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DPDx - Laboratory Identification of Parasites of Public Health Concern
Trypanosoma cruzi, is a parasitic protozoan that is the causative agent of Chagas disease (American trypanosomiasis). Currently, six distinct lineages of T. cruzi are classified into discrete typing units (TcI-VI), which vary in
...
their geographic occurrence, host specificity, and pathogenicity.
more
Chagas disease (CD), caused by the parasite Trypanosoma cruzi, affects ~6–7 million people worldwide. Significant limitations still exist in our understanding of CD. Harnessing individual participant data (IPD) from studies could support more in-depth analyses to address
the many outstanding rese
...
arch questions. This systematic review aims to describe the characteristics and treatment practices of clinical studies in CD and assess the breadth and
availability of research data for the potential establishment of a data-sharing platform.
more
Багато людей, яким доводиться тікати від жахливої війни в Україні, приїжджають також до Німеччини. В чужій країні неодмінно виникає безліч питань, особливо щодо ас
...
ектів перебування, медичного забезпечення та соціальної інтеграції. У десяти відео ми даємо відповіді на найважливіші питання для біженців з України і беремо до уваги такі аспекти: життя з ВІЛ та/або туберкульозом, права представників ґендерних меншин, вживання наркотиків і замісна підтримувальна терапія, також робота у сфері інтим-послуг та біженство без українського паспорта.
more
Zugang zum Gesundheitssystem für Unionsbürgerinnen und Unionsbürger, Angehörige des EWR und der Schweiz
Frings, D.
Die Beauftragte der Bundesregierung für Migration, Flüchtlinge und Integration; Die Beauftragte der Bundesregierung für Antirassismus; Gleichbehandlungsstelle EU-Arbeitnehmer
(2021)
C2
In der Europäischen Union (EU) leben über 500 Millionen Menschen. Die Sicherstellung der Gesundheits- versorgung für diese Menschen entspricht einem der wichtigsten sozialen Grund- und Menschenrechte. Auf
die Gewährleistung haben sich die Staaten Europas in der Europäischen Sozialcharta des Eu
...
roparats und die Mitgliedstaaten der EU in der Grundrechtecharta der EU verpflichtet.
more
DNDi’s long-term goal for sleeping sickness, also known as human African trypanosomiasis (HAT), is to develop and register two new drugs that are effective against both Stage 1 and Stage 2 of the disease and both subspecies of the parasite, T.b. gambiense and T.b. rhodesiense. T.b. rhodesiense is
...
an acute form of the disease, occurring primarily in Eastern and Southern Africa. Better treatments for T.b. rhodesiense sleeping sickness are urgently needed.
more
The American Jornal of Tropical Medicine and Hygiene, vol. 105, no.6, pp.1772-1781.
Schistosomiasis, which is the second most important parasitic infection after malaria in terms of its socioeconomic impact, is responsible for the loss of an estimated 4.5 million disability-adjusted life years (DA
...
LYs) worldwide. Schistosomiasis, including both intestinal and urinary forms of the disease, occurs in 78 countries across the globe. An estimated 240 million people are infected, with more than 779 million living at risk globally. The majority of those infected and those at risk for infection live in low-income countries, and approximately 80% of the morbidity occurs in impoverished communities and households in sub-Saharan Africa. Within Uganda, 91 of the 134 districts are endemic for intestinal schistosomiasis caused by Schistosoma mansoni, and the eastern region, especially along Lake Victoria, has one of the highest S. mansoni burdens worldwide. Schistosoma haematobium is only endemic in the five districts of the Lango region in northern Uganda.
more
Bug bites are irritating, and some can be harmful. Learn to identify the type of bug bite and when to seek emergency medical care.
Schistosomiasis, also known as bilharzia, is an infection caused by a parasitic worm that lives in fresh water in subtropical and tropical regions.
Schistosomiasis is a helminthic infection and one of the neglected tropical diseases (NTDs). It is caused by blood flukes of the genus Schistosoma. It is an important public health problem, particularly in poverty-stricken areas, especially those within the tropics and subtropics. It is estimated th
...
at at least 236 million people worldwide are infected, 90% of them in sub-Saharan Africa, and that this disease causes approximately 300,000 deaths annually. The clinical manifestations are varied and affect practically all organs. There are substantial differences in the clinical presentation, depending on the phase and clinical form of schistosomiasis in which it occurs. Schistosomiasis can remain undiagnosed for a long period of time, with secondary clinical lesion. Here, we review the clinical profile of schistosomiasis. This information may aid in the development of more efficacious treatments and improved disease prognosis.
more
Full Perscribing information on Fexinidazole Tablet for oral use
INDICATIONS AND USAGE
Fexinidazole Tablets are indicated for the treatment of both the first-stage (hemolymphatic) and second-stage (meningoencephalitic) human African trypanosomiasis (HAT) due to Trypanosoma brucei gambiense in pati
...
ents 6 years of age and older and weighing at least 20 kg.
Limitations of Use
Due to the decreased efficacy observed in patients with severe second stage HAT (cerebrospinal fluid white blood cell count (CSF-WBC) >100 cells/μL) due to T. brucei gambiense disease, Fexinidazole Tablets should only be used in these patients if there are no other available treatment options [see Warnings and Precautions (5.1)]
more
PLoS Negl Trop Dis 15(8): e0009697. Chagas disease (CD), caused by the parasite Trypanosoma cruzi, affects ~6–7 million people worldwide. Significant limitations still exist in our understanding of CD. Harnessing individual participant data (IPD) from studies could support more in-depth analyses t
...
o address the many outstanding research questions. This systematic review aims to describe the characteristics and treatment practices of clinical studies in CD and assess the breadth and availability of research data for the potential establishment of a data-sharing platform.
more
Human echinococcosis is a zoonotic disease (a disease that is transmitted to humans from animals) that is caused by parasites, namely tapeworms of the genus Echinococcus.
Despite a historical association with poor tolerability, a comprehensive review on safety of antileishmanial chemotherapies is lacking. We carried out an update of a previous systematic review of all published clinical trials in visceral leishmaniasis (VL) from 1980 to 2019 to document any reported
...
serious adverse events (SAEs).
more
Foodborne trematode infections cause 2 million life years lost to disability and death worldwide every year.
People become infected by eating raw fish, crustaceans or vegetables that harbour the parasite larvae.
Foodborne trematodiases are most prevalent in East Asia and South America.
Foodborne
...
trematode infections result in severe liver and lung disease.
Safe and efficacious medicines are available to prevent and treat foodborne trematodiases.
Prevention and management of food-borne trematodes requires cross-sectoral collaboration on the human-animal and ecosystems interface.
more
Les procédures décrites dans cette POS concernent à la fois l'environnement dans lequel les tests
index sont effectués (par exemple, la construction d'une infrastructure qui garantit la confidentialité,
les formulaires disponibles sur place, le stockage des données physiques et numériques)
...
et
également les actions requises des agents de santé qui effectuent le test index. Les personnes
chargées de la mise en œuvre de ces POS devront également connaître les POS concernant
l'identification et la réponse face à la violence dans le contexte des tests index. Les recommandations
relatives au contenu des services d'intervention en cas de violence sont fournies en Annexe A
more
Le syndrome respiratoire aigu provoqué par le coronavirus-2 (SARS-CoV-2), initialement décrit en Chine, est responsable
de la pandémie que nous connaissons actuellement sous le nom de coronavirus disease 2019 ou COVID-19. L'épidémie de
coronavirus a été déclarée « urgence de santé publi
...
que mondiale » par l'Organisation mondiale de la santé (OMS) le 30 janvier 2020 . L'Afrique a été atteinte plus tard que les autres continents, mais à la date du 3 mai, tous les pays africains
avaient notifié au moins un cas. À la date du 09 juin 2020, l'Afrique comptait près de 200 000 cas confirmés, plus de
5000 décès, avec 25 pays ayant plus de 1000 cas actifs. Les patients atteints par ce virus peuvent développer des symptômes allant jusqu'à l'insuffisance respiratoire aiguë sévère
more
Leptospirosis is a perplexing conundrum for many. In the existing literature, the pathophysiological mechanisms pertaining to leptospirosis is still not understood in full. Considered as a neglected tropical zoonotic disease, leptospirosis is culminating as a serious problem worldwide, seemingly exi
...
sting as co-infections with various other unrelated diseases, including dengue and malaria. Misdiagnosis is also common as non-specific symptoms are documented extensively in the literature. This can easily lead to death, as the severe form of leptospirosis (Weil’s disease) manifests as a complex of systemic complications, especially renal failure. The virulence of Leptospira sp. is usually attributed to the outer membrane proteins, including LipL32. With an armament of virulence factors at their disposal, their ability to easily adhere, invade and replicate within cells calls for a swift refinement in research progress to establish their exact pathophysiological framework. As an effort to reconstitute the current knowledge on leptospirosis, the basis of leptospiral infection, including its risk factors, classification, morphology, transmission, pathogenesis, co-infections and clinical manifestations are highlighted in this review. The various diagnostic techniques are also outlined with emphasis on their respective pros and cons.
more
Chromoblastomycosis (CBM), represents one of the primary implantation mycoses caused by melanized fungi widely found in nature. It is characterized as a Neglected Tropical Disease (NTD) and mainly affects populations living in poverty with significant morbidity, including stigma and discrimination.
Diagnostic performance, cost-effectiveness, ease of performance, rapidity and in-field applicability of tests for Soil-transmitted helminth infections.
Snake bite is a neglected public health issue in many tropical and subtropical countries. About 5.4 million snake bites occur each year, resulting in 1.8 to 2.7 million cases of envenomings (poisoning from snake bites). There are between 81 410 and 137 880 deaths and around three times as many amput
...
ations and other permanent disabilities each year.
more
