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The growing understanding of how sequence information can contribute to improved public health is driving global investments in sequencing facilities and programmes. The falling cost and complexity of generating GSD provides opportunities for expanding sequencing capacity; however, challenges to wid... more
8 January 2021 Sequencing enabled the world to rapidly identify SARS-CoV-2 and develop diagnostic tests and other tools for outbreak management. Continued genome sequencing supports the monitoring of the disease’s spread and evolution of the virus. Accelerated integration of genome sequencing int... more
The growing understanding of how sequence information can contribute to improved public health is driving global investments in sequencing facilities and programmes. The falling cost and complexity of generating GSD provides opportunities for expanding sequencing capacity; however, challenges to wid... more
Genomic sequencing has been an essential tool in generating virological data, driving the laboratory response, and better understanding the dispersal and evolutionary patterns of SARS-CoV-2. In addition to the characterization of the global circulation patterns, early detection of SARS-CoV-2 variant... more
15 July 2021
The Strategy provides a high-level unifying framework to leverage existing capacities, address barriers and strengthen the use of genomic surveillance in the detection, monitoring and response to public health threats. Genomic surveillance is part of the broader surveillance and laboratory system, a... more
Whole-genome sequencing (WGS) provides a vast amount of information and the highest possible resolution for pathogen subtyping. The application of WGS for global surveillance can provide information on the early emergence and spread of AMR and further inform timely policy development on AMR control.... more
Pathogen genomic surveillance has become a priority for public health systems in recent years. Genomic sequencing is increasingly being used to characterize pathogens and monitor important public health priorities (e.g. poliovirus, influenza virus, Mycobacterium tuberculosis and Vibrio cholerae, ant... more
Au cours de la dernière décennie, les données de séquençage génétique des agents pathogènes ont gagné en importance et contribuent désormais de façon déterminante à la détection et à la maîtrise des flambées de maladies infectieuses, en facilitant la mise au point de ... more
This protocol is to help researchers working with freshwater gastropods related to the transmission of schistosomes, and particularly those looking at extracting high quality intact DNA for next generation sequencing purposes. This protocol offers a general outline that can be tailored to the conten... more
En el último decenio, los datos de las secuencias genéticas de los patógenos han adquirido un papel crucial en la detección y el manejo de los brotes de enfermedades infecciosas, contribuyendo al desarrollo de pruebas diagnósticas, medicamentos y vacunas y orientando la respuesta sanitaria.
Sequencing SARS-CoV-2 in the Americas The COVID-19 Genomic Surveillance Regional Network was created in 2020 not only to strengthen the sequencing capacity in the participating laboratories, but also for them to establish a routine SARS-CoV-2 genomic sequencing, as a strategy to increase the amoun... more
Africa CDC Institute of Pathogen Genomics (IPG) was launched in November 2019 and operates under the Division of Laboratory Systems and Networks. IPG coordinate the implementation of molecular diagnostics, pathogen genomics and bioinformatics in National Public Health Institutions (NPHIs) and/or Re... more
Representative, quality, timely and continuous genetic surveillance of SARS-CoV-2 is critical to the COVID-19 outbreak response. This document provides practical guidance to Global Influenza Surveillance and Response System (GISRS) laboratories and other relevant national laboratories to move beyond... more
WHO-2019-nCoV-genomic_sequencing
his guidance provides interim guidance for the integration of SARS-CoV-2 and influenza virologic and genomic surveillance, from sentinel site case enrolment and sampling to the eventual sharing of the virus sequence data, a process known as end-to-end surveillance. This guidance builds on experience... more

COVID-19 virus mutation tracker

KAUST Rapid Research Response Taskforce (R3T) and CBRC King Abdullah University of Science and Technology (2021) CC
A COVID-19 virus mutation tracker system (CovMT; appendix) based on SARS-CoV-2 isolate genomes deposited to GISAID to track the worldwide sequencing efforts and the evolution of the mutational landscape of this virus. CovMT, which is updated daily, summarises mutations from more than 450 000 isola... more
Data available for your search include drug targets, tested compounds, existing drugs, ethnopharmacological plants, and information on the genome of M. ulcerans
Die weltweite Ungleichheit bei der Verteilung von Einkommen und Vermögen weit jenseits dessen, was sich durch Unterschiede der Belastung oder Verantwortung durch die jeweilige Arbeitstätigkeit begründen ließe, stellt schon für sich genommen eine gewaltige Ungerechtigkeit dar. Sie steht auch in ... more