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Q 1: Are antidepressants (Tricyclic Antidepressants (TCA) and Selective Serotonin Reuptake Inhibitors (SSRI)) better (more
effective than/as safe as) than treatment as usual (placebo) in adults with depressive episode/disorder?
Q10: Are antidepressants (Tricyclic antidepressants (TCA), Selective serotonin reuptake inhibitors (SSRIs)) effective and safe in children 6-12 years of age with depressive episode/disorder?
(2015)
Scoping question: Are antidepressants (specifically, tricyclic antidepressants and selective serotonin reuptake inhibitors) effective and safe in adolescents with moderate-severe depressive disorder for whom psychosocial interventions have proven ineffective?
Abstract: Posttraumatic stress disorder (PTSD) is a chronic psychological disorder that can develop after exposure to a traumatic event. This review summarizes the literature on the epidemiology, assessment, and treatment of PTSD. We provide a review of the characteristics of PTSD along with associa...
Anxiety disorders
Chapter F.5
WHO Model Formulary
recommended
For each medicine the Formulary provides information on use, dosage, adverse effects, contraindications and warnings, supplemented by guidance on selecting the right medicine for a range of conditions
This twelfth version of the WHO living guideline now contains 19 recommendations. This latest update provides updated recommendations for remdesivir, addresses the use of combination therapy with corticosteroids, interleukin-6 (IL-6) receptor blockers and Janus kinase (JAK) inhibitors in patients wi...
Dialogues Clin Neurosci. 2017 Jun; 19(2): 93–107.
An Evidence-Based Treatment Guide for Clinicians
Q 2: How long should treatment with antidepressants continue in adults with depressive episode/disorder?
International Journal of Psychiatry in Clinical Practice, 2012; 16: 77–84
Sci Rep. 2016; 6: 25920. Published online 2016 May 16. doi: 10.1038/srep25920
Occasional anxiety is a normal part
of life. You might worry about things
like health, money, or family
problems. But people with
generalized anxiety disorder (GAD)
feel extremely worried or feel
nervous about these and other
things—even when there is little or
no reason to worry about the...
Post-Traumatic Stress Disorder (PTSD) in children and adolescents occurs when a child is exposed to one or more events that are unexpected, uncontrollable, life-threatening, and likely to cause serious harm or injury to himself/herself or someone significantly important to the child. In response, th...
WHO guidelines on the pharmacological treatment of persisting pain in children with medical illnesses
As part of the Mental Health Gap Action Programme, WHO has developed training manuals (Training of trainers and supervisors training manual and Training of health-care providers training manual) to support implementation of the mhGAP Intervention Guide for mental, neurological and substance use (MNS...
Do you sometimes have sudden attacks of
anxiety and overwhelming fear that last for
several minutes? Maybe your heart pounds,
you sweat, and you feel like you can’t
breathe or think. Do these attacks occur at
unpredictable times with no obvious trigger,
causing you to worry about the possibi...
Standard Treatment Guideline
Q4: For people with dementia with associated depression, do antidepressants when compared to placebo/comparator produce benefits/harm in the specified outcomes?
