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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Nurses & Midwives: The Frontline Against HIV/AIDS

ICAP Nurse Capacity Initiative ICAP (2013) CC

HOW ICAP IS BUILDING NURSING AND MIDWIFERY CAPACITY AND STRENGTHENING HEALTH SYSTEMS

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2020 South Sudan Humanitarian Needs Overview

Humanitarian Programe cycle 2020 Humanitarian Programe cycle 2020 (2019) CC

Context and impact of the crisis A year after the signing of the Revitalized Agreement on the Resolution of the Conflict in South Sudan (R-ARCSS),1 the ceasefire holds in most parts of the country. Armed conflict between State security forces and opposition armed groups has been contained to a sma... more

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The Condition of the Girl Child worldwide - Fifth Edition

Indefes - Terre des Hommes (2016) C1

In the last five years, i.e. how old turned the Campaign “Indifesa” (Defenceless) in 2016, that was launched by Terre des Hommes in 2012, the world has become smaller. One can actually say that the derangements following the Arab Spring in 2011 reshuffled what is stable and what produces instabi... more

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Socio-Economic Challenges of Persons with Disabilities: A Case Study of Ethiopia

Sedeto M H; Dar M J Global Journal of Human-Social Science (2019) C1

Abstract-The paper precisely and briefly explains the socio-economic challenges of persons with disabilities with focus on Ethiopia. The findings of the paper also indicates that, across the countries persons with disabilities have poorer health accesses, lower education achievements,... more

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Money & Microbes: Strengthening clinical research capacity to prevent epidemics

International Vaccines Task Force (IVTF) (2018) C1

Robust clinical research capacity in low- and middle-income countries is key to stemming the spread of epidemics, according to a new report from the International Vaccines Task Force (IVTF). The report lays out how to develop the political support, financing and coordination required to build this c... more

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Antimicrobials use, reistance and containment baseline survey (Ethiopia)

Drug Administration and Control Authority of Ethiopia , et al. (2009) C1

Emergence of antimicrobial resistance is a result of the use, overuse and misuse of antibiotics both in humans and animals. In Ethiopia, there are indications on the misuse of antibiotics by health care providers’, unskilled practitioners, and drug consumers. These coupled with rapid spread of res... more

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Security Management and Capacity Development: International agencies working with local partners

Singh, Iesha; European Interagency Security Forum (EISF) (2012) C2

This EISF report provides an analysis of the issues surrounding the relationship between NGO’s and their local partners. It includes a section on the topic and its background, responsabilities towards the partner organisation and particularly in terms of security, how to enable and help the partne... more

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Count me in! Inclusive WASH in Ethiopia

OpenWASH The Open University UKWaterAid (2018) C1

This Module, Count me in! Inclusive WASH in Ethiopia, was prepared by Ethiopian authors with support from The Open University UK. It was first published in June 2018. The contributors of original material are:Girma Aboma, Manager, GAA Economic Development ConsultBethel Shiferaw, SPCC Disability Incl... more

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Ethiopia - Multi-Sectorial Cholera Elimination Plan 2022 - 2028

Government of Ethiopia (2023) C2

The Ethiopia Multi-Sectorial Cholera Elimination Plan (2022-2028) outlines a national strategy to eliminate cholera in Ethiopia by 2028. The plan follows the Global Roadmap to End Cholera by 2030 and is based on six key pillars: Leadership & Coordination, Water, Sanitation & Hygiene (WASH), Surveill... more

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Introduction to Professional Nursing and Ethics

Amsale Cherie, Ato Hussen Mekonen, Tsehay Shimelse (2005) CC

Nurses at present are facing various personal, interpersonal, professional, institutional and socio cultural challenges in their professional performance. Dealing with these issues may not be always clear. The lack of one correct approach in addressing different conte... more

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Guide for the Medical, Veterinary and allied Professions

Bishop, G.; Durrheim, D.; Kloeck, P. et al. Department: Agriculture, Foresty and Fisheries - Republic of South Africa (2010) CC

Rabies is a disease of animals but too often the outcome is gauged in terms of human suffering and death. Despite this, in areas of the world where rabies is endemic there is often a lack of communication between veterinary and medical professionals, to the extent that the disease continues to thri... more

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HIV/AIDS strategic plan 2015-2020 in an investment case approach

Federal HIVAIDS Prevention and Control Office, Ethiopia (2014) C1

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Green City Development Guidelines

Global Green Growth Institute - GGGI (2018) CC

GGGI Technical Guideline No. 2

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Differentials of Early Teenage Pregnancy in Ethiopia, 2000, and 2005.

Ayele, Wubegzier Mekonnen ICF International (2013) C2

DHS Working Papers No. 90.

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Community-based rehabilitation: cBr guidelines - Introductory booklet (thai)

Kamala Achu, Kathy Al Jubah, Svein Brodtkorb, et al. WHO (2010) C_WHO

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Smallholder Farmers’ Perceptions of Climate Change and Adaptation Practices for Maize Production in Eastern Ethiopia

Teshome H.; Tesfaye K.; et al. (2021) CC

Climate change and variability is affecting maize (Zea mays L.) production in eastern Ethiopia but how farmers perceive the challenge and respond to it is not well documented. A study was conducted to analyze smallholder maize farmers’ perception of climate change/variability and identify their ad... more