Le paludisme, maladie parasitaire causée par le Plasmodium et transmise par les moustiques Anopheles, reste la première endémie parasitaire mondiale. Malgré une baisse significative de l’incidence et de la mortalité entre 2000 et 2013, grâce aux moustiquaires, aux traitements ACT et aux test...s rapides, la maladie continue de représenter un lourd fardeau pour les pays d’endémie, en particulier en Afrique subsaharienne. En 2013, on estimait encore à 198 millions le nombre de cas et à 584 000 le nombre de décès, principalement touchant les jeunes enfants. La lutte contre le paludisme est un objectif majeur de santé publique mondiale, soutenu notamment par le Fonds mondial. Le paludisme représente aussi un risque non négligeable pour les voyageurs, avec plus de 4 000 cas d’importation en France en 2014. L’absence de vaccin efficace et l’augmentation des résistances rendent la prévention de plus en plus difficile.
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This document outlines the best practices for mosquito control and surveillance in United Nations duty stations affected by mosquito-borne diseases. It sets out an integrated vector management (IVM) approach combining environmental, biological, mechanical, chemical and personal protection strategies... to reduce mosquito populations and the transmission of diseases. Key elements include targeted control of larval and adult mosquitoes, the proper use of insecticides, community engagement, and ongoing surveillance.
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The framework recommends expanded coverage of malaria diagnostic and treatment services, intensified vector control to drive down transmission, strengthened malaria surveillance, and increased transborder collaboration, especially in terms of efforts to control the sale and use of artemisinin monoth...erapies. Since it is unlikely that national malaria control programs will be able to implement all the activities described in this framework simultaneously, a list of suggested priority activities has been included in the Annex.
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The 'Malaria Comic Book' is an educational resource designed to raise awareness of malaria prevention in India. Using a comic book format, it aims to engage readers by illustrating key information about how malaria is transmitted, its symptoms, and how to prevent it. The content is tailored to the l...ocal context, incorporating culturally relevant visuals and language to communicate health messages effectively. This approach aims to improve understanding and encourage proactive health behaviours within the community.
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This comic book is a children-friendly tool to support school safety, to raise awareness and protect communities against malaria. The comic is available in English, Khmer, Lao, Burmese and Vietnamese
Cette vidéo éducative explique le cycle de vie du parasite Plasmodium, responsable du paludisme. Transmis par la piqûre de la femelle du moustique Anopheles, le parasite infecte d'abord le foie, puis les globules rouges, provoquant des symptômes typiques tels que des frissons, de la fièvre et d...es sueurs.
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La Stratégie intégrée de communication pour la lutte contre le paludisme au Sénégal (2016) vise à renforcer la prévention et la prise en charge du paludisme par des actions de communication efficaces. Elle combine plaidoyer, mobilisation sociale et communication pour le changement de comporte...ment afin d’augmenter l’utilisation des moustiquaires imprégnées, le recours au traitement précoce, la chimio-prévention saisonnière et l’aspersion intradomiciliaire. Le document définit les objectifs, les messages clés, les cibles, les canaux de communication (comme la radio, la télévision, les activités communautaires) et les mécanismes de suivi-évaluation. L’accent est mis sur la coordination nationale et locale pour harmoniser les actions, renforcer l’adhésion des communautés et garantir un impact durable sur la santé publique au Sénégal.
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(version 1.0): procedure: methods manual
Prévention et prise en charge du paludisme.
Dans le cadre stratégique 2014-2018, le Sénégal s’est fixé comme objectif l’accélération du contrôle du paludisme en vue de sa pré-élimination. L’atteinte de cet objectif passera nécessairement par une couverture universelle pour toute...s les interventions de prise en charge et de prévention.
Ces interventions intéressent essentiellement les axes stratégiques que sont la lutte anti vectorielle, le paludisme et grossesse, la chimio prévention saisonnière, la prise en charge des cas, la gestion des épidémies et des urgences, la gestion des approvisionnements et des stocks, la promotion de la santé, le suivi évaluation et la gestion du programme.
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Ce manuel présente des informations essentielles sur l’épidémiologie du paludisme, les aspects de prévention et de prise en charge du paludisme mais aussi les interventions de soutien.
Il sert à la formation en cours d’emploi des médecins, des sages-femmes, des infirmiers, et autres agent...s de santé prenant en charge le paludisme.
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BMC Medicine (2015) 13:42 DOI 10.1186/s12916-014-0263-6
The Strategic Malaria Communication Guide for Central America is intended to facilitate the shift from malaria control to elimination by strengthening communication and advocacy initiatives throughout the region. Based on interviews and a review of literature, the guide offers National Malaria Progr...ammes (NMPs) recommendations on messaging, target audiences, communication channels and advocacy strategies. The guide's primary goals are to raise awareness of malaria elimination, encourage long-term commitment from decision-makers and mobilise sustainable resources. The guide outlines two strategic objectives: (1) creating a shared understanding of the long-term requirements for malaria elimination, including funding, surveillance and multi-sectoral engagement, and (2) expanding support among public, private and cross-sectoral stakeholders. With malaria cases having already reduced by 88% since 2000, the guide emphasises the importance of maintaining focus and investment in order to fully eliminate the disease and prevent its re-establishment in Central America.
Accessed on 10/06/2025.
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This Communication Guide for Malaria Control Interventions is aligned with Tanzania’s Malaria Strategic Plan (2015–2020) and provides comprehensive guidance on the implementation of Social and Behaviour Change Communication (SBCC) for the prevention, diagnosis and treatment of malaria. It is int...ended for all stakeholders and implementing partners, with the aim of ensuring harmonised messaging and coordinated communication efforts. The guide outlines strategies, key messages, communication channels and target audiences, with a focus on sustaining and improving malaria-related behaviours at the individual, family and community levels. It incorporates malaria stratification and supports the development of tailored SBCC interventions in different risk areas. Developed with contributions from the Ministry of Health and Social Welfare, the National Malaria Control Programme and various partner organisations, the guide aims to reduce the malaria burden and promote a malaria-free Tanzania. Supplemented by Standard Operating Procedures (SOPs), the guide serves as a practical tool for consistent and effective malaria communication nationwide.
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Vector control, alongside case management, remains the most effective approach to controlling and eliminating malaria. Key interventions, such as indoor residual spraying (IRS) and long-lasting insecticidal nets (LLINs), have significantly reduced malaria transmission in many African countries. This... has enabled some countries to transition from the control phase to the elimination phase.
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Antimalarial chemotherapy is crucial for reducing morbidity, mortality, and drug resistance, and is the cornerstone of malaria control. Existing antimalarial drugs act at different stages of the parasite’s life cycle. These drugs range from classic agents such as chloroquine and quinine to newer a...rtemisinin derivatives. They include tissue schizonticides, blood schizonticides, gametocytocides, and sporontocides. Artemisinin and its derivatives are the most effective and fastest-acting treatment against drug-resistant Plasmodium falciparum, achieving rapid parasite clearance and reducing transmission potential. Other key drugs include mefloquine, halofantrine, proguanil, sulfadoxine–pyrimethamine, atovaquone–proguanil, tetracyclines, clindamycin and azithromycin. Each of these drugs has a specific mechanism of action, pharmacokinetics, efficacy, safety profile and contraindications. Rational drug combinations and adherence to national treatment guidelines are essential for managing resistance, ensuring safety in vulnerable populations such as children and pregnant women, and optimising therapeutic outcomes in cases of both uncomplicated and severe malaria.
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Combination therapy is a cornerstone of modern malaria treatment, particularly in the context of widespread multidrug resistance. Using two or more antimalarial drugs with different mechanisms simultaneously enhances efficacy, shortens treatment duration, improves compliance and delays the developme...nt of resistance. Artemisinin-based combination therapies (ACTs), such as artemether–lumefantrine, artesunate–amodiaquine and artesunate–sulfadoxine/pyrimethamine, are highly effective in rapidly clearing parasites and reducing gametocyte carriage. They are also generally well tolerated. Non-artemisinin combinations, quinine-based regimens and novel combinations (e.g. piperaquine–dihydroartemisinin) offer alternative therapeutic options, although clinical experience with these remains limited. Although ACTs are the preferred first-line treatment, factors such as cost, local drug resistance patterns, safety during pregnancy and paediatric use must inform implementation and policy decisions.
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