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Use of the WHO Access, Watch, and Reserve classification to define patterns of hospital antibiotic use (AWaRe): an analysis of paediatric survey data from 56 countries

Hsia Y., B. R Lee, A. Versporten, et al The Lancet (2019) C2

Improving the quality of hospital antibiotic use is a major goal of WHO’s global action plan to combat antimicrobial resistance. The WHO Essential Medicines List Access, Watch, and Reserve (AWaRe) classification could facilitate simple stewardship interventions that are widely applicable globally.... more

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Young doctors’ perspectives on antibiotic use and resistance: a multinational and inter-specialty cross-sectional European Society of Clinical Microbiology and Infectious Diseases (ESCMID) survey

Beovic B., M. Dousak, C. Pulcini et al. Oxford University Press (2019) C2

Antibiotic resistance has been recognized as a major global health threat and optimizing prescribing is one of the most effective measures to preserve the effectiveness of antibiotics. The quality of prescribing depends mostly on those prescribers belonging to clinical medical specialties... more

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How to start an antimicrobial stewardship programme in a hospital

Mendelson M. , A.M. Morris , K. Thursky et al. (2019) C2

Antimicrobial stewardship (AMS) describes a coherent set of actions that ensure optimal use of antimicrobials to improve patient outcomes, while limiting the risk of adverse events (including antimicrobial resistance (AMR)). Introduction of AMS programmes in hospitals is part of most national action... more

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Heat waves and human health

Lee, V.; F. Zermoglio; K.L.Ebi; et al. USAID (2019) C1

Emerging evidence and experience to inform risk management in a warming world

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Burden of disease from inadequate water, sanitation and hygiene for selected adverse health outcomes: An updated analysis with a focus on low- and middle-income countries

Prüss-Ustün A., Wolf J., Bartram J., et al. (2019) CC

Int J Hyg Environ Health. 2019 Jun; 222(5): 765–777. doi: 10.1016/j.ijheh.2019.05.004; To develop updated estimates in response to new exposure and exposure-response data of the burden of diarrhoea, respiratory infections, malnutrition, schistosomiasis, malaria, soil-transmitted helminth infec... more

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Ilajnasy. Online Psychotherapy

Lange, A.; P. Emmelkamp, et al. (2019) C1

In den letzten Jahrzehnten hat es im westlichen Raum eine ganze Reihe web-basierter Therapieangebote gegeben. Die Entwicklung und Erforschung eines der ersten web-basierten Therapiemanuale (Interapy) wurde in den Niederlanden unter der Leitung von Prof. Dr. Alfred Lange und Prof. Dr. Paul Emmelkamp ... more

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Green spaces and mortality: a systematic review and meta-analysis of cohort studies

Rojas-Rueda, D.; M.J. Nieuwenhuijsen, M. Gascon; et al. (2019) CC

Lancet Planet Health 2019; 3: 469–77

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Biodiversity and Health in the Face of Climate Change

Marselle M., Stadler J., Korn H., et al. (2019) CC

The biosphere underlies the whole sustainable development concept, as the layer on which society and the economy rely. Nature and biodiversity fuel the natural cycles and life-support systems of the planet, on which humanity ultimately depends.

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Achieving the 17 Sustainable Development Goals within 9 planetary boundaries

Randers, J.; Rockström, J.; Stoknes, P. E.; et al. (2019) CC

The world agreed to achieve 17 Sustainable Development Goals by 2030. Nine planetary boundaries set an upper limit to Earth system impacts of human activity in the long run. Conventional efforts to achieve the 14 socio-economic goals will raise pressure on planetary boundaries, moving the world away... more

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Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map

Van Katwyk, S. R.; Grimshaw, J. M.; et al (2019) C2

BACKGROUND: Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to reduce antimicrobial overuse. A systematic evidenc...e map can support governments in making evidence-informed decisions about implementing programs to reduce AMR, by identifying, describing, and assessing the full range of evaluated government policy options to reduce antimicrobial use in humans. METHODS AND FINDINGS: Seven databases were searched from inception to January 28, 2019, (MEDLINE, CINAHL, EMBASE, PAIS Index, Cochrane Central Register of Controlled Trials, Web of Science, and PubMed). We identified studies that (1) clearly described a government policy intervention aimed at reducing human antimicrobial use, and (2) applied a quantitative design to measure the impact. We found 69 unique evaluations of government policy interventions carried out across 4 of the 6 WHO regions. These evaluations included randomized controlled trials (n = 4), non-randomized controlled trials (n = 3), controlled before-and-after designs (n = 7), interrupted time series designs (n = 25), uncontrolled before-and-after designs (n = 18), descriptive designs (n = 10), and cohort designs (n = 2). From these we identified 17 unique policy options for governments to reduce the human use of antimicrobials. Many studies evaluated public awareness campaigns (n = 17) and antimicrobial guidelines (n = 13); however, others offered different policy options such as professional regulation, restricted reimbursement, pay for performance, and prescription requirements. Identifying these policies can inform the development of future policies and evaluations in different contexts and health systems. Limitations of our study include the possible omission of unpublished initiatives, and that policies not evaluated with respect to antimicrobial use have not been captured in this review. CONCLUSIONS: To our knowledge this is the first study to provide policy makers with synthesized evidence on specific government policy interventions addressing AMR. In the future, governments should ensure that AMR policy interventions are evaluated using rigorous study designs and that study results are published. more

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Development and validation of DSM-5 based diagnostic tool for children with Autism Spectrum Disorder

Sheffali Gulati , Jaya Shankar Kaushik, Lokesh Saini, et al. (2019) CC

PLoSONE 14(3):e0213242.https://doi.org/10.1371/journal.pone.0213242

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Kairos for Creation - Confession Hope for Earth

Andrianos, L.; M.Biehl, R. Gütter ,et al. Brot für die Welt; WCC; EKD; et al. (2019) CC

The “Wuppertal Call” – Contributions and Recommendations from an International Conference on Eco-Theology and Ethics of Sustainability Wuppertal, Germany, 16 – 19 June 2019

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Lifestyle Diseases – An Increasing Cause Of Health Loss

Helen K., Gladwell G., Calestus N. and Wangia E. UNFPA, WHO, World Bank, et al. (2019) C1

Kenya in undergoing an epidemiological transition marked by a decline in morbidity and mortality due to communicable conditions, and an increase in the burden of non-communicable diseases (NCDs), which include diseases such as diabetes, cancers, cardiovascular diseases and chronic respiratory infect... more

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Improved social services and the burden of post-traumatic stress disorder among economically vulnerable people after a natural disaster: a modelling study

Gregory H Cohen, Shailesh Tamrakar, Sarah Lowe, et al. (2019) CC

Lancet Planet Health 2019; 3: e93–101

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Countdown Global Mental Health 2030

Saxena, S.; D. Kestel, C. Sunkel, et al. (2019) CC

Lancet, Published:February 21, 2019DOI:https://doi.org/10.1016/S0140-6736(19)30424-6. This article announce the establishment of Countdown Global Mental Health, an independent, multistakeholder monitoring and accountability collaboration for mental health, within an initial timeframe of the UN Sust... more

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Resurgence of Vaccine-Preventable Diseases in Venezuela as a Regional Public Health Threat in the Americas

Paniz-Mondolfi, A.E.; A. Tami, M.E. Grillet, et al. (2019) C_CDC

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Understanding and building resilience to early life trauma in Belarus and Ukraine

Marais, J.F.; Ol. Kazakova, D. Krupchanka, et al. World Health Organization WHO, Regional Office of Europe (2019) C_WHO

In 2018 and early 2019, the WHO Regional Office for Europe’s cultural contexts of health and well-being project worked alongside the University of Exeter’s WHO Collaborating Centre on Culture and Health, the Minsk Regional Centre for Psychiatry and Addiction, and the Institute of Mental Health o... more

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Понимание и работа с ранней детской травмой в Беларуси и Украине

Marais, J.F.; Ol. Kazakova, D. Krupchanka, et al. World Health Organization WHO, Regional Office of Europe (2019) C_WHO

Understanding and building resilience to early life trauma in Belarus and Ukraine In 2018 and early 2019, the WHO Regional Office for Europe’s cultural contexts of health and well-being project worked alongside the University of Exeter’s WHO Collaborating Centre on Culture and Health, the Minsk... more

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Tracking global trends in the effectiveness of antibiotic therapy using the Drug Resistance Index

Klein E.Y., K. K .Tseng, S. Pant, et al. BMJ Global Health (2019) C2

BMJ Global Health, Vol. 4 (2019) no.2 Antibiotic resistance is threatening global health, development and food security; however, measures for assessing and communicating the threat of resistance are lacking. The Drug Resistance Index (DRI) allows for global assessment of the relative efficacy of ... more

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The proposed Drug Resistance Index (DRI) is not a good measure of antibiotic effectiveness in relation to drug resistance

C. M J E Vandenbroucke-Grauls, G. Kahlmeter, J. Kluytmans et al. BMJ Global Health (2019) C2

BMJ Global Health Vol.4 (2019 no.4 The Drug Resistance Index (DRI) is proposed as measure of antibiotic effectiveness in a given country, by combining, in a single metric the use of various antibiotic groups and the resistance proportions of several pathogens.It is a complicated measure that gives ... more