stas Pranchas para o diagnóstico de parasitos intestinais destinam-se a servir tanto como orientação para profissionais de laboratório e de campo em países endêmicos quanto como material de ensino para estudantes e estagiários. Contêm orientações sobre a escolha da preparação para os d...iferentes métodos copromicroscópicos e a principal técnica de coloração para o diagnóstico de parasitos intestinais (nematoides, trematódeos, cestódeos e protozoários). As fotomicrografias mostram a aparência e as características diagnósticas dos diversos parasitos nas diferentes preparações. As pranchas foram produzidas em formato plastificado impermeável, resistente e fácil de usar na bancada. São recomendadas para todos os profissionais de saúde que atuam na rotina de diagnóstico de parasitoses intestinais
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based on the WHO Bench Aids for the diagnosis of intestinal parasites;
Tutor’s Guide: perform specific laboratory techniques; identify intestinal parasites by genus and species; quantify helminth eggs in faeces by Kato-Katz procedure.
El manual detalla los procedimientos más apropiados para el diagnóstico de los enteroparásitos descritos en nuestro medio y se espera que sea una ayuda inmediata para el personal técnico y profesional de los laboratorios locales, intermedios y regionales de la Red Nacional de Laboratorios en Sal...ud Pública del país.
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Chapter 6 contents
Malaria
Human African trypanosomiasis (sleeping sickness)
American trypanosomiasis (Chagas disease)
Leishmaniases
Intestinal protozoan infections (parasitic diarrhoea)
Flukes
Schistosomiases
Cestodes
Nematode infections
Filariasis
...
Onchocerciasis (river blindness)
Loiasis.
Lymphatic filariasis (LF)
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Schistosomiasis is a chronic parasitic infection caused by worms. It is most common in rural and impoverished populations. In the Americas, the parasite species is Schistosoma mansoni, which is associated with intestinal schistosomiasis. The main risk factor for infection is exposure through househo...ld, work, or recreational activities in fresh water contaminated with faeces from infected humans.
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This review focusses on the interactions between the etiologic agent of Chagas disease, Trypanosoma cruzi, and its triatomine vector. The flagellate mainly colonizes the intestinal tract of the insect. The effect of triatomines on trypanosomes is indicated by susceptibility and refractoriness phenom...ena that vary according to the combination of the strains. Other effects are apparent in the different regions of the gut. In the stomach, the majority of ingested blood trypomastigotes are killed while the remaining transform to round stages. In the small intestine, these develop into epimastigotes, the main replicative stage. In the rectum, the population density is the highest and is where the infectious stage develops, the metacyclic trypomastigote. In all regions of the gut, starvation and feeding of the triatomine affect T. cruzi. In the small intestine and rectum, starvation reduces the population density and more spheromastigotes develop. In the rectum, feeding after short-term starvation induces metacyclogenesis and after long-term starvation the development of specific cells, containing several nuclei, kinetoplasts and flagella. When considering the effects of T. cruzi on triatomines, the flagellate seems to be of low pathogenicity. However, during stressful periods, which are normal in natural populations, effects occur often on the behaviour, eg, in readiness to approach the host, the period of time before defecation, dispersal and aggregation. In nymphs, the duration of the different instars and the mortality rates increase, but this seems to be induced by repeated infections or blood quality by the feeding on infected hosts. Starvation resistance is often reduced by infection. Longevity and reproduction of adults is reduced, but only after infection with some strains of T. cruzi. Only components of the surface coat of blood trypomastigotes induce an immune reaction. However, this seems to act against gut bacteria and favours the development of T. cruzi.
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Esta segunda edición de Medios auxiliares para el diagnóstico de las parasitosis intestinales tienen por objeto servir tanto de manual dirigido a los trabajadores de laboratorio y sobre el terreno en países con endemicidad, como de material didáctico para los estudiantes y las personas en formac...ión. En este documento se ofrece orientación para elegir la preparación en los diferentes métodos copromicroscópicos y la técnica de tinción principal para el diagnóstico de los parásitos intestinales (nematodos, trematodos, cestodos y protozoos). Las microfotografías presentan la apariencia y las características diagnósticas de los diferentes parásitos en las diversas preparaciones. Los medios auxiliares se elaboraron en un formato plastificado impermeable que es sólido y fácil de usar en la mesa de laboratorio. Se recomienda su uso a todos los profesionales de salud que se ocupan del diagnóstico corriente de las parasitosis intestinales.
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Taenia saginata is a zoonotic tapeworm that is of economic importance in countries where cattle are kept. The parasite is transmitted from human tapeworm carriers (taeniosis) to bovines (cysticercosis) by excretion of eggs or proglottids containing eggs into the environment via the stool. Bovines ca...n then ingest the eggs through contaminated feed or water. After ingestion, the eggs hatch and release oncospheres in the small intestines, where the oncospheres penetrate the intestinal wall to reach the blood circulation. This distributes them throughout the body, but primarily to muscle tissue, where they develop into cysticerci. For humans to become infected with T. saginata, raw or undercooked bovine meat or offal containing infective cysts must be consumed. Bovine cysticercosis has been associated with various environmental factors related to water sources, such as animals having access to surface water, flooding of pastures and proximity to wastewater sources.
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Schistosomiasis is a prevalent parasitic, neglected tropical disease (NTD) affecting over 220 million people globally, especially in sub-Saharan Africa (SSA). The pathology of this disease in terms of intestinal, liver and urinary presentations is well-known, yet its chronic effect on host genitalia... is often ignored or overlooked. Male genital schistosomiasis (MGS) is a gender-specific manifestation of urogenital schistosomiasis (UGS), associated with the presence of Schistosoma haematobium eggs and related pathologies in genitalia of men inhabiting or visiting endemic areas in SSA. Despite the first reported by Madden, the epidemiology, diagnostic testing and case management of MGS are not well-described owing to limited research and diminishing focus over several decades.
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Schistosomiasis, which is the second most important parasitic infection after malaria in terms of its socioeconomic impact, is responsible for the loss of an estimated 4.5 million disability-adjusted life years (DALYs) worldwide. Schistosomiasis, including both intestinal and urinary forms of the di...sease, occurs in 78 countries across the globe. An estimated 240 million people are infected, with more than 779 million living at risk globally. The majority of those infected and those at risk for infection live in low-income countries, and approximately 80% of the morbidity occurs in impoverished communities and households in sub-Saharan Africa. Within Uganda, 91 of the 134 districts are endemic for intestinal schistosomiasis caused by Schistosoma mansoni, and the eastern region, especially along Lake Victoria, has one of the highest S. mansoni burdens worldwide. Schistosoma haematobium is only endemic in the five districts of the Lango region in northern Uganda.
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A national faecal examination of 27 729 schoolchildren from 395 schools carried out in
2008 indicated that intestinal parasitic worms affected an estimated five million (56.8%)
children in Kenya. Existing evidence shows that worm infections lead to reduced literacy
levels due to impaired growth a...nd physical fitness.
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Schistosomiasis, also known as bilharzia, is a disease caused by parasitic worms that require two hosts: humans and certain species of snails. There are two forms of the disease, namely, intestinal schistosomiasis, caused by Schistosoma mansoni and S. japonicum, and urogenital schistosomiasis, cause...d by S. haematobium. There are less common schistosome species in some parts of the world, e.g. S. mekongi and S. intercalatum. Schistosomiasis ranks second only to malaria as the most common parasitic disease worldwide.
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Neglected tropical diseases (NTDs) are targeted for global control or elimination. Recognising that the populations most in need of medicines to target NTDs are those least able to support and sustain them financially, the pharmaceutical industry created mechanisms for donating medicines and experti...se to affected countries through partnerships with the WHO, development agencies, non-governmental organisations and philanthropic donors. In the last 30 y, companies have established programmes to donate 17 different medicines to overcome the burden of NTDs. Billions of tablets, capsules, intravenous and oral solutions have been donated, along with the manufacturing, supply chains and research necessary to support these efforts. Industry engagement has stimulated other donors to support NTDs with funds and oversight so that the ‘heath benefit’ return on investment in these programmes is truly a ‘best value in public health’. Many current donations are ‘open-ended’, promising support as long as necessary to achieve defined health targets. Extraordinary global health advances have been made in filariasis, onchocerciasis, trachoma, trypanosomiasis, leishmaniasis, schistosomiasis, intestinal parasites and others; and these advances are taking place in the context of strengthening health systems and meeting the global development goals espoused by the WHO. The pharmaceutical manufacturers, already strong collaborators in initiating or supporting these disease-targeted programmes, have committed to continuing their partnership roles in striving to meet the targets of the WHO’s new NTD roadmap to 2030.
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oil-transmitted helminth (STH) infections are among the most common infections worldwide and affect the poorest and most deprived communities.
They are transmitted by eggs present in human faeces which in turn contaminate soil in areas where sanitation is poor.
The main species that infect peopl...e are the roundworm (Ascaris lumbricoides), the whipworm (Trichuris trichiura) and the hookworms (Necator americanus and Ancylostoma duodenale).
Intestinal worms produce a wide range of symptoms including intestinal manifestations (diarrhoea, abdominal pain), general malaise and weakness. Hookworms cause chronic intestinal blood loss that result in anaemia.
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Last accessed on 05.03.2023
The major neglected tropical diseases, Taenia solium taeniosis/cysticercosis and schistosomiasis caused by Schistosoma mansoni or S. haematobium are presumed to be widely distributed in Africa. Taenia solium taeniosis/ cysticercosis has been reported as an emerging disease in different regions of Af...rica [1, 2], but currently the exact distribution remains unclear. Reported prevalences of T. solium taeniosis and cysticercosis in African countries are not extensive and are further complicated by the lack of ‘gold standard’ tests for diagnosis.
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This Manual covers all important aspects of echinococcosis, including parasite biology and life-cycles, geographic distribution and prevalence, epidemiology, clinical presentation in humans and animals, diagnosis and treatment, as well as control and prevention using newly developed tools and method...s. It also provides descriptions of important techniques and a large number of bibliographical references.
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La schistosomiase est une parasitose aiguë et chronique provoquée par des vers (trématodes) du genre Schistosoma. Au moins 249 millions de personnes ont eu besoin d’un traitement préventif en 2012. Le traitement préventif, qui doit être répété sur plusieurs années, permettra de réduire ...et de prévenir la morbidité.
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Schistosomiasis is an acute and chronic parasitic disease caused by blood flukes (trematode
worms) of the genus Schistosoma. At least 249 million people required preventive treatment in
2012. Preventive treatment, which should be repeated over a number of years, will reduce and
prevent morbidity.