Cryptococcal disease is one of the most common opportunistic infections among people living with advanced HIV disease and is a major contributor to severe illness, morbidity, and mortality, particularly in sub-Saharan Africa.
These guidelines update the recommendations that were first released i...n 2018 on diagnosing, preventing, and managing cryptococcal disease. In response to important new evidence that became available in 2021, these new guidelines strongly recommend a single high dose of liposomal amphotericin B as part of the preferred induction regimen for the treatment of cryptococcal meningitis in people living with HIV. This simplified regimen - a single high dose of liposomal amphotericin B paired with other standard medicines (flucytosine and fluconazole) - is as effective as the previous WHO standard of care, with the benefits of lower toxicity and fewer monitoring demands.
The objective of these guidelines is to provide updated, evidence-informed recommendations for treating adults, adolescents and children living with HIV who have cryptococcal disease. These guidelines are aimed at HIV programme managers, policymakers, national treatment advisory boards, implementing partners and health-care professionals providing care for people living with HIV in resource-limited settings with a high burden of cryptococcal disease.
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Biennial Report of the Regional Director
This policy brief is targeted at national governments, donors and regional and international actors to support Ebola-affected countries to transition from emergency response to recovery.
The handbook is the first comprehensive collection of practical tips for journalists on how to report on GBV in the context of Syria crisis, building upon internationally recognised ethical principles. It gives an overview of techniques to guarantee the safety, confidentiality and dignity of survivo...rs, their families and communities. It includes terms, ethical questions and practical concerns associated with covering GBV, as well as an overview of some of the organisations involved in both combatting GBV and providing support services for survivors.
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Towards the Elimination of Mother-to-Child Transmission of HIV and keeping mothers Alive. 2012-2015
National estimates have been developed every two years since 2003, led by the NCASC with close collaboration from a range of technical experts, partners and epidemiologists from the UNAIDS, WHO and FHI. This contains information about estimations of adult HIV prevalence.
National Tuberclosis and
Leprosy Programme (NTLP)
Euro Surveill. 2015 Mar 26;20(12). pii: 21073.
Confernece Report 15-16 April 2013 - Dublin, Ireland
The Regional strategy for measles control recommends that a second opportunity for measles immunization be provided to all children irrespective of their vaccination status or history of clinical measles. The preferred method of provision of a second opportunity is through Supplemental Immunization ...Activities (SIAs) targeting children 9 months to 14 years in catch-up campaigns and 9 months to 4 or 5 years during periodic follow-up campaigns
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For each medicine the Formulary provides information on use, dosage, adverse effects, contraindications and warnings, supplemented by guidance on selecting the right medicine for a range of conditions