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Country Profile on Yellow Fever: Argentina

World Health Organisation (WHO) (2022) C_WHO

This country profile presents a summary and analysis of Argentina's status with yellow fever. It is part of a series of profiles on this topic, each focusing on a different country in the Region of the Americas. Argentina's geographical location presents a wide territorial extension throughout diffe... more

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Recommendations for management of common childhood conditions
recommended

World Health Organization (2012)

Evidence for technical update of pocket book recommendations. Newborn conditions, dysentery, pneumonia, oxygen use and delivery, common causes of fever, severe acute malnutrition and supportive care

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The burden of asthma, hay fever and eczema in adults in 17 countries: GAN Phase I study

Mortimer, K.; Lesosky, M.; García-Marcos, L.; et al. (2022) CC2

Asthma, hay fever and eczema are three common chronic conditions. There have been no recent multi-country data on the burden of these three conditions in adults; the aims of this study are to fill this evidence gap. The Global Asthma Network Phase I is a multi-country cross-sectional population-bas... more

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Dengue Fever Pathophysiology, Symptoms, Diagnosis & Treatment

J J Medicine (2020) CC

Dengue Fever & What You Need to Know, including Pathophysiology, Symptoms, Diagnosis & Treatment. Dengue fever is a viral infection with potentially fatal consequences. In this lesson, we discuss how people are infected with Dengue fever, pathophysiology of the condition, along with phases of infect... more

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Guidelines on Clinical Management of Chikungunya Fever

World Health Organization (WHO), Regional Office for South-East Asia (2007) C_WHO

The socioeconomic factors and public health inadequacies that facilitated the rapid spread of this infection continue to exist. As it is a new and emerging disease it has not received sufficient coverage yet in the medical curricula of Member States. Specific treatment is not available, and there is... more

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What is Asthma?

National Asthma Education Programme (2012) CC2

Asthma: • is one of the most common respiratory complaints in the world today. • affects one in ten children (10%) and one in twenty adults (5%) • can occur for the first time at any age, even in adulthood. •usually begins before the age of five years. A few children affected will �... more

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Maldives National Action Plan for Containment of Antimicrobial Resistance 2017-2022

Maldives Food and Drug Authority Ministry of Health (2017) C2

Maldives has made significant strides in the area of infectious disease prevention and control. This is exemplified by elimination of malaria from Maldives in 2015 and successes in TB control. In addition, Maldives is a front runner in infectious disease prevention through successful water, sanitati... more

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Assessing health systems in Guinea for prevention and control of priority zoonotic diseases: A One Health approach

Standleya C. J., Carlinb E. P., Sorrella E. M. et al. Elsevier (2019) CC

To guide One Health capacity building efforts in the Republic of Guinea in the wake of the 2014–2016 Ebola virus disease (EVD) outbreak, we sought to identify and assess the existing systems and structures for zoonotic disease detection and control. We partnered with the government ministries resp... more

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Therapeutics and COVID-19 (Living Guideline, 10 November 2023)

World Health Organization WHO (2023) C_WHO

WHO has updated its guidelines for COVID-19 therapeutics, with revised recommendations for patients with non-severe COVID-19. This is the 13th update to these guidelines. Updated risk rates for hospital admission in patients with non-severe COVID-19 The guidance includes updated risk rates for... hospital admission in patients with non-severe COVID-19. The current COVID-19 virus variants tend to cause less severe disease while immunity levels are higher due to vaccination, leading to lower risks of severe illness and death for most patients. This update includes new baseline risk estimates for hospital admission in patients with non-severe COVID-19. The new ‘moderate risk’ category now includes people previously considered to be high risk including older people and/or those with chronic conditions, disabilities, and comorbidities of chronic disease. The updated risk estimates will assist healthcare professionals to identify individuals at high, moderate or low risk of hospital admission, and to tailor treatment according to WHO guidelines: **High: **People who are immunosuppressed remain at higher risk if they contract COVID-19, with an estimated hospitalization rate of 6%. **Moderate: **People over 65 years old, those with conditions like obesity, diabetes and/or chronic conditions including chronic obstructive pulmonary disease, kidney or liver disease, cancer, people with disabilities and those with comorbidities of chronic disease are at moderate risk, with an estimated hospitalization rate of 3%. Low: Those who are not in the high or moderate risk categories are at low risk of hospitalization (0.5%). Most people are low risk. Review of COVID-19 treatments for people with non-severe COVID-19 WHO continues to strongly recommend nirmatrelvir-ritonavir (also known by its brand name ‘Paxlovid’) for people at high-risk and moderate risk of hospitalization. The recommendations state that nirmatrelvir-ritonavir is considered the best choice for most eligible patients, given its therapeutic benefits, ease of administration and fewer concerns about potential harms. Nirmatrelvir-ritonavir was first recommended by WHO in April 2022. If nirmatrelvir-ritonavir is not available to patients at high-risk of hospitalization, WHO suggests the use of molnupiravir or remdesivir instead. WHO suggests against the use of molnupiravir and remdesivir for patients at moderate risk, judging the potential harms to outweigh the limited benefits in patients at moderate risk of hospital admission. For people at low risk of hospitalization, WHO does not recommend any antiviral therapy. Symptoms like fever and pain can continue to be managed with analgesics like paracetamol. WHO also recommends against use of a new antiviral (VV116) for patients, except in clinical trials. The update also includes a strong recommendation against the use of ivermectin for patients with non-severe COVID-19. WHO continues to advise that in patients with severe or critical COVID-19, ivermectin should only be used in clinical trials. more

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Dengue diagnostics: serious inaccuracies are likely to occur if pre-analytical conditions are not strictly followed

Campos de Meli Iani, F.; A.C. Barbosa Caetano, J.C. Wenceslau Cocovich et al. (2021) CC

Mem Inst Oswaldo Cruz . 2021 Jan 29;115:e200287. doi: 10.1590/0074-02760200287. eCollection 2021. Sensitivity and negative predictive value were directly affected by sample storage conditions. RT-PCR and virus isolation showed greater dependence on well-conserved samples for an accurate diagnosis

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WHO Informal Consultation on Fever Management in Peripheral Health Care Settings

World Health Organization (2013)

A global Review of evidence and practice

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Fever Diagnostic Technology Landscape
recommended

UNITAID World Health Organisation (WHO) (2018) C_WHO

1st edition. Unitaid’s report describes a slate of new devices that can more efficiently identify dangerously ill children so that they can be treated immediately. These tools make it easier to recognize danger signs, and support integrated approaches to reducing childhood deaths from the three ... more

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Images showing individual symptoms of Ebola: Fever

Centers for Disease Control and Prevention CDC (2014)

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Dengue detection: Advances and challenges in diagnostic technology

Subraya Hegde, S.; B. Ramachandra Bhat Biosensors and Bioelectronics: X (2022) CC

Biosensors and Bioelectronics: X Volume 10, May 2022, 100100; This article provides an overview of dengue disease, the working principles, the significance of the various conventional and biosensor detection strategies, the benefits and problematic conditions of the reported methods. The present hu... more

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Pandemic and epidemic-prone diseases

World Health Organization WHO (2017) C_WHO

The past two decades have witnessed changes in how humans live. Travel and trade, rapid urbanization, limited access to health care as well as environmental degradation and other trends all create the conditions for epidemics to thrive and grow. At the same time, the science and knowledge around inf... more

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Newborn Care Videos: The Hot Baby

Global Health Media Project (2014) CC

This film shows the baby with a high body temperature: how to examine the baby, cool the baby, and determine if the baby is sick and needs referral (or, in cases where there is no referral option, how to treat the baby). http://globalhealthmedia.org/newborn/videos/the-hot-baby/