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Manufacturing, safety and quality control of vaccines

World Health Organization WHO (2020) C_WHO
This document is part three in a series of explainers on vaccine development and distribution. Part one focused on how vaccines work to protect our bodies from disease-carrying germs. Part two focused on the ingredients in a vaccine and the three clinical trial phases. This document outlines the... more
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Global consultation of National Leprosy Programme managers, partners and affected persons on Global Leprosy Strategy 2021–2030

World Health Organization WHO (2020) C_WHO
The World Health Organization organized a Consultation of National Leprosy Programme managers, partners and affected persons to discuss the draft Global Leprosy Strategy, 2021--2030. This virtual event took place from 26 to 30 October 2020. It was attended by more than 450 stakeholders. Contribution... more
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Rapid communication on the systematic screening for tuberculosis

World Health Organization WHO (2020) C_WHO
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Leprosy/Hansen disease: Contact tracing and post-exposure prophylaxis
recommended

World Health Organization WHO (2020) C_WHO
This document provides guidance on how to implement contact screening and chemoprophylaxis with single-dose rifampicin. The contents are logically ordered: counselling and obtaining consent, identification and listing of index case, listing of contacts, tracing of contacts, screening of contacts, ad... more
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WHO guidelines on physical activity and sedentary behaviour

World Health Organization WHO (2020) C_WHO
The WHO Guidelines on physical activity and sedentary behaviour provide evidence-based public health recommendations for children, adolescents, adults and older adults on the amount of physical activity (frequency, intensity and duration) required to offer significant health benefits and mitigate he... more
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HIV drug resistance surveillance in countries scaling up pre-exposure prophylaxis

World Health Organization WHO (2020) C_WHO
WHO recommends that pre-exposure prophylaxis (PrEP) be offered as an additional prevention choice for HIV-negative individuals at substantial risk of HIV infection as part of combination prevention approaches. HIV drug resistance has been rarely reported among PrEP users who tested HIV positive i... more
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Technical brief on water, sanitation, hygiene (WASH) and wastewater management to prevent infections and reduce the spread of antimicrobial resistance (AMR)

World Health Organization WHO, Food and Agriculture Organization FAO, World Organization for Animal Health OIE (2020) C_WHO
Improvements in water sanitation and hygiene (WASH) and wastewater management in all sectors are critical elements of preventing infections and reducing the spread of antimicrobial resistance (AMR) as identified in the Global Action Plan to combat AMR. Yet, at present, WASH and wastewater management... more
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WHO recommendation on advance misoprostol distribution to pregnant women for prevention of postpartum haemorrhage

World Health Organization (2020) C_WHO
The recommendation in this document thus supersedes the previous WHO recommendation for the prevention of PPH as published in the 2012 guideline, WHO recommendations for the prevention and treatment of postpartum haemorrhage.
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WHO recommendation on routes of oxytocin administration for the prevention of postpartum haemorrhage after vaginal birth

World Health Organization WHO (2020) C_WHO
The recommendation in this document thus supersedes the previous WHO recommendation for the prevention of PPH as published in the 2012 guideline
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WHO recommendation on umbilical vein injection of oxytocin for the treatment of retained placenta

World Health Organization (2020) C_WHO
The recommendation in this document thus supersedes the previous WHO recommendation for the prevention of PPH as published in the 2012 guideline, WHO recommendations for the prevention and treatment of postpartum haemorrhage.
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Introducing and scaling up testing for human papillomavirus as part of a comprehensive programme for prevention and control of cervical cancer

World Health Organization WHO (2020) C_WHO
This guidance is intended to be used by programme managers following the decision to introduce human papillomavirus (HPV) virological testing as a screening assay in their national cervical cancer prevention and control programme. The guidance includes a step-by-step process to be followed after the... more
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South-East Asia Regional Action Plan on Programmatic Management of Latent Tuberculosis Infection

World Health Organization (WHO), Regional Office for South-East Asia (2020) C_WHO
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WHO/HIVRESNET HIV drug resistance - laboratory operational framework

World Health Organization WHO (2020) C_WHO
The aim of the operational framework is to ensure 1) accurate collection, handling, shipment and storage of specimens collected in countries implementing HIV drug resistance surveillance; and 2) the availability of quality-assured HIV genotyping laboratory services producing comparable and reliable ... more
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Whole-genome sequencing for surveillance of antimicrobial resistance

World Health Organization WHO; Global Antimicrobial Resistance and Use Surveillance System (GLASS) (2020) C_WHO
Whole-genome sequencing (WGS) provides a vast amount of information and the highest possible resolution for pathogen subtyping. The application of WGS for global surveillance can provide information on the early emergence and spread of AMR and further inform timely policy development on AMR control.... more
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Global report on the epidemiology and burden of sepsis: Current evidence, identifying gaps and future directions

World Health Organisation (2020) CC
Sepsis contributes significantly to preventable mortality and is the final common pathway to death for severe infectious diseases; it can also arise as a complication of injuries and non-communicable diseases.
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Corticosteroids for COVID-19

World Health Organization WHO (2020) C_WHO
WHO published guidance for clinicians and health care decision-makers on the use of corticosteroids in patients with COVID-19. We recommend systemic corticosteroids for the treatment of patients with severe and critical COVID-19. We suggest not to use corticosteroids in the treatment of patients ... more
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Group Problem Managment Plus(GROUP PM+)

World Health Organization WHO (2020) C_WHO
Group psychological help for adults impaired by distress in communities exposed to adversity With this manual, the World Health Organization (WHO) is responding to requests from colleagues around the world for a group version of the manual Problem Management Plus (PM+), which was developed for adul... more
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Implementation manual to support the prevention of surgical site infections at the facility level: turning recommendations into practice
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World Health Organization WHO (2020) C_WHO
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Nutritional interventions update: multiple micronutrient supplements during pregnancy

World Health Organization WHO (2020) C_WHO
The World Health Organization’s comprehensive antenatal care (ANC) guideline WHO recommendations on antenatal care for a positive pregnancy experience was published in 2016 with the objective of improving the quality of routine health care that all women and adolescent girls receive during pregnan... more
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A step-by-step Guide to develop National Action Plans for Noma Prevention and Control in Priority Countries

World Health Organisation (WHO) (2020) C_WHO
Noma (cancrum oris) is a severe gangrenous disease of the mouth and face. It mostly affects children between the ages of 2 and 6 years living in extreme poverty. In addition to the known factors such as malnutrition, lack of vaccination in children and poor oral hygiene, several social and environme... more