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Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infecti...ons are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

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Inhaler Techniques - lagos acacia 2018

lagos acacia (2018) CC2

This video is meant to train the public on how to use some of the devices for delivery of asthma medications.

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Working Paper 46 - Aid, China, and Growth: Evidence from a New Global Development Finance Dataset

Dreher, A.; A. Fuchs; B. Parks et al. AidData at William & Mary (2017) CC

This paper introduces a new dataset of official financing—including foreign aid and other forms of concessional and non-concessional state financing—from China to 138 countries between 2000 and 2014. We use these data to investigate whether and to what extent Chinese aid affects economic growth ... more

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Module: Depression

World Health Organization WHO (2017) C_WHO

Overview Learning objectives • Promote respect and dignity for people with depression. • Recognize common symptoms of depression. • Know the assessment principles of depression. • Know the management principles of depression. • Perform an assessment for depression. • Use effective... more

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11 years of tracking aid to reproductive, maternal, newborn, and child health: estimates and analysis for 2003–13 from the Countdown to 2015

Grollman, C.; L. Arregoces, M. Martínez-Álvarez et al. Lancet Glob Health (2017) C1

Background:Tracking aid fl ows helps to hold donors accountable and to compare the allocation of resources in relation to health need. With the use of data reported by donors in 2015, we provided estimates of offi cial development assistance and grants from the Bill & Melinda Gates Foundation (coll... more

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Realizing Agenda 2030: Will donor dollars and country priorities align with global goals?

Sethi, T.; S. Custer; J. Turner et al. AidData at William & Mary (2017) CC

This report seeks to uncover the extent to which global goals crowd in international financing, inform domestic policy priorities, and navigate progress toward development outcomes in low- and middle-income countries (LICs and MICs). Our report: Provides a historical perspective on how ODA financin... more

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CDC-DPDx- Leishmaniasis

Division of Parasitic Diseases DPDx Center for Disease Control and Prevention CDC (2017) CC

Leishmaniasis is a vector-borne disease that is transmitted by sandflies and caused by obligate intracellular protozoa of the genus Leishmania. Human infection is caused by about 21 of 30 species that infect mammals. These include the L. donovani complex with 3 species (L. donovani, L. infantum, and... more

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Руководство по использованию цифровых технологий для обеспечения соблюдения режима приема противотуберкулезных препаратов

World Health Organization WHO (2017) C_WHO

Одним из важных применений цифрового здравоохранения в уходе за больными туберкулезом является поддержка, которую он может оказать в соблюдении режима приема лек... more

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Technical handbook for dengue surveillance, dengue outbreak prediction/detection and outbreak response (“model contingency plan”)

World Health Organization WHO; TDR Program (2017) C_WHO

The aim of this “model contingency plan” is to assist programme managers and planners in devel-oping a national, context-specific, dengue outbreak response plan in order to: (a) detect a dengue outbreak at an early stage through clearly defined and validated alarm signals; (b) precisely define w... more

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Depression and Other Common Mental Disorders
recommended

World Health Organization (WHO) (2017) C_WHO

This booklet provides latest available estimates of the prevalence of depression and other common mental disorders at the global and regional level, together with data concerning the consequences of these disorders in terms of lost health.

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Global vector control response 2017–2030

World Health Organization (WHO) (2017) C_WHO

The Global vector control response 2017–2030 (GVCR) provides a new strategy to strengthen vector control worldwide through increased capacity, improved surveillance, better coordination and integrated action across sectors and diseases.
In May 2017, the World Health Assembly adopted resolutio... more

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Donor funding health policy and systems research in low- and middle-income countries: how much, from where and to whom

Grépin, K.; Pinkstaff C.B.; Z. C. Shroff et al. Health Research Policy and Systems (2017) C1

Background: The need for sufficient and reliable funding to support health policy and systems research (HPSR) in low- and middle-income countries (LMICs) has been widely recognised. Currently, most resources to support such activities come from traditional development assistance for health (DAH) don... more

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Onchocercose - Lignes directrices pour l’arrêt de l’administration de masse de médicaments et la vérification de l’élimination de l’onchocercose humaine : critères et procédures

Organisation mondiale de la santé OMS (2017) C_WHO

Les présentes lignes directrices ont pour objet de préparer les pays d’endémie à arrêter l’AMM à l’issue du traitement, à passer à la surveillance post-thérapeutique ainsi qu’à confirmer l’interruption de la transmission à l’issue de la phase 2 et à débuter la surveillance p... more

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Progress on the prevention and control of non-communicable diseases : report of the Secretary-General - russian version

United Nations Secretary-General United Nations General Assembly (2017) C_WHO

The document, "Progress on the Prevention and Control of Non-Communicable Diseases," reports on global efforts to reduce the impact of NCDs, such as heart disease, cancer, diabetes, and chronic respiratory diseases, following the commitments made at high-level United Nations meetings. It highlights ... more

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Future and potential spending on health 2015–40: development assistance for health, and government, prepaid private, and out-of-pocket health spending in 184 countries

Global Burden of Disease Health Financing Collaborator Network Lancet (2017) C1

Background: The amount of resources, particularly prepaid resources, available for health can affect access to health care and health outcomes. Although health spending tends to increase with economic development, tremendous variation exists among health financing systems. Estimates of future spendi... more

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Proposed policy priorities for preventing obesity and diabetes in the Eastern Mediterranean Region

Alwan A., McColl K. et al. World Health Organization (WHO) (2017) C_WHO

The document "Proposed Policy Priorities for Preventing Obesity and Diabetes in the Eastern Mediterranean Region" by WHO EMRO outlines strategies to address high obesity and diabetes rates in the Eastern Mediterranean. It emphasizes population-wide actions, such as reducing fat and sugar intake, pro... more

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A System of Health Accounts 2011: Revised edition

Organisation for Economic Co-operation and Development (OECD), Eurostat and World Health Organization (WHO) OECD Publishing, Paris (2017) CC

A System of Health Accounts 2011: Revised Edition provides an updated and systematic description of the financial flows related to the consumption of health care goods and services. As demands for information increase and more countries implement and institutionalise health accounts according to the... more

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Board of Directors Report 2016-2017

Coalition for Epidemic Preparedness Innovations (CEPI) Coalition for Epidemic Preparedness Innovations (CEPI) (2017) CC

Board of Directors Report 2016-2017 of the Coalition for Epidemic Preparedness Innovations (CEPI) outlining financial information about CEPI regarding investors and accounts.

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Donor Financing of Global Mental Health, 1995—2015: An Assessment of Trends, Channels, and Alignment with the Disease Burden

Charlson, F.J.; J. Dieleman, L. Singh et al. PLOS One (2017) CC

Background: A recent report by the Institute for Health Metrics and Evaluation (IHME) highlights that mental health receives little attention despite being a major cause of disease burden. This paper extends previous assessments of development assistance for mental health (DAMH) in two significant w... more

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Community- Based Management of Acute Malnutrition (CMAM)

World Vision International (2017) C1

Community-Based Management of Acute Malnutrition (CMAM) is a decentralised community-based approach to treating acute malnutrition. Treatment is matched to the nutritional and clinical needs of the child, with the majority children receiving treatment at home using ready-to-use foods. In-patient car... more

Depression and Other Common Mental Disorders recommended

Depression and Other Common Mental Disorders
recommended