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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Informal consultation on end-game challenges for trachoma elimination

World Health Organization WHO (2022) C_WHO

Since 1996, trachoma has been targeted for elimination as a public health problem worldwide. The active trachoma criterion for national elimination as a public health problem is a TF1–9 < 5%, sustained for at least two years in the absence of antibiotic mass drug administration (MDA), in each form... more

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The Power of Cities: Tackling Noncommunicable Diseases and Road Traffic Injuries

World Health Organization WHO (2019) C_WHO

The report is geared towards mayors, local government officials and city policy planners.It highlights key areas where city leaders can tackle the drivers of NCDs, including tobacco use, air pollution, poor diets and lack of exercise, and improve road safety. From anti-tobacco actions in Beijing a... more

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Influencing food environments for healthy diets

Food and Agriculture Organization of the United Nations FAO (2016) C2

Food environments are usually defined as the settings with all the different types of food made available and accessible to people as they go about their daily lives. That is, the range of food in supermarkets, small retail outlets, wet markets, street food stalls, coffee shops, tea houses, s...chool canteens, restaurants, and all the other venues where people buy and eat food. These environments differ enormously depending on the context. They can be extensive and diverse, with a seemingly endless array of options and price ranges, or they can be sparse, with very few options on offer. Because they determine what food consumers can access at a given moment in time, at what price, and with what degree of convenience, food environments both constrain and prompt the consumer’s choice.Food environments are influenced by the food systems which supply them, and vice versa. Food systems encompass the entire range of activities, people and institutions involved in the production, processing, marketing, consumption and disposal of food (FAO, 2013). They include but are not limited to food supply chains. Making food systems nutrition-sensitive can contribute to addressing all forms of malnutrition, as food systems determine whether the food needed for good nutrition are available, affordable, acceptable and of adequate quantity and quality. How closely food systems and food environments are interrelated and interdependent, and the degree to which external factors affect nutrition outcomes, varies from setting to setting.Many of today’s food systems and food environments are challenged in supporting consumer choices that are consistent with healthy diets and good nutrition. Consumers are not making choices based on nutrition and health, and poor diet is now the number one risk factor for death and disability worldwide (GBD, 2015). Food systems that do not enable healthy diets are increasingly recognized as an underlying cause of malnutrition (GLOPAN, 2016), and malnutrition, irrespective of form, has a huge cost. Economic costs associated with undernutrition are estimated at $1-2 trillion per year, about 2-3% of global GDP (FAO, 2013); the global economic cost of obesity and associated diet-related non-communicable diseases is estimated at $2 trillion per year, about 2.8% of global GDP (McKinsey, 2014). Influencing food environments for promoting healthy diets is an emerging strategy to address today’s nutrition challenges. more

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Mental Health in Haiti: Beyond Disaster Relief

Olivia Tiberi The Journal of Global Health (2016) C1

Haiti, one of the poorest countries in the world, was devastated by an earthquake in 2010. The disaster uncovered the realities of a non-existent mental health care system with only ten psychiatrists nationwide. Attempts were made to assess the increased prevalence of mental illness, likely due to t... more

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Реагирование на COVID-19: факторы, которые необходимо учесть в отношении детей и взрослых с инвалидностью

unicef UNICEF (2020) C_UNICEF

Что нам необходимо знать? Что нам необходимо делать? Рекомендации в отношении детей и взрослых с инвалидностью во времена Ковида Responding to COVID-19: factors to consider for children a... more

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Women’s Access to Health Care in Afghanistan

Human Rights Watch (2021) CC

Over the past two decades, Afghanistan has depended on international donor support to fund essential services like health care. But this donor support has been falling for years and will likely to continue do so—perhaps precipitously—following the announcement by United States President Joe Bide... more

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Children's Palliative Care in South Africa

international children's palliative care network (icpcn) t (2020) C1

Accessed 1 October 2020

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Children’s Vantage Point of Recalling Traumatic Events (RESEARCH ARTICLE)

Katie S. Dawson, Richard A. Bryant PLOS ONE (2015) CC

This study investigated the recollections of child survivors of the 2004 Asian tsunami in terms of their vantage point and posttraumatic stress disorder (PTSD) responses. Five years after the tsunami, 110 children (aged 7–13 years) living in Aceh, Indonesia were assessed for source of memories of ... more

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NIGERIA’S CALL TO ACTION TO SAVE NEWBORN LIVES

Federal Ministry of Health, Nigeria (2014) C2

Nigeria is committed to end preventable newborn deaths, making life-saving interventions available to all mothers and babies who need them.

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Медикосоциальные аспекты реабилитации больных с пограничными психическими расстройствами

Карелина Д. Д., Кром И. Л., Барыльник Ю. Б. Саратовский научно-медицинский журнал. (2011) C1

Рассматриваются факторы, оказывающие влияние на процесс медикосоциальной реабилитации больных с пограничными психическими расстройствами в современном социуме... more

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Trainer’s Guide for Conducting Training of Auxiliary Nurse Midwives Lady Health Visitors Staff Nurses

Ministry of Health & Family Welfare Government of India (2010) C1

Skilled Birth Attendance

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The State of the World’s Children 2023

UN Children's Fund UNICEF (2024) CC

The article focuses on "The State of the World’s Children 2023" report published by UNICEF. It highlights the critical role of vaccines in saving lives and the challenges in global immunization efforts, especially for marginalized and underserved children. The report emphasizes the impact of COVID... more

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Young People’s Guide to Climate Change and Children’s Health

UN Children's Fund UNICEF (2024) CC

“We must not forget that no matter where we are or how old we are, we can all work for life and take action.” Francisco Vera, 15, UNICEF Child Advocate The Young Climate Activists toolkit was created by advocates of all ages who, like you, are deeply concerned about our planet's future. Havin... more

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Monitoring children’s development in Europe and central Asia with a focus on primary health care: directions for policy and practice

World Health Organisation (WHO) (2024) C_WHO

This publication aims to provide an overview of the state of developmental monitoring in selected countries across the Europe and Central Asia region (ECAR), to document the existing evidencebased approaches and models for developmental monitoring and to identify the key considerations necessary to ... more

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The climate crisis is a child rights crisis: Introducing the children’s climate risk index

UN Children's Fund UNICEF (2021) C_UNICEF

Young people living in the Central African Republic, Chad, Nigeria, Guinea, and Guinea-Bissau are the most at risk of the impacts of climate change, threatening their health, education, and protection, and exposing them to deadly diseases. The report is the first comprehensive analysis of climate ri... more

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Implementing Afghanistan’s Elimination of Violence against Women Law

Human Rights Watch (2021) CC

The international reconstruction effort in Afghanistan after 2001 created an opportunity to advance human rights, and women’s and girls’ rights in particular. Although its achievements have fallen short of what was envisioned, significant improvements in legal protections have emerged through th... more

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Социальная защита с учетом гендера в период COVID 19: Техническая записка

unicef UNICEF (2020) C_UNICEF

Данная техническая записка направлена на предоставление простого чек-листа для лиц, вырабатывающих политику, партнеров и персонала ЮНИСЕФ, в их работе над проек�... more

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Как поговорить с ребенком о коронавирусе?

UNESCO Institute for Information Technologies in Education , Joint United Nations Programme on HIVAIDS UNESCO (2020) CC

Инфографики для населения How to talk to your child about the coronavirus?