The ZIKA TOOLBOX compiles high-quality documents and gudelines relevant for health care professionals and the general public. The documents are available in English, French, Spanish, Portuguese and German.

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This document provides interim recommendations for the surveillance of Zika virus infection, microcephaly and Guillain-Barré syndrome, in four different contexts and describes reporting requirements to WHO. Transmission refers to vector-borne transmission, unless specified differently. Autochthonou... more
La récente augmentation du nombre de cas de microcéphalie et d’autres troubles neurologiques potentiellement associés à une infection à virus Zika a engendré une recrudescence des demandes de dépistage en laboratoire de cette infection. Les groupes prioritaires pour un test de diagnostic d... more
O recente aumento dos casos de microcefalia e outras patologias neurológicas potencialmente associadas à infecção pelo vírus Zika provocou um aumento da procura de testes laboratoriais para detectar a infecção. Os grupos prioritários para os testes de diagnóstico devem ser indivíduos sin... more
published online April 13, 2016, DOI: 10.1056/NEJMsr1604338. Please download directly from the webpage: http://www.nejm.org/doi/pdf/10.1056/NEJMsr1604338
Clinician Outreach and Communication Activity (COCA) Call April 12, 2016
This document aims to present an algorithm for deciding whom to test and provide guidance on the laboratory tests for Zika virus infection diagnosis in order to support clinical diagnostic and case reporting through surveillance among EU Member States. The algorithm is not intended for clinical man... more
"Our findings provide a quantitative estimate of the risk of microcephaly in fetuses and neonates whose mothers are infected with Zika virus." Published Online: 15 March 2016, http://dx.doi.org/10.1016/S0140-6736(16)00651-6 Please download this article directly from the webpage: http://www.thela... more
For national authorities and health care practitioners
El reciente aumento de los casos de microcefalia y de otros trastornos neurológicos posiblemente asociados a la infección por el virus de Zika ha provocado un aumento de la demanda de pruebas de laboratorio para detectar dicha infección. Los grupos prioritarios para la realización de pruebas di... more
The threat posed by Zika virus infection highlights the need to reinforce preparedness arrangements for mosquito-borne diseases in EU/EEA countries, especially for pathogens transmitted by Aedes aegypti and Aedes albopictus. The aim of this document is to highlight measures that can effectively red... more
Review article published online March 30, 2016, DOI: 10.1056/NEJMra1602113. Please download directly from the webpage: http://www.nejm.org/doi/pdf/10.1056/NEJMra1602113
PAHO has systematically identified and collected basic information on all investigations related to Zika, both those already published and those on track to be published. Each study has been categorized in the areas of virus, vectors and reservoirs; epidemiology; disease pathogenesis and consequen... more