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The global burden of disease due to mental disorders continues to rise, especially in low- and middle-income countries (LMIC). In addition to causing a large proportion of morbidity, mental disorders – especially severe mental disorders (SMD) – are linked with poorer health outcomes and increase... more
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Q7. SCOPING QUESTION: In adults with moderate-severe depressive disorder, what is the effectiveness and safety of antidepressant medication (ADM) in comparison with psychological treatment? The WHO mhGAP programme’s existing guidelines recommend that either structured brief psychological treatm... more
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Birth defect has been an emerging major cause of child mortality in the region. Scarcity of the birth defects information hampers policy decisions and control measures at national level. In order to create evidence for action for birth defects prevention in the region, WHO-SEARO in collaboration wit... more
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Cost–effectiveness of community-based practitioner programmes in Ethiopia, Indonesia and Kenya

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Over the past two decades, Afghanistan has depended on international donor support to fund essential services like health care. But this donor support has been falling for years and will likely to continue do so—perhaps precipitously—following the announcement by United States President Joe Bide... more
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Clinical features of Chagas disease progression and severity

Nunes, M.C.P.; C. Bern, E.H. Clark, et al. (2024) CC
The Lancet Regional Health Americas Volume 37100832 September 2024
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Investing in and building longer-term health emergency preparedness during the COVID-19 pandemic
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World Health Organization WHO (2020) C_WHO
Interim Guidance This document is to help Member States build on actions taken during the COVID-19 pandemic to improve national medium- to long-term preparedness for future threats. It maps COVID-19 preparedness and response actions to the building of sustainable International Health Regulations (2... more
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Zika Strategic Response Plan: Revised For July 2016 – December 2017
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World Health Organization WHO; PAHO (2016) C_WHO
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Psychological & Mental Health First Aid for All

World Federation for Mental Health (WFMH) (2016) C1
Dignity in Mental Health
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WHO recommendation on advance misoprostol distribution to pregnant women for prevention of postpartum haemorrhage

World Health Organization (2020) C_WHO
The recommendation in this document thus supersedes the previous WHO recommendation for the prevention of PPH as published in the 2012 guideline, WHO recommendations for the prevention and treatment of postpartum haemorrhage.
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Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study

GBD 2019 Blindness and Vision Impairment Collaborator The Lancet (2020) CC
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Findings and Recommendations from the Noncommunicable Diseases and Injuries (NCDI) Commission of Ethiopia

Federal Democratic Republic of Ethiopia -Ministry of Health (2018) C1
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Guidelines for Pharmacovigilance and Medicine Information System in Rwanda

Ministry of Health, Rwanda (2011) C2
The purpose of these guidelines is to help health workers to participate in the process of continuous surveillance of safety and efficacy of the pharmaceutical products which are used in clinical practice, thus help to achieve the ultimate goal to make safer and more effective treatment available to... more
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Updates on the management of severe acute malnutrition in infants and children
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World Health Organization (2013) C_WHO
This guideline provides global, evidence-informed recommendations on a number of specific issues related to the management of severe acute malnutrition in infants and children, including in the context of HIV.
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Guidelines for the Diagnosis, Treatment and Prevention of Leprosy
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World Health Organization WHO (2018) C_WHO
The Guidelines for the Diagnosis, Treatment and Prevention of Leprosy provide state-of-the-art knowledge and evidence on leprosy diagnosis, treatment and prevention based on a public health approach in endemic countries. The target audience of this document includes policy-makers in leprosy or infec... more
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COVID-19 and the social determinants of health and health equity: evidence brief

World Health Organization WHO (2021) C_WHO
6 December 2021
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Guidance on Law and Public Health Emergency Preparedness and Response

International Federation of Red Cross and Red Crescent Societies IFRC (2023) CC
The domestic regulation of public health emergencies (PHEs) is inextricably linked to the regulation of other types of disaster. PHEs are usually governed at least partly by general disaster and emergency laws. Moreover, there is significant overlap in the legal mechanisms used to respond to PHEs an... more