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Strict storage recommendations for insulin are difficult to follow in hot tropical regions and even more challenging in conflict and humanitarian emergency settings, adding an extra burden to the management of people with diabetes. According to pharmacopeia unopened insulin vials must be stored in a
...
refrigerator (2–8°C), while storage at ambient temperature (25–30°C) is usually permitted for the 4-week usage period during treatment. In the present work we address a critical question towards improving diabetes care in resource poor settings, namely whether insulin is stable and retains biological activity in tropical temperatures during a 4-week treatment period. To answer this question, temperature fluctuations were measured in Dagahaley refugee camp (Northern Kenya) using log tag recorders. Oscillating temperatures between 25 and 37°C were observed. Insulin heat stability was assessed under these specific temperatures which were precisely reproduced in the laboratory. Different commercialized formulations of insulin were quantified weekly by high performance liquid chromatography and the results showed perfect conformity to pharmacopeia guidelines, thus confirming stability over the assessment period (four weeks). Monitoring the 3D-structure of the tested insulin by circular dichroism confirmed that insulin monomer conformation did not undergo significant modifications. The measure of insulin efficiency on insulin receptor (IR) and Akt phosphorylation in hepatic cells indicated that insulin bioactivity of the samples stored at oscillating temperature during the usage period is identical to that of the samples maintained at 2–8°C. Taken together, these results indicate that insulin can be stored at such oscillating ambient temperatures for the usual four–week period of use. This enables the barrier of cold storage during use to be removed, thereby opening up the perspective for easier management of diabetes in humanitarian contexts and resource poor settings.
more
The main objectives of the SOPs are to: (i) establish standards and timelines for response activities; and (ii) guide national governments and GPEI partners in key support functions.
This new version of the SOPs presents overall response requirements for dealing with type 1, 2 and 3 poliovirus fo
...
llowing monovalent type 2 oral polio vaccine (mOPV2) cessation. Version 2.4 will be valid until release of revised version 3.0 (anticipated May 2018).
more
COVID-19 has altered health sector capacity in low-income and middle-income countries (LMICs). Cost data to inform evidence-based priority setting are urgently needed. Consequently, in this paper, we calculate the full economic health sector costs of COVID-19 clinical management in 79 LMICs under di
...
fferent epidemiological scenarios.
more
Rural Housing Reconstruction Program Post-2005 Earthquake
Shahnaz Arshad; Sohaib Athar
Global Facility for Disaster Reduction and Recovery; The World Bank
(2013)
Learning from the Pakistan Experience. A Manual for Post-Disaster Housing Program Managers
The Kabeho Mwana project (2006–2011) supported the Rwanda Ministry of Health (MOH) in scaling up integrated community case management (iCCM) of childhood illness in 6 of Rwanda’s 30 districts. The project trained and equipped community health workers (CHWs) according to national guidelines. In p
...
roject districts, Kabeho Mwana staff also trained CHWs to conduct household-level health promotion and established supervision and reporting mechanisms through CHW peer support groups (PSGs) and quality improvement systems. The iCCM model implemented by Kabeho Mwana resulted in greater improvements in care-seeking than those seen in the rest of the country. Intensive monitoring, collaborative supervision, community mobilization, and CHW PSGs contributed to this success. The PSGs were a unique contribution of the project, playing a critical role in improving care-seeking in project districts. Effective implementation of iCCM should therefore include CHW management and social support mechanisms. Finally, re-analysis of national survey data improved evaluation findings by providing impact estimates.
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A recent survey of the literature and experience identified five broad actions that development institutions and governments, as well as their partners and stakeholders, can take to improve disability-inclusive disaster risk management. Those five actions are:
- Include persons with disabilitie ... s as valued stakeholders in disaster risk management activities
- Help remove barriers to the full participation of persons with disabilities
- Increase awareness among governments and their partners of the safety and security needs of persons with disabilities
- Collect data that is disaggregated by disability
- Ensure that new construction, rehabilitation and reconstruction are accessible to persons with disabilities more
- Include persons with disabilitie ... s as valued stakeholders in disaster risk management activities
- Help remove barriers to the full participation of persons with disabilities
- Increase awareness among governments and their partners of the safety and security needs of persons with disabilities
- Collect data that is disaggregated by disability
- Ensure that new construction, rehabilitation and reconstruction are accessible to persons with disabilities more
Disability Inclusion in Disaster Risk Management: Promising practices and opportunities for enhanced engagement
Guernsey, Katherine; Scherrer, Valérie
Global Facility for Disaster Reduction and Recovery (GFDRR), World Bank
(2018)
C1
This paper provides information to assist World Bank and GFDRR staff in affecting disability-inclusive DRM. It is based upon desk reviews of existing practice, as well as consultations with experts in the field of disability-inclusive DRM. The paper:
- Illustrates promising practices related to ... disability-inclusive DRM;
- Identifies key gaps in knowledge and practices;
- Identifies value-added areas for GFDRR and the World Bank, including specific actions they can take to advance the disability and social inclusion agenda in DRM;
It includess:
- Relevant guiding international policy frameworks;
- Disability inclusion in the priorities of the Sendai Framework for Disaster Risk Reduction; - Illustrations of promising practices in disability-inclusive DRM;
- An annex of resources related to disability and DRM. more
- Illustrates promising practices related to ... disability-inclusive DRM;
- Identifies key gaps in knowledge and practices;
- Identifies value-added areas for GFDRR and the World Bank, including specific actions they can take to advance the disability and social inclusion agenda in DRM;
It includess:
- Relevant guiding international policy frameworks;
- Disability inclusion in the priorities of the Sendai Framework for Disaster Risk Reduction; - Illustrations of promising practices in disability-inclusive DRM;
- An annex of resources related to disability and DRM. more
Department of Behavioural Medicine, Lagos State University College of Medicine Ikeja, Lagos Nigeria
Global Mental Health (2015), 2, e5, page 1 of 12. doi:10.1017/gmh.2015.8;
Received 29 January 2015; Revised 8 April 2015; Accepted 15 April 2015
Special issue: Mental Health Challenges in Lithuania
Nos. 1-2 '11
Борьба с туберкулезом в тюрьмах
IvanBastian, Martien Borgdorff, Tine Demeulenaere et al.
Global Tuberculosis Proqramme, World Health Organization
(2002)
C2
В помощь руководи*телям и практикующим врачам приведены конкретные меры, направ*ленные на улучшение медицинской помощи и обеспечение равногодоступа к не
...
й заключенных, необходимые юридические инструменты, рекомендации по организации работы лабораторных и противотубер*кулезных служб, методы диагностики и ведения больных, образцыспециальной документации, перечни профилактических и санитарно*просветительных мероприятий.
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Community-based strategies play a significant role in many health systems in low- and middle-income countries, especially in light of critical shortages in the health workforce. The term community health worker has been used to refer to volunteers and salaried, professional or lay health workers wit
...
h a wide range of training, experience, scope of practice and integration in health systems. In the context of this study, we use the term community-based practitioner (CBPs) to reflect the diverse nature of these cadres of health workers.
CBPs provide preventive, promotive, curative and palliative services across a range of areas, including reproductive, maternal, newborn and child health, HIV, tuberculosis, malaria, control of other endemic diseases, and noncommunicable diseases. Significant evidence has emerged over the past two decades on their effectiveness, which has triggered interest in the potential to use their services to expand access to care, in particular in rural and underserved areas where deployment and retention of more qualified health workers is problematic. Calls have been made to integrate CBP programmes in human resources and health strategies, and to scale up rapidly the extent and coverage of CBP initiatives.
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GGGI Technical Guideline No. 2
The marathon to eradicate polio is on its final lap: the world is more than 99% of the way to success. After millennia of living with poliovirus and suffering the paralysis it causes, today nearly all the world’s people live in polio-free countries; two of the three strains of wild poliovirus (WPV
...
) have been eradicated. Some 20 million people are walking who would have been paralysed had it not been for the efforts of national governments and health workers. If eradicating polio has been a marathon, the finishing line is in sight.
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The strengthened plan aims to achieve and sustain a polio-free world through a focus on implementation and accountability. Emphasis will be on cutting outbreak response times; increasing vaccine demand; transforming campaign effectiveness; working systematically through integration; increasing acce
...
ss in inaccessible areas; transitioning towards government ownership; and improving decision-making and accountability.
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This Guidance Note is meant to help protection cluster coordinators apply nexus approaches in a practical way by, providing concrete steps and means to address prevalent or longstanding protection issues, risk patterns, trends and chronic vulnerabilities. The guidance calls for a practical, problem-
...
solving approach that seeks opportunities to identify and collaborate with actors beyond the humanitarian sphere to address deep-rooted protection issues
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Health financing for the COVID-19 response: Process guide for national budgetary dialogue. ACT-A Health Systems Connector
World Health Organization (WHO), World Bank, Global Financing Facility (GFF) et al.
World Health Organization (WHO)
(2021)
CC
Annual and medium-term budget preparation processes are the platforms through which specific plans are transformed into actual resource allocation decisions. The aim of this Process Guide is to support key stakeholders involved in these processes (such as the Cabinet, Ministries of Finance and Healt
...
h, the Parliament, citizens, media, and civil society organizations) to reorient budgetary arrangements in order to facilitate the ability of national governments to respond to the COVID-19 pandemic by delivering, therapeutics, diagnostics, and vaccine services to their populations. Reorienting budgetary arrangements positions governments to sustain the capacity to mitigate and respond to COVID-19 while concurrently delivering other essential health services and working towards Universal Health Coverage (UHC). The reorientation process is an opportunity to better align budgetary arrangements to sustain systemic capacity to prevent emerging health threats over the short, medium, and long terms.
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