburdened by managing seriously ill patients. This study was undertaken t
...
o determine the patterns of community supply of antiviral and antibacterial agents from community pharmacies during the COVID-19 pandemic in selected countries in eastern Europe and central Asia. Nine countries – Armenia, Georgia, Kazakhstan, Kyrgyzstan, North Macedonia, the Russian Federation, Serbia, Tajikistan and Uzbekistan – participated in this cross-sectional study.
more
The goal of the global outbreak response for monkeypox is to stop human-to-human transmission of monkeypox, with a priority focus on communities at high risk of exposure which may differ according to context, and to effectively use strong public health
...
measures to prevent onward spread of the disease. Judicious use of vaccines can support this response. This interim guidance, developed with the advice and support of the Strategic Advisory Group of Experts (SAGE) Working Group on smallpox and monkeypox vaccines, provides the first WHO recommendations on vaccines and immunization for monkeypox. Key points follow.
more
Interim rapid response guidance, 10 June 2022.
It includes considerations for certain populations such as patients with mild disease with considerations for community care, patients with moderate to severe disease, sexually active persons, pregnant or breastfeeding women, children and young persons
...
. The guidance also addresses considerations for clinical management such as the use of therapeutics, nutritional support, mental health services, and post-infection follow-up.
The document provides guidance for clinicians, health facility managers, health workers and infection prevention and control practitioners including but not limited to those working in primary care clinics, sexual health clinics, emergency departments, infectious diseases clinics, genitourinary clinics, dermatology clinics, maternity services, paediatrics, obstetrics and gynaecology and acute care facilities that provide care for patients with suspected or confirmed monkeypox
more
Childhood cancer is curable for the vast majority of children when essential diagnostic, therapeutic and supportive care services are accessible. However, profound inequalities in outcomes exist within and between countries with as few as 20% or 30% of children living in low- and middle-income count
...
ries surviving.
The Global Initiative for Childhood Cancer Overview document presents the CureAll approach to support governments, partners and communities achieve the best possible cancer care for all children. This approach, summarized as four pillars of action supported by three enablers, will improve the care for children with cancer around the world.
more
19 August 2022. A monkeypox case investigation form (CIF) has been designed as a tool for Member States and researchers to conduct in-depth epidemiological investigation of suspected, probable and confirmed cases of monkeypox. This form allows to collect data prospectively or retrospectively for bot
...
h cases and their contacts. The full form is meant to serve as a tool for in-country use and the data are not required to be reported to WHO.
more
Standard precautions aim to protect both health workers and patients by reducing the risk of transmission of microorganisms from both recognized and unrecognized sources. They are the minimum standard of infection prevention and control practices th
...
at should be used by all health-care workers, during the care of all patients, at all times, in all settings. When applied consistently, standard precautions can prevent the transmission of microorganisms between patients, health workers and the environment. This aide-memoire presents a concise overview of important advice for implementation and key elements at a glance.
more
Transmission-based precautions for the prevention and control of infections: aide-memoire
recommended
Transmission-based precautions (TBP) are used in addition to standard precautions for patients with known or suspected infection or colonization with transmissible and/or epidemiologically significant pathogens. The type of TBP assigned to a patient depends on the transmission route of the microorga
...
nism: contact, droplet, or airborne. The following aide-memoire provides important advice for implementation and key elements on TBP in health care.
more
Severe bacterial infections are a leading cause of morbidity and mortality among people with advanced HIV disease, after tuberculosis and cryptococcal disease. For countries to reach the end-AIDS targets for 2030, there is a need to establish a roadmap for managing severe bacterial infections and re
...
duce mortality. The purpose of the meeting was to
Review the current research and implementation data on the use of prophylactic antibiotics (specifically azithromycin/macrolides) as part of the AHD package of care; To review options for preventing SBIs that are in line with goals of reducing AMR; Present the current evidence on diagnostics for SBI; Discuss research gaps and implementation challenges.
more
Multiple countries are reporting severe acute cases of hepatitis of unknown aetiology in children, in several
regions of the world. WHO has developed this clinical case report form (CRF) to support
...
and facilitate reporting
of anonymized, patient-level data of acute hepatitis of unknown aetiology.
more
This document provides interim guidance to countries on testing considerations and strategies for suspect cases of severe acute hepatitis of unknown aetiology in children. It is primarily intended for clinical, programmatic, laboratory and diagnostic stakeholders across Member States and national pu
...
blic health authorities involved in the identification and investigation of cases of severe acute hepatitis in children.
This document is part of a package of guidance for this event, which includes suggested minimum reporting variables and a clinical Case Report Form support Member States with case investigation and reporting.
more
The Interim Guidance for Risk Communication and Community Engagement (RCCE) outlines recommendations, considerations and methods to raise awareness, manage risk perception, maintain trust and proactively support people at risk to make informed decisions to protect themselves and others from monkeypo
...
x. The guidance includes recommendations on identifying and communicating with affected populations and key audiences and avoiding stigma in communications outreach. It also includes key messages about symptoms of monkeypox, transmission, prevention measures, and communicating about uncertainty. This document also provides RCCE guidance for managers and planners of gatherings and events, where close physical contact may create an environment conducive for the transmission of monkeypox. Additionally, this document includes a compendium of recommendations for RCCE methods and resources to support the monkeypox response.
more
Updated recommendations on treatment of adolescents and children with chronic HCV infection
recommended
The new treatment recommendations that extend the 2018 treat all recommendation for adults with chronic HCV infection to include adolescents and children down to 3 years, and to align the existing recommended pangenotypic direct-acting antiviral (DAA) regimens (SOF/DCV, SOF/VEL and G/P) for adults,
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to those for adolescents and children. This alignment is expected to simplify procurement, promote access to treatment among children in low- and middle-income countries and contribute to global efforts to eliminate the disease
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