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Antimalarial chemotherapy is crucial for reducing morbidity, mortality, and drug resistance, and is the cornerstone of malaria control. Existing antimalarial drugs act at different stages of the parasite’s life cycle. These drugs range from classic agents such as chloroquine and quinine to newer a
...
rtemisinin derivatives. They include tissue schizonticides, blood schizonticides, gametocytocides, and sporontocides. Artemisinin and its derivatives are the most effective and fastest-acting treatment against drug-resistant Plasmodium falciparum, achieving rapid parasite clearance and reducing transmission potential. Other key drugs include mefloquine, halofantrine, proguanil, sulfadoxine–pyrimethamine, atovaquone–proguanil, tetracyclines, clindamycin and azithromycin. Each of these drugs has a specific mechanism of action, pharmacokinetics, efficacy, safety profile and contraindications. Rational drug combinations and adherence to national treatment guidelines are essential for managing resistance, ensuring safety in vulnerable populations such as children and pregnant women, and optimising therapeutic outcomes in cases of both uncomplicated and severe malaria.
more
On Global Handwashing Day, WHO and UNICEF have released the first-ever global Guidelines on Hand Hygiene in Community Settings to support governments and practitioners in promoting effective hand hygiene outside health care – across households, public spaces and institutions. Framing hand hygiene
...
as a public good and a government responsibility, the Guidelines translate evidence into ready-to-adopt actions that enable sustainable access to effective hygiene services. This will reduce diarrhoeal disease, acute respiratory infections and other preventable illnesses, strengthening routine public health where people live, work, visit and study, and emergency preparedness, including outbreaks like cholera.
Despite clear benefits, 1.7 billion people still lacked basic hand hygiene services at home in 2024, including 611 million with no facility at all. Meeting the 2030 target will require accelerated progress – about a doubling in the global rate, and much faster in specific settings (up to 11-fold in least-developed countries and 8-fold in fragile contexts). Hand hygiene remains one of the most cost-effective health investments, reducing diarrhoea by 30% and acute respiratory infections by 17%, with large, measurable gains for population health.
“Clean hands save lives, but results at scale require policy, financing and accountability,” said Dr Ruediger Krech, Director a.i, Department of Environment, Climate Change, One Health & Migration at the World Health Organization. “These Guidelines help countries move beyond fragmented projects to government-led systems that make soap, water, and conditions conducive to everyday hand hygiene the norm.”
“Children and young people pay the highest price when basic hygiene is out of reach,” said Cecilia Scharp, Director, Water Sanitation and Hygiene (WASH) Team, Programme Group, UNICEF. “These Guidelines provide practical steps to ensure facilities are accessible when they need to be – in homes, schools, markets, and transport hubs – so every child can learn, play and thrive with dignity.”
more
In the battle against diseases like Zika and dengue, knowledge is power. Climate change is shifting the
distribution of mosquitoes and to new areas. Empowering communities is essential in reaching and pro-
tecting the most vulnerable individuals and households. Vector control programmes, community
...
empow-
erment and awareness campaigns are proven strategies to reduce the burden of vector-borne diseases.
Red Cross and Red Crescent volunteers can play a key role in community and school outreach activities for Zika, dengue and chikungunya prevention. These community-based activities need to be sustained to
ensure long-lasting disease control.
more
The advent of point-of-care (POC) EID technologies is a breakthrough that creates the opportunity to increase coverage of EID testing. It will allow same-day test results and enable the initiation of earlier treatment, as well as address some of the key limitations of conventional EID networks – i
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n particular long turnaround times for tests and high rates of loss to follow up.
WHO/HIV/2017.16
more
Accessed: 30.10.2019
Accessed: 30.10.2019
Accessed: 30.10.2019
Accessed: 30.10.2019
The Bravest Boy I Know (Le garçon le plus courageux que je connaisse) est l'histoire de deux amis, Kendi et Kayla. Kendi vit avec le VIH. L'histoire, qui se déroule en Afrique et est illustrée par le célèbre artiste Sujean Rim, montre qu'en prenant leurs médicaments, les enfants vivant avec le
...
VIH peuvent mener une vie saine. Le livre est narré par le chanteur sud-africain Loyiso Bala et Annah Sango, une jeune militante du Zimbabwe et membre de la Communauté internationale des femmes vivant avec le VIH
more
Traitement pré-transfert par l'artésunate rectal dans le paludisme infantile
recommended
M. Gomes
Programme Spécial de Recherche et de Formation concernant les Maladies Tropicales (TDR), Organisation mondiale de la Santé
(2012)
CC
Manuel de formation pour les agents de santé communautaire pour l'évaluation des signes de danger et l'administration d'un traitement préalable au transfert immédiat vers une structure de santé.
Ce manuel a été développé par le Programme Spécial de Recherche et de Formation concernant l
...
es Maladies Tropicales (TDR) pour aider à la formation des Agents de Santé Communautaire (ASC) sur l'utilisation de l'artésunate par voie rectale comme traitement de pré-transfert.
Ceci est fondé sur la stratégie de prise en charge intégrée des maladies de l'enfant (lMCI), et une publication antérieure "Caring for the sick child in the community» qui avait été produite par le Département Santé de la mère, du nouveau-né, de l'enfant et de l'adolescent de l'OMS.
more
El documento ayudará a los países a identificar las áreas de necesidades y determinar cómo se puede reforzar la red de entomología, especialmente en el contexto de un sistema de salud descentralizado. Las recomendaciones también tienen en cuenta los diferentes grados de desarrollo y las difere
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ntes investigaciones entomológicas necesarias para dar soporte a las acciones de prevención y control de las enfermedades.
more
Les cartes de référence sur la communication
interpersonnelle pour la vaccination ont été créées
pour faciliter l’accès à l’information sur les vaccins et
les maladies évitables par la vaccination. Ces cartes
peuvent servir d’outils d’auto-apprentissage, de guides
pour les conv
...
ersations avec les personnes qui s’occupent
d’un enfant et les membres de la communauté, ou de
ressources d’information pour l’éducation et la formation.
Accessed on 20/06/2025.
more
Das neue Coronavirus Kindern einprägsam erklärt. Was sind Viren? Wie soll man sich verhalten? Und warum ist das so wichtig?
To support countries in adapting their response to different COVID-19 scenarios, the World Health Organization (WHO) Department of Maternal, Newborn, Child and Adolescent Health and Ageing commissioned this scoping review of published and grey literature. The objective was to identify interventions
...
implemented to maintain the provision and use of essential services for MNCAAH during disruptive events and to summarize lessons learned during these interventions. The review included outbreaks of Ebola virus disease (EVD), severe acute respiratory syndrome (SARS), Zika virus disease (ZVD), the ongoing COVID-19 pandemic, and natural disasters and humanitarian emergencies that caused disruption to services, transport and other activities.
more
Information note. In 2021, preliminary results of observational studies from the Community Access to Rectal Artesunate for Malaria (CARAMAL) project did not confirm the mortality impact observed in the controlled trial in 2009. Consequently, in January 2022, WHO released an information note on recta
...
l artesunate (RAS), suggesting immediate risk mitigation measures. To provide clarity on the evidence, WHO subsequently convened independent experts to conduct a formal evidence review of the data from the CARAMAL project, as well as data from other studies evaluating the deployment of pre-referral RAS at programmatic level
more
Update, 2023. En 2021, les résultats préliminaires des études d’observation du projet CARAMAL (Community Access to Rectal Artesunate for Malaria) n’ont pas confirmé l’impact sur la mortalité observé dans l’essai contrôlé de 2009. Par conséquent, en janvier 2022, l’OMS a publié un
...
e note d’information sur l’artésunate rectal, dans laquelle elle suggérait des mesures immédiates d’atténuation des risques.
more
Adolescence, defined as the period between 10 and 19 years of age, is a developmental stage during which many psychosocial and mental health challenges emerge. There is a well-established link between mental health and HIV outcomes. Adolescents and young adults living with HIV typically have additio
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nal mental health needs linked to their experiences of living with and managing a chronic illness, along with prevailing stigma and discrimination. Mental health promotion and prevention is thus a critical priority for this group.
more
Key facts
- A healthy diet helps to protect against malnutrition in all its forms, as well as noncommunicable diseases (NCDs), including diabetes, heart disease, stroke and cancer.
- Unhealthy diet and lack of physical activity are leading global risks to health.
- Healthy dietary practices start
...
early in life – breastfeeding fosters healthy growth and improves cognitive development, and may have longer term health benefits such as reducing the risk of becoming overweight or obese and developing NCDs later in life.
- Energy intake (calories) should be in balance with energy expenditure. To avoid unhealthy weight gain, total fat should not exceed 30% of total energy intake (1, 2, 3). Intake of saturated fats should be less than 10% of total energy intake, and intake of trans-fats less than 1% of total energy intake, with a shift in fat consumption away from saturated fats and trans-fats to unsaturated fats (3), and towards the goal of eliminating industrially-produced trans-fats (4, 5, 6).
- Limiting intake of free sugars to less than 10% of total energy intake (2, 7) is part of a healthy diet. A further reduction to less than 5% of total energy intake is suggested for additional health benefits (7).
- Keeping salt intake to less than 5 g per day (equivalent to sodium intake of less than 2 g per day) helps to prevent hypertension, and reduces the risk of heart disease and stroke in the adult population (8).
- WHO Member States have agreed to reduce the global population’s intake of salt by 30% by 2025; they have also agreed to halt the rise in diabetes and obesity in adults and adolescents as well as in childhood overweight by 2025 (9, 10).
more
About Cystic Fibrosis - What is Cystic Fibrosis?
South Africa Cystic Fibrosis Association (SACFA)
South African Cystic Fibrosis Association (SACFA)
(2024)
CC2
The South African Cystic Fibrosis Association (SACFA) is a non-profit organization dedicated to supporting individuals with cystic fibrosis (CF) in South Africa. Their website provides comprehensive information about CF, including its causes, symptoms, and treatment options. CF is described as an in
...
herited genetic disorder that primarily affects the lungs and pancreas, leading to the production of thick, sticky mucus that can cause severe respiratory and digestive issues. The site emphasizes the importance of early diagnosis and proper management to improve the quality of life for those affected. Additionally, SACFA outlines its mission to raise public awareness, promote medical advancements, and offer support to the CF community through various initiatives and resources.
more
