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In conclusion, the current evidence does not support the use of mpox antigen RDTs in the field. More data are expected from independent evaluations conducted by Africa CDC, FIND or other organizations
Diagnostic de mpox.
Biosafety involves the implementation of containment principles, technologies and practices to prevent unintentional exposure to biological agents. Biosecurity involves the protection, control and accountability of biological materials and information related to these materials and dualuse research,
...
to prevent their unauthorized access, loss, theft, misuse, diversion or intentional release.
more
Measles outbreak guide
recommended
This guide also draws on the standard operating procedures (SOPs) to apply for measles outbreak response
support from the Measles & Rubella Initiative Outbreak Response Fund (17) and includes a sec
...
tion on
measles outbreak recovery so that contributing factors and potential root causes are identified and
addressed systematically after a measles outbreak. This guide does not aim to be a comprehensive guide
on measles elimination or routine immunization (RI) more broadly.
more
El documento es una guía de bolsillo para establecer y operar un Centro de Tratamiento de Cólera (CTC). Proporciona pautas para seleccionar la ubicación, clasificar a los pacientes según la gravedad de la deshidratación, implementar medidas de control de infecciones y garantizar el suministro a
...
decuado de materiales médicos. La guía enfatiza la importancia de mantener la higiene, gestionar adecuadamente los desechos y garantizar la seguridad, al tiempo que ofrece protocolos detallados para tratar casos moderados y graves de cólera. Está diseñada para apoyar a los trabajadores de la salud en la gestión eficiente de los brotes de cólera.
more
Factsheet for everyone
Integrated Outbreak Analytics (IOA) applies a multidisciplinary approach to understanding outbreak dynamics and to inform outbreak response. It aim
...
s to drive comprehensive, accountable, and effective public health and clinical strategies by enabling communities, and national and subnational health authorities to use data for operational decision-making. IOA embraces a holistic perspective of outbreak dynamics throughout: from the trigger questions to the data that are collected or accessed, to the interpretation of results and the recommendations that follow. In addition, IOA promotes co-development and monitoring of evidence informed actions.
The IOA toolkit aims to provide a clear understanding of IOA and highlight the importance of using an integrated, holistic approach to manage outbreak responses. It provides step-by-step guidance for setting up IOA and putting IOA principles into action. Finally, this toolkit provides guidance on applying IOA in humanitarian and emergency contexts, offering a practical and adaptable approach to informing public health emergency responses.
Developed based on the model from the Democratic Republic of the Congo (DRC), its creation involved extensive consultation with experts experienced in IOA applications. The toolkit was piloted in Tanganyika Province, DRC, as well as Somalia and Sudan, demonstrating its adaptability to diverse emergency scenarios. It builds upon an existing array of tools, templates, reports, case studies, animations, and publications used by stakeholders in diverse contexts.
more
The document is a practical handbook developed by the European Centre for Disease Prevention and Control (ECDC) that provides guidance on how to design, plan, conduct, and evaluate simulation exercises in public health settings. Its main purpose is
...
to help organisations improve their preparedness and response to communicable disease outbreaks by using structured exercises as a training and evaluation tool. The handbook explains different types of exercises, outlines the steps involved in organising them, and highlights the importance of clear objectives, coordination, and evaluation. Overall, it aims to strengthen emergency preparedness by enabling organisations to identify weaknesses, improve collaboration, and enhance their ability to respond effectively to public health crises.
more
The document is a pocket guide for establishing and operating a Cholera Treatment Center (CTC). It provides guidelines on selecting a location, triaging patients based on dehydration severity, infection control measures, and ensuring sufficient medical supplies. The guide emphasizes maintaining hygi
...
ene, proper waste management, and security while offering detailed protocols for treating moderate and severe cases of cholera. It is intended to support healthcare workers in efficiently managing cholera outbreaks.
more
Le document est un guide de poche pour établir et gérer un Centre de Traitement du Choléra (CTC). Il fournit des directives pour choisir l’emplacement, classer les patients selon la gravité de leur déshydratation, mettre en œuvre des mesures de contrôle des infections et garantir un approvi
...
sionnement adéquat en matériel médical. Le guide met l’accent sur l’importance de maintenir l’hygiène, de gérer correctement les déchets et d’assurer la sécurité, tout en offrant des protocoles détaillés pour traiter les cas modérés et graves de choléra. Il est conçu pour soutenir les professionnels de santé dans la gestion efficace des épidémies de choléra.
more
The CDC's "About Cholera" webpage provides essential information on cholera, an intestinal infection caused by the bacterium Vibrio cholerae. It highlights that cholera is primarily spread through contaminated water and food, leading to severe diarrhea, dehydration, and potentially death if untreate
...
d. Individuals in areas with unsafe drinking water, poor sanitation, and inadequate hygiene are at the highest risk. The page emphasizes the importance of early and proper treatment, such as rehydration therapy, to improve survival rates. Preventative measures include using treated water, practicing good hygiene, and vaccination, especially for travelers to regions where cholera is prevalent.
more
The monkeypox virus (MPXV) clade I epidemic that has been affecting the Democratic Republic of the Congo
(DRC) since November 2023 has recently spread to several other African countries including Burundi, Rwanda,
Uganda and Kenya. The size of these outbreaks could be larger than reported due to un
...
der-ascertainment and
under-reporting.
more
Patient's Guide
Resource Platform
This document outlines the plan for a continental cholera prevention and control with the implementation framework for the Cholera IMST, detailing its governance structure, strategic priorities, and operational modalities
Conducting a Field Investigation
King Mich.; Bensyl D.; Goodman R.; Rasmussen S.
Center for Disease Control and Prevention CDC
(2025)
C_CDC
This chapter describes the step-by-step process required in performing an epidemiologic field investigation. The 10 steps covered here build on and further refine the steps that have been taught traditionally in the Centers for Disease Control and Preventi
...
on's (CDC) annual Epidemic Intelligence Service courses, in the three previous editions of this manual (the textbook Field Epidemiology), and in other CDC instructional programs.
more
The text “Pathogen Genomic Surveillance Policy Framework (2023)” is a strategic framework developed by Africa CDC to strengthen genomic surveillance of pathogens in the Member States of the African Union.
Its content focuses on how African countries can systematically integrate genome sequencin
...
g into their public health systems in order to detect infectious diseases more rapidly, monitor outbreaks more effectively, and support evidence-based public health decision-making.
The report was developed in the context of the COVID-19 pandemic, which demonstrated the importance of genomic surveillance for identifying virus variants and enabling effective crisis management. The aim of the framework is to sustainably expand the capacities built during the pandemic and to apply them to additional pathogens beyond COVID-19.
more
