MEDBOX | category General Guidelines

Foundation for Innovative and New Diagnostics (2020) C2

FIND conducted independent evaluations at the University Hospitals of Geneva (HUG), to verify the limit of detection (LOD) and the clinical performance (as reported by the manufacturers) of the following molecular test kits. The LOD analysis was performed using cultured viral stocks from a clinical isolate from Switzerland, and quantified using an E gene standard. The clinical performance analysis was conducted on extracted samples from individuals suspected to have COVID-19 that were tested using an in-house PCR protocol that was optimized based on the Tib Molbiol assay

Tags: SARS-CoV-2, Laboratory diagnostics, molecular testing,

Source: https://www.finddx.org/covid-19/sarscov2

Second WHO Model List of Essential In Vitro Diagnostics

World Health Organization WHO (2019) C_WHO

The updated List of Essential Diagnostics contains 46 general tests that can be used for routine patient care as well as for the detection and diagnosis of a wide array of disease conditions, and 69 tests intended for the detection, diagnosis and monitoring of specific diseases. The List is divided into two sections depending on the user and setting: one for community settings, which includes self-testing; and a second one for clinical laboratories, which can be general and specialized facilities

Tags: essential list, Essential Medicine, laboratory, diagnostic, Laboratory diagnostics, WHO guidelines, essential medicines list, medical devices,

Source: https://www.who.int/medical_devices/publ

Guidelines for the Structure of Public Health Entomology Laboratories

Pan American Health Organization (PAHO) (2019) C_WHO

This document provides countries with recommendations for structuring a public health entomology laboratory network. The document will help countries to identify their areas of need and determine how the entomology network can be strengthened, especially in the context of a decentralized health system. The recommendations also consider the different degrees of development and different entomological research needed to support disease prevention and control activities

Tags: vector-borne diseases, Zika, chikungunya, entomology, Disease Prevention & Control, laboratory, Surveillance,

Source: http://iris.paho.org/xmlui/bitstream/han

Orientaciones para la estructuración de laboratorios de entomología en salud pública

Pan American Health Organization (PAHO) (2019) C_WHO

El documento ayudará a los países a identificar las áreas de necesidades y determinar cómo se puede reforzar la red de entomología, especialmente en el contexto de un sistema de salud descentralizado. Las recomendaciones también tienen en cuenta los diferentes grados de desarrollo y las diferentes investigaciones entomológicas necesarias para dar soporte a las acciones de prevención y control de las enfermedades

Tags: laboratórios, entomologicá, salud pública, bioseguridad, dengue, Zika, chikungunya, malaria, Leishmaniasis, control de vectores,

Source: http://iris.paho.org/xmlui/handle/123456

WHO manual for organizing a national external quality assessment programme for health laboratories and other testing sites

World Health Organization WHO (2016) C_WHO

This manual describes some of the strategic, managerial, financial, technical and scientific aspects to be considered in establishing a national EQA programme for clinical laboratories and other testing services at all health care level

Tags: laboratory, laboratory management, Quality Control, Quality assurance, Quality Management, Testing,

Source: http://apps.who.int/iris/bitstream/10665

World Health Organization ( WHO), Regional Office for South-East-Asia (2016) C_WHO

Polymerase Chain Reaction (‎PCR)‎ has significantly helped in early diagnosis and commencement of specific interventions for diseases control. It also plays a critical role in understanding the disease epidemiology and unraveling the transmission dynamics of the disease. This manual intends to provide primary guidelines to assist health lab personnel in developing countries to establish a PCR diagnostic facility for efficient support to patient care as well as public health actions

Tags: Polymerase Chain Reaction (PCR), disease control, laboratoires, clinical protocol, developing countries, diagnostics, Guidelines,

Source: http://apps.searo.who.int/PDS_DOCS/B5256

World Health Organization WHO; Centers for Disease Control and Prevention CDC; Clinical and Laboratory Standards Institute (CLSI) (2015) C_WHO

Training laboratory managers, senior biologists, and technologists in quality management systems is a step towards obtaining international recognition; it is a step that all countries should take. This training toolkit is intended to provide comprehensive materials that will allow for designing and organizing training workshops for all stakeholders in health laboratory processes, from management, to administration, to bench-work laboratorian

Tags: Quality Management, Quality Control, Training, laboratory, Laboratory diagnostics, Laboratory Performance,

Source: http://www.who.int/ihr/training/laborato

Laboratory Assessment Tool user survey

World Health Organization (2015) C_WHO

Laboratory Assessment Tool user survey now online! After 3 years in use, the Health Laboratory Strengthening Team is conducting a review to determine how the tool has been used and learn from users what are its strengths and weaknesses. This review will serve as the basis for a potential revision of the Tool and publication of an improved version

Tags: laboratory,

Source: https://extranet.who.int/dataform/128315

Laboratory issues for epidemiologists

World Health Organization WHO (2015) C_WHO

The main objectives of the training module - facilitate communication and understanding between the two disciplines of epidemiology and laboratory (medicine) for disease surveillance and outbreak investigation; - provide the field epidemiologist with a better understanding of basic microbiology techniques and analysis and interpretation of results; - convey the laboratory perspective of public health investigations to field epidemiologists in order to improve collaboration between these two disciplines and to enhance

Tags: Surveillance, laboratory, Epidemiology,

Source: http://www.who.int/ihr/lyon/surveillance

Guidance on regulations for the Transport of Infectious Substances 2015-2016

World Health Organization (2015) C_WHO

This publication provides information for identifying, classifying, marking, labelling, packaging, documenting and refrigerating infectious substances for transportation and ensuring their safe delivery. The document provides practical guidance to facilitate compliance with applicable international regulations for the transport of infectious substances by all modes of transport, both nationally and internationally, and include the changes that apply from 1 January 2015. The current revision replaces the document issued by the World Health Organization (WHO) in 2012 (document WHO/CDS/EPR/2012.12). This publication, however, does not replace national and international transport regulations

Source: http://apps.who.int/iris/bitstream/10665

	SARS-CoV-2 molecular assay evaluation: results Foundation for Innovative and New Diagnostics (2020) C2 Open external link (250) Add to my MEDBOX FIND conducted independent evaluations at the University Hospitals of Geneva (HUG), to verify the limit of detection (LOD) and the clinical performance (as reported by the manufacturers) of the following molecular test kits. The LOD analysis was performed using cultured viral stocks from a clinical isolate from Switzerland, and quantified using an E gene standard. The clinical performance analysis was conducted on extracted samples from individuals suspected to have COVID-19 that were tested using an in-house PCR protocol that was optimized based on the Tib Molbiol assay Tags: SARS-CoV-2, Laboratory diagnostics, molecular testing, Source: https://www.finddx.org/covid-19/sarscov2
	Second WHO Model List of Essential In Vitro Diagnostics World Health Organization WHO (2019) C_WHO View PDF(336) Download (256) Add to my MEDBOX The updated List of Essential Diagnostics contains 46 general tests that can be used for routine patient care as well as for the detection and diagnosis of a wide array of disease conditions, and 69 tests intended for the detection, diagnosis and monitoring of specific diseases. The List is divided into two sections depending on the user and setting: one for community settings, which includes self-testing; and a second one for clinical laboratories, which can be general and specialized facilities Tags: essential list, Essential Medicine, laboratory, diagnostic, Laboratory diagnostics, WHO guidelines, essential medicines list, medical devices, Source: https://www.who.int/medical_devices/publ
	Guidelines for the Structure of Public Health Entomology Laboratories Pan American Health Organization (PAHO) (2019) C_WHO View PDF(23) Download (32) Add to my MEDBOX This document provides countries with recommendations for structuring a public health entomology laboratory network. The document will help countries to identify their areas of need and determine how the entomology network can be strengthened, especially in the context of a decentralized health system. The recommendations also consider the different degrees of development and different entomological research needed to support disease prevention and control activities Tags: vector-borne diseases, Zika, chikungunya, entomology, Disease Prevention & Control, laboratory, Surveillance, Source: http://iris.paho.org/xmlui/bitstream/han
	Orientaciones para la estructuración de laboratorios de entomología en salud pública Pan American Health Organization (PAHO) (2019) C_WHO View PDF(24) Download (24) Add to my MEDBOX El documento ayudará a los países a identificar las áreas de necesidades y determinar cómo se puede reforzar la red de entomología, especialmente en el contexto de un sistema de salud descentralizado. Las recomendaciones también tienen en cuenta los diferentes grados de desarrollo y las diferentes investigaciones entomológicas necesarias para dar soporte a las acciones de prevención y control de las enfermedades Tags: laboratórios, entomologicá, salud pública, bioseguridad, dengue, Zika, chikungunya, malaria, Leishmaniasis, control de vectores, Source: http://iris.paho.org/xmlui/handle/123456
	WHO manual for organizing a national external quality assessment programme for health laboratories and other testing sites World Health Organization WHO (2016) C_WHO View PDF(1175) Download (540) Add to my MEDBOX This manual describes some of the strategic, managerial, financial, technical and scientific aspects to be considered in establishing a national EQA programme for clinical laboratories and other testing services at all health care level Tags: laboratory, laboratory management, Quality Control, Quality assurance, Quality Management, Testing, Source: http://apps.who.int/iris/bitstream/10665
	Establishment of PCR laboratory in developing countries, 2nd ed. World Health Organization ( WHO), Regional Office for South-East-Asia (2016) C_WHO View PDF(580) Download (293) Add to my MEDBOX Polymerase Chain Reaction (‎PCR)‎ has significantly helped in early diagnosis and commencement of specific interventions for diseases control. It also plays a critical role in understanding the disease epidemiology and unraveling the transmission dynamics of the disease. This manual intends to provide primary guidelines to assist health lab personnel in developing countries to establish a PCR diagnostic facility for efficient support to patient care as well as public health actions Tags: Polymerase Chain Reaction (PCR), disease control, laboratoires, clinical protocol, developing countries, diagnostics, Guidelines, Source: http://apps.searo.who.int/PDS_DOCS/B5256
	Laboratory quality management system training toolkit World Health Organization WHO; Centers for Disease Control and Prevention CDC; Clinical and Laboratory Standards Institute (CLSI) (2015) C_WHO Open external link (1825) Add to my MEDBOX Training laboratory managers, senior biologists, and technologists in quality management systems is a step towards obtaining international recognition; it is a step that all countries should take. This training toolkit is intended to provide comprehensive materials that will allow for designing and organizing training workshops for all stakeholders in health laboratory processes, from management, to administration, to bench-work laboratorian Tags: Quality Management, Quality Control, Training, laboratory, Laboratory diagnostics, Laboratory Performance, Source: http://www.who.int/ihr/training/laborato
	Laboratory Assessment Tool user survey World Health Organization (2015) C_WHO Open external link (1118) Add to my MEDBOX Laboratory Assessment Tool user survey now online! After 3 years in use, the Health Laboratory Strengthening Team is conducting a review to determine how the tool has been used and learn from users what are its strengths and weaknesses. This review will serve as the basis for a potential revision of the Tool and publication of an improved version Tags: laboratory, Source: https://extranet.who.int/dataform/128315
	Laboratory issues for epidemiologists World Health Organization WHO (2015) C_WHO Open external link (1256) Add to my MEDBOX The main objectives of the training module - facilitate communication and understanding between the two disciplines of epidemiology and laboratory (medicine) for disease surveillance and outbreak investigation; - provide the field epidemiologist with a better understanding of basic microbiology techniques and analysis and interpretation of results; - convey the laboratory perspective of public health investigations to field epidemiologists in order to improve collaboration between these two disciplines and to enhance Tags: Surveillance, laboratory, Epidemiology, Source: http://www.who.int/ihr/lyon/surveillance
	Guidance on regulations for the Transport of Infectious Substances 2015-2016 World Health Organization (2015) C_WHO View PDF(2186) Download (1081) Add to my MEDBOX This publication provides information for identifying, classifying, marking, labelling, packaging, documenting and refrigerating infectious substances for transportation and ensuring their safe delivery. The document provides practical guidance to facilitate compliance with applicable international regulations for the transport of infectious substances by all modes of transport, both nationally and internationally, and include the changes that apply from 1 January 2015. The current revision replaces the document issued by the World Health Organization (WHO) in 2012 (document WHO/CDS/EPR/2012.12). This publication, however, does not replace national and international transport regulations Source: http://apps.who.int/iris/bitstream/10665

SARS-CoV-2 molecular assay evaluation: results (2020)

Establishment of PCR laboratory in developing countries, 2nd ed. (2016)

Laboratory quality management system training toolkit (2015)

District Laboratory Practice in Tropical Countries Part 1 (2009)

District Laboratory Practice in Tropical Countries Part-2 (2006)

SARS-CoV-2 molecular assay evaluation: results (2020)

Second WHO Model List of Essential In Vitro Diagnostics (2019)

Guidelines for the Structure of Public Health Entomology Laboratories (2019)

Orientaciones para la estructuración de laboratorios de entomología en salud pública (2019)

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MEDBOX Video Series

SARS-CoV-2 molecular assay evaluation: results (2020)

Establishment of PCR laboratory in developing countries, 2nd ed. (2016)

Laboratory quality management system training toolkit (2015)

District Laboratory Practice in Tropical Countries Part 1 (2009)

District Laboratory Practice in Tropical Countries Part-2 (2006)

SARS-CoV-2 molecular assay evaluation: results (2020)

Second WHO Model List of Essential In Vitro Diagnostics (2019)

Guidelines for the Structure of Public Health Entomology Laboratories (2019)

Orientaciones para la estructuración de laboratorios de entomología en salud pública (2019)