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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Transforming Agriculture in Southern Africa

Sikora, R.A.; et al. Routledge (2020) CC

Constraints, Technologies, Policies and Processes

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Health workforce policy and management in the context of the COVID-19 pandemic response

World Health Organization WHO (2021) C_WHO

This guide is available in English, French, Spanish, Russian, Arabic and Chinese This guide consolidates COVID-19 guidance for human resources for health managers and policy-makers at national, subnational and facility levels to design, manage and preserve the workforce necessary to manage the COVI... more

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Neonatal vitamin A supplementation

World Health Organization WHO (2011)

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Namibia: National Public Health Laboratory Policy

Ministry of Health and Social Services (MOHSS) (2012) C1

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Kenya Palliative Care Policy 2021-2030

Republic of Kenya, Ministry of Health (2021) CC

Globally, approximately 56.8 million people are in need of palliative care services; 78% of them living in low and middle-income country yet only about 12% have their needs being met causing great suffering for many.

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COVID-19 strategic preparedness and response plan: operational planning guideline: 1 February 2021 to 31 January 2022

World Health Organization WHO (2021) C_WHO

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Vitamin A supplementation in infants and children 6–59 months of age

World Health Organization World Health Organization (2011)

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United to end TB - Every word counts

Stop TB Partnership; UNOPS; END TB (2017) C1

Suggested language and usage for tuberculosis communications First edition Accessed November 2017

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Online Temptations: COVID-19 and Religious Misinformation in the MENA Region

Alimardani, M. and Mona Elswah (2020) CC

Social Media + SocietyJuly-September 2020: 1 –4

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Health workforce development and retention in Guinea: a policy analysis post-Ebola

van de Pas R., Kolie D., Delamou A., Van Damme W. BMC - Biomed Central (2019) CC

The state of the Guinean health workforce is one of the country’s bottlenecks in advancing health outcomes. The impact of the 2014–2015 Ebola virus disease outbreak and resulting international attention has provided a policy window to invest in the workforce and reform the health system. This re... more

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Operational handbook on tuberculosis: module 6: tuberculosis and comorbidities, 3rd ed

World Health Organization WHO (2025) C_WHO

Addressing comorbidities and risk factors for tuberculosis (TB) is a crucial component of the World Health Organization (WHO)’s End TB Strategy. This WHO operational handbook on tuberculosis. Module 6: tuberculosis and comorbidities aims to support countries in scaling up people-centred care, ... more

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Предотвращение самоубийств - Глобальный императив

Shekhar Saxena , Etienne Krug, Oleg Chestnov et al. World Health Organization (WHO) (2014) C_WHO

Цель данного доклада – стать ресурсом, позволяющим руководителям и другим заинтересованным сторонам рассматри-вать предупреждение самоубийств как императив. То�... more

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Plan estratégico de preparación y respuesta frente a la COVID-19. Orientación para la planificación operativa

World Health Organization WHO (2021) C_WHO

En el Plan estratégico de preparación y respuesta frente a la COVID-19, del 2021, la Organización Panamericana de la Salud invita a las autoridades nacionales a actualizar los planes nacionales para la COVID-19 a fin de incorporar las enseñanzas extraídas a lo largo del 2020, de prever los reto... more

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Contingency Fund for Emergencies 2022 annual report Enabling quick action to save lives

World Health Organisation (WHO) (2023) C_WHO

The Contingency Fund for Emergencies (CFE) provides WHO with rapid and flexible resources to respond to disease outbreaks and other health emergencies. The annual report provides an overview of the use and impact of the Fund over the previous year.

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Strategic Communication for Zika Prevention: A Framework for Local Adaptation

Alice Payne Merritt, Gabrielle Hunter, Anne Ballard et al. ohns Hopkins Center for Communication Programs (2017) C1

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A Comprehensive HIV Prevention Roadmap 2017-2021

Ministry of Health, Zambia (2017) C1

Framework of Indictors and Targets

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Kenya National Cancer Sreening Guidelines

Ministry of Health, Kenya (2018) CC

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Situational Analysis on Post-Rape Care of Children in Lesotho

Levy, Marcy, Veronica Magar, and Derrick Sialondwe Arlington, VA: USAID’s AIDS Support and Technical Assistance Resources, AIDSTAR-One, Task Order 1 (2013)

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WHO competency framework, risk communication and community engagement

World Health Organization WHO (2024) C_WHO

The risk communication and community engagement (RCCE) competency framework is a resource that details the essential behaviours and activities necessary for effective communication and engagement with communities before, during and after public health emergencies. The purpose of this framework is to... more