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Malaria and HIV, two of the world’s most deadly diseases, are widespread, but their distribution overlaps greatly in sub-Saharan Africa. Consequently, malaria and HIV coinfection (MHC) is common in the region. In this paper, pertinent publications on the prevalence, impact, and treatment strategie
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s of MHC obtained by searching major electronic databases (PubMed, PubMed Central, Google Scholar, ScienceDirect, and Scopus) were reviewed, and it was found that the prevalence of MHC in SSA was 0.7%–47.5% overall. Prevalence was 0.7%–47.5% in nonpregnant adults, 1.2%–27.8% in children, and 0.94%–37% in pregnant women. MHC was associated with an increased frequency of clinical parasitemia and severe malaria, increased parasite and viral load, and impaired immunity to malaria in nonpregnant adults, children, and pregnant women, increased in placental malaria and related outcomes in pregnant women, and impaired antimalarial drug efficacy in nonpregnant adults and pregnant women. Although a few cases of adverse events have been reported in coinfected patients receiving antimalarial and antiretroviral drugs concurrently, available data are very limited and have not prompted major revision in treatment guidelines for both diseases. Artemisinin-based combination therapy and cotrimoxazole are currently the recommended drugs for treatment and prevention of malaria in HIV-infected children and adults. However, concurrent administration of cotrimoxazole and sulfadoxine–pyrimethamine in HIV-infected pregnant women is not recommended, because of high risk of sulfonamide toxicity. Further research is needed to enhance our understanding of the impact of malaria on HIV, drug–drug interactions in patients receiving antimalarials and antiretroviral drugs concomitantly, and the development of newer, safer, and more cost-effective drugs and vaccines to prevent malaria in HIV-infected pregnant women.
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The document provides a standardized protocol for evaluating the Early Warning Alert and Response Network (EWARN), a surveillance system used during humanitarian emergencies when regular national health surveillance may be disrupted. The purpose of EWARN is to detect outbreaks of communicable diseas
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es early and enable rapid public health response. The guidance explains how the system should be assessed in terms of its structure, implementation, effectiveness, and usefulness. It outlines the key steps of evaluation: preparation, system description, data collection, and post-evaluation reporting. The protocol highlights common challenges observed in previous EWARN implementations, such as delays in establishing the system, limited data quality, weak outbreak response, and lack of clear transition plans back to routine surveillance systems. It emphasizes the need to evaluate both weekly disease reporting and alert verification processes, and to review attributes such as simplicity, data quality, timeliness, sensitivity, and stability. The document also provides templates for interviews, data review forms, and laboratory assessment, as well as guidance on conducting remote evaluations when access is limited. The overall goal of the protocol is to ensure that EWARN functions effectively to detect and respond to outbreaks and that practical recommendations are developed to improve the system’s performance and sustainability in emergency settings.
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Continuum of HIV services refers to a comprehensive package of HIV prevention, diagnostic, treatment, care and support services provided for people at risk of infection or living with HIV and their families. This revised edition of the guidelines for use of ARV and opportunistic infection
(OI) dru
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gs in adults, adolescents and children is based on recent national and
global evidences and experiences. The Federal Ministry of Health believes that
these guidelines, along with other national guidelines and training manuals, will be
instrumental in maintaining the standard of care and ensuring quality of HIV service
delivery.
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National SOP document from Eswatini for community-based models for HIV testing and ART initiation. Contains specific procedural steps for testing and ART initiation in mobile/outreach contexts – very practical for clinical SOP structures in similar settings.
This booklet is aimed at HCP’s, and serves to raise awareness, and emphasize the need for
the inclusion and integration of psychosocial support in the Comprehensive HIV and AIDS
Care, Management and Treatment (CCMT) of children and adolescents.
World Health Organization (2018). A practical guide for developing and conducting simulation exercises to test and validate pandemic influenza preparedness plans.
World Health Organization (2018). A practical guide for developing and conducting simulation exercises to test and validate pandemic influenza preparedness plans. World Health Organization.
World Health Organization (2018). A practical guide for developing and conducting simulation exercises to test and validate pandemic influenza preparedness plans. World Health Organization.
Всемирная организация здравоохранения (2018). Практическое руководство по разработке и проведению имитационных учений в целях проверки и подтверждения планов обес
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ечения готовности к пандемическому гриппу. Всемирная организация здравоохранения.
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Organización Mundial de la Salud (2019). Guía práctica para la preparación y ejecución de ejercicios de simulación destinados a poner a prueba y validar los planes de preparación ante la gripe pandémica. Organización Mundial de la Salud.
Organisation mondiale de la Santé (2019). Guide pratique pour l’élaboration et la conduite d’exercices de simulation destinés à tester et à valider les plans de préparation à la grippe pandémique. Organisation mondiale de la Santé.
Caja de herramientos para educadoras y educadores de Centros de Desarollo Infantil
Caja de herramientas para educadoras y educadores de Centro de Desarollo Infantil
Caja de herramientas para educadoras y educadores de Cemtros de Desarollo Infantil
Caja de herramientas para educadoras y educadores de Centros de Desarollo Infantil
Caja de herramientas para educadoras y educadores de Centros de Desarollo Infantil
Orientaciones y Procedimientos
Juego en los centros de Desarolllo Infantil
This document provides standard operating procedures (SOPs) for infection prevention and control (IPC) when managing Ebola Virus Disease (EVD) cases in healthcare settings in Tanzania. It outlines standardized procedures for patient screening, isolation, use of personal protective equipment (PPE), h
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and hygiene, environmental cleaning and disinfection, waste management, safe handling of specimens, and protection of healthcare workers. The SOP aims to strengthen preparedness, reduce the risk of Ebola transmission, and ensure a safe and consistent response during Ebola outbreaks.
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